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力致β2整合素变构的微观结构基础 会议论文
第十二届全国生物力学学术会议暨第十四届全国生物流变学学术会议会议, 中国陕西西安, 2018年8月17日至21日
Authors:  吕守芹;  毛德斌;  张潇;  龙勉
View  |  Adobe PDF(161Kb)  |  Favorite  |  View/Download:187/47  |  Submit date:2019/11/21
动力学  整合素  结构-功能关系  微观结构  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
Authors:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
View  |  Adobe PDF(865Kb)  |  Favorite  |  View/Download:412/195  |  Submit date:2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Salt bridge interactions within the beta(2) integrin alpha(7) helix mediate force-induced binding and shear resistance ability 期刊论文
FEBS JOURNAL, 2018, 卷号: 285, 期号: 2, 页码: 261-274
Authors:  Zhang X(张潇);  Li LD;  Li N(李宁);  Shu XY;  Zhou LW(周吕文);  Lv SQ(吕守芹);  Chen SB;  Mao DB;  Long M(龙勉)
View  |  Adobe PDF(2053Kb)  |  Favorite  |  View/Download:256/70  |  Submit date:2018/10/30
beta(2) integrin  allostery  conformational stability  force  salt bridge interaction