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Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
作者:  Shu XY(舒芯钰);  Li N(李宁);  Wu Y(武亿);  Li W(李旺);  Zhang XY(张晓宇);  Li PW(李培文);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1359Kb)  |  收藏  |  浏览/下载:430/119  |  提交时间:2021/05/06
Liver sinusoidal endothelial cell  Shear stress  Mechanical stretch  Extracellular matrix  Stiffness  
Flow field analyses of a porous membrane-separated, double-layered microfluidic chip for cell co-culture 期刊论文
ACTA MECHANICA SINICA, 2020, 页码: 14
作者:  Chen SB(陈深宝);  Xue J(薛健);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Zhou LW(周吕文);  Feng SL(冯世亮);  Cui YH;  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(5919Kb)  |  收藏  |  浏览/下载:311/147  |  提交时间:2020/08/26
Immersed boundary method  Porous membrane  Wall shear stress  Penetration velocity  Microfluidic chip  
Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
作者:  Shu XY(舒芯钰);  Li N(李宁);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
浏览  |  Adobe PDF(1108Kb)  |  收藏  |  浏览/下载:511/192  |  提交时间:2020/04/07
beta(2) integrin  Ligands  Calcium transients  Bond strength  Mechanotransduction  Shear stress  
Life Science in Space: Experiments on Board the SJ-10 Recoverable Satellite 专著
Beijing;Singapore:Science Press; Springer, 2019
作者:  Editors: Duan EK;  Long M(龙勉)
Adobe PDF(21614Kb)  |  收藏  |  浏览/下载:294/0  |  提交时间:2019/12/18
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
作者:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
浏览  |  Adobe PDF(865Kb)  |  收藏  |  浏览/下载:435/203  |  提交时间:2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Mechanomics: an emerging field between biology and biomechanics 期刊论文
Protein & Cell, 2014, 卷号: 5, 期号: 7, 页码: 518-531
作者:  Wang JW;  Lv DY(吕东媛);  Mao DB(毛德斌);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Ctr Biomech & Bioengn, Beijing 100190, Peoples R China.
浏览  |  Adobe PDF(587Kb)  |  收藏  |  浏览/下载:722/247  |  提交时间:2014/09/03
Mechanomics  Mechanobiology  Proteomics  Transcriptomics  
Visualization of Allostery in P-Selectin Lectin Domain Using Md Simulations 期刊论文
PLOS ONE, 2010, 卷号: 5, 期号: 12, 页码: -
作者:  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉);  Lu, SQ (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100080, Peoples R China.
Adobe PDF(1140Kb)  |  收藏  |  浏览/下载:258/84  |  提交时间:2016/02/01
Molecular Modeling and Affinity Determination of scFv Antibody: Proper Linker Peptide Enhances Its Activity 期刊论文
Annals of Biomedical Engineering, 2010, 卷号: 38, 期号: 2, 页码: 537-549
作者:  Gu X;  Jia XL(贾潇凌);  Feng JN;  Shen BF;  Huang Y;  Geng SS;  Sun YX;  Wang Y;  Li Y;  Long M(龙勉);  Long M(龙勉)
浏览  |  Adobe PDF(616Kb)  |  收藏  |  浏览/下载:1959/641  |  提交时间:2009/12/31
Linker Peptide  Molecular Modeling  Micropipette Adhesion Frequency  Scatchard Analysis  Binding Affinity