| Osmotic Pressure and Its Biological Implications | |
Zheng SJ(郑松杰)1,2; Li, Yan1; Shao YF(邵颖峰)1; Li, Long1,2 ; Song F(宋凡)1,2
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| Corresponding Author | Li, Long(lilong@lnm.imech.ac.cn) ; Song, Fan(songf@lnm.imech.ac.cn) |
| Source Publication | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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| 2024-03-01 | |
| Volume | 25Issue:6Pages:18 |
| ISSN | 1661-6596 |
| Abstract | Gaining insight into osmotic pressure and its biological implications is pivotal for revealing mechanisms underlying numerous fundamental biological processes across scales and will contribute to the biomedical and pharmaceutical fields. This review aims to provide an overview of the current understanding, focusing on two central issues: (i) how to determine theoretically osmotic pressure and (ii) how osmotic pressure affects important biological activities. More specifically, we discuss the representative theoretical equations and models for different solutions, emphasizing their applicability and limitations, and summarize the effect of osmotic pressure on lipid phase separation, cell division, and differentiation, focusing on the mechanisms underlying the osmotic pressure dependence of these biological processes. We highlight that new theory of osmotic pressure applicable for all experimentally feasible temperatures and solute concentrations needs to be developed, and further studies regarding the role of osmotic pressure in other biological processes should also be carried out to improve our comprehensive and in-depth understanding. Moreover, we point out the importance and challenges of developing techniques for the in vivo measurement of osmotic pressure. |
| Keyword | osmotic pressure cell division cell differentiation lipid phase separation |
| DOI | 10.3390/ijms25063310 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:001192787100001 |
| WOS Keyword | FREE-SOLVENT MODEL ; RECEPTOR-LIGAND BINDING ; MECHANICAL-PROPERTIES ; LIPID RAFTS ; CELL-SHAPE ; BINARY ; VOLUME ; STRESS ; COEFFICIENTS ; MEMBRANES |
| WOS Research Area | Biochemistry & Molecular Biology ; Chemistry |
| WOS Subject | Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary |
| Funding Project | National Natural Science Foundation of China |
| Funding Organization | National Natural Science Foundation of China |
| Classification | 二类/Q1 |
| Ranking | 1 |
| Contributor | Li, Long ; Song, Fan |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://dspace.imech.ac.cn/handle/311007/94879 |
| Collection | 非线性力学国家重点实验室 |
| Affiliation | 1.Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing Key Lab Engn Construct & Mechanobiol, Beijing 100190, Peoples R China; 2.Univ Chinese Acad Sci, Ctr Mat Sci & Optoelect Engn, Sch Engn Sci, Beijing 100049, Peoples R China |
| Recommended Citation GB/T 7714 | Zheng SJ,Li, Yan,Shao YF,et al. Osmotic Pressure and Its Biological Implications[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2024,25,6,:18. |
| APA | 郑松杰,Li, Yan,邵颖峰,Li, Long,&宋凡.(2024).Osmotic Pressure and Its Biological Implications.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,25(6),18. |
| MLA | 郑松杰,et al."Osmotic Pressure and Its Biological Implications".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 25.6(2024):18. |
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