A single ion imaging-based detection method and device areprovided. After being reflected by an electromodulationsingularity coupling differential imaging reaction unit,aprobe beam from a total internal reflection ellipsometryimager converges on a CCD or CMOS detector, the acquiredsensing surface image data is transmitted to a signal pro-cessing unit, the common mode noise is eliminated byperforming spectral analysis on differential signals of aworking sensing surface and a reference sensing surface, thepeak intensity of a modulating signal is selected on thespectrum for wave filtering to obtain a real-time signal ofinteraction of single ions or charged molecules at a solid-liquid interface. Based on the singularity effect at a surfaceplasma resonance angle of an ellipsometry phase and acorresponding optical signal noise suppression scheme, thepresent application can achieve real-time observation of theadsorption of single ions or charged molecules at a solidsurface.
修改评论