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| Spring constant regulate selectin-ligand bond dissociation 会议论文 第五届中美生物医学工程暨海内外生物力学学术研讨会, 中国北京/Beijing, China, 2013-08-01 Authors: Zhang Y(章燕); Sun GY(孙淦云); Lv SQ(吕守芹); Long M(龙勉) View  |  Adobe PDF(91Kb)  |  Favorite  |  View/Download:504/122  |  Submit date:2014/04/02 Dissociation Regulate Selectin Constant Formation Further Increased Stiffness Lifetime Ligand Binding Assay Probe Force Kinetics Mainly Reverse Values Well Found |
| Impact of probe stiffness on receptor-ligand bond dissociation 会议论文 the 3rd Asia Pacific Protein Association Conference in Conjunction with the 3rd Symposium of the Chinese Protein Society, 中国北京/Beijing, China, 2011-05-06 Authors: Zhang Y(章燕); Sun GY(孙淦云); Lv SQ(吕守芹); Long M(龙勉) View  |  Adobe PDF(77Kb)  |  Favorite  |  View/Download:376/92  |  Submit date:2014/04/02 Stiffness Receptor Dissociation Ligand Probe Molecule Probe Formation Force Cario Barrier Determine Metastasis Mainly Governed Irreversible Bonds Theorem Effect Energy |
| 加载历史对低刚度下P-选择素-PSGL-1键寿命的影响 期刊论文 医用生物力学, 2009, 卷号: 24, 期号: 增刊1, 页码: 26-27 Authors: 章燕; 孙淦云; 吕守芹; 李宁; 龙勉 Adobe PDF(126Kb)  |  Favorite  |  View/Download:769/150  |  Submit date:2010/05/03 加载历史:5107 选择素:5028 低刚度:4013 寿命:3064 加载率:2582 配体分子:2236 蛋白质间相互作用:2231 受体:1907 调控因素:1243 炎症反应:1139 |
| 加载历史对低刚度下P-选择素-PSGL-1键寿命的影响 会议论文 第九届全国生物力学学术会议, 中国天津, 2009-10-11 Authors: 章燕; 孙淦云; 吕守芹; 李宁; 龙勉 Adobe PDF(177Kb)  |  Favorite  |  View/Download:609/116  |  Submit date:2010/11/25 加载历史 5481 低刚度 5238 选择素 4629 加载率 2744 寿命 2051 配体分子 1986 相互作用 1489 加载速度 1080 977 外力 1029 炎症反应 |
| Parametric Analysis for Monitoring 2D Kinetics of Receptor-Ligand binding 期刊论文 Cellular and Molecular Bioengineering, 2009, 卷号: 2, 期号: 4, 页码: 495-503 Authors: Sun GY(孙淦云); Zhang Y(章燕); Huo B(霍波); Long M(龙勉) Adobe PDF(1749Kb)  |  Favorite  |  View/Download:895/241  |  Submit date:2009/12/30 |
| Surface-Bound Selectin-Ligand Binding Is Regulated By Carrier Diffusion 期刊论文 European Biophysics Journal With Biophysics Letters, 2009, 页码: 701-711 Authors: Sun GY(孙淦云); Zhang Y(章燕); Huo B(霍波); Long M(龙勉); Long M Adobe PDF(559Kb)  |  Favorite  |  View/Download:800/192  |  Submit date:2009/08/03 Association Kinetics Regulating Factors Carrier Diffusion Optical Trap Selectin Ligand Mediated Cell-adhesion P-selectin Glycoprotein Ligand-1 Optical Tweezers Shear-flow Human Neutrophils Force Microscopy Association Rate Contact Area Kinetics |
| Force spectroscopy of single receptor-ligand bond using an optical trap 会议论文 2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009, Shanghai, China, November 2, 2009 - November 6, 2009 Authors: Zhang Y(章燕); Sun GY(孙淦云); Li N(李宁); Huo B(霍波); Lv SQ(吕守芹); Long M(龙勉); Zhang, Y. Adobe PDF(2190Kb)  |  Favorite  |  View/Download:130/50  |  Submit date:2017/07/14 Bond Dissociation Force Spectroscopy Low Loading Novel Methods Optical Trap Receptor-ligand Bonds Receptor-ligand Interactions Thermal Fluctuations Unbinding Transitions |
| 采用热涨落方法直接测量受体-配体二维正反应率 学位论文 博士论文,北京: 中国科学院研究生院, 2008 Authors: 孙淦云 Adobe PDF(4504Kb)  |  Favorite  |  View/Download:533/0  |  Submit date:2009/04/13 |
| Quantifying rupture force and bond lifetime of P-selectin-PSGL-1 interactions at lower forces 会议论文 Advances in Heterogeneous Material Mechanics 2008 - 2nd International Conference on Heterogeneous Material Mechanics, ICHMM 2008, Huangshan, China, June 3, 2008 - June 8, 2008 Authors: Zhang Y(章燕); Sun GY(孙淦云); Huo B(霍波); Long M(龙勉) Favorite  |  View/Download:124/0  |  Submit date:2017/06/01 Applied Forces Atomic Forces Biological Processes Bond Dissociations Bond Lifetimes Bond Ruptures External Forces Flow Chambers Glycoprotein Ligands Life-times Ligand Interactions Loading Rates Optical Traps Physiological Flows Rupture Forces Selectin Spring Constants Thrombosis Formations To Many Tumor Metastases |
| Low Spring Constant Regulates P-Selectin-Psgl-1 Bond Rupture 期刊论文 Biophysical Journal, 2008, 页码: 5439-5448 Authors: Zhang Y(章燕); Sun GY(孙淦云); Lv SQ(吕守芹); Li N(李宁); Long M(龙勉); Long, MA (reprint author), Chinese Acad Sci, Natl Micrograv Lab, Beijing 100190, Peoples R China. Adobe PDF(634Kb)  |  Favorite  |  View/Download:975/212  |  Submit date:2009/08/03 Selectin Glycoprotein Ligand-1 P-selectin Cell-adhesion Binding-kinetics Force Dissociation Lifetime Flow Microscope Leukocytes |