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Real-time structural signatures of protein allostery by electrically- and mechanically-coupled sensing 期刊论文
NANO TODAY, 2024, 卷号: 55, 页码: 10
作者:  Zhang, Mingkun;  Zheng, Zhi;  Zhou, Jin;  Ding, Qihan;  Long, Mian;  Lue, Shouqin
收藏  |  浏览/下载:17/0  |  提交时间:2024/03/25
Nanopore sensing  Atomic force microscopy (AFM)  Protein allostery  Steered molecular dynamics (SMD)  Spheroid approximation  
A computational method for the load spectra of large-scale structures with a data-driven learning algorithm 期刊论文
SCIENCE CHINA-TECHNOLOGICAL SCIENCES, 2023, 卷号: 66, 期号: 1, 页码: 141-154
作者:  Chen XJ(陈贤佳);  Yuan, Zheng;  Li, Qiang;  Sun, ShouGuang;  Wei YJ(魏宇杰)
Adobe PDF(2512Kb)  |  收藏  |  浏览/下载:273/84  |  提交时间:2023/02/09
load spectrum  computational mechanics  deep learning  data-driven modeling  gated recurrent unit neural network  
Distinct binding kinetics of E-, P- and L-selectins to CD44 期刊论文
FEBS JOURNAL, 2022, 页码: 18
作者:  Li LD(李林达);  Ding QH(丁奇寒);  Zhou J(周瑾);  Wu Y(武亿);  Zhang MK(张明坤);  Guo XM;  Long M(龙勉);  Lv SQ(吕守芹)
Adobe PDF(5539Kb)  |  收藏  |  浏览/下载:275/79  |  提交时间:2022/01/12
binding epitope  binding kinetics  CD44  selectin  
Tunable and Contamination-Free Injection with Microfluidics by Stepinjection 期刊论文
ANALYTICAL CHEMISTRY, 2021, 卷号: 93, 期号: 39, 页码: 13112-13117
作者:  Hu, BY;  Ye, S;  Chen, DW;  Xie, BL;  Hu, R;  Qiao, YX;  Yu, YH;  Yu, HY;  Zheng X(郑旭);  Lan, Y;  Du, WB
Adobe PDF(5316Kb)  |  收藏  |  浏览/下载:200/72  |  提交时间:2021/11/15
Multi-scale molecular dynamics simulations and applications on mechanosensitive proteins of integrins* 期刊论文
CHINESE PHYSICS B, 2021, 卷号: 30, 期号: 3, 页码: 8
作者:  Lv SQ(吕守芹);  Ding QH(丁奇寒);  Zhang MK(张明坤);  Long M(龙勉)
Adobe PDF(834Kb)  |  收藏  |  浏览/下载:272/86  |  提交时间:2021/04/19
molecular dynamics simulations  mechanosensitive protein  allosteric dynamics  integrin  
Characterizing liver sinusoidal endothelial cell fenestrae on soft substrates upon AFM imaging and deep learning 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2020, 卷号: 1864, 期号: 12, 页码: 9
作者:  Li PW(李培文);  Zhou J(周瑾);  Li W(李旺);  Wu H(吴欢);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Lv SQ(吕守芹);  Pan J;  Zhang CY;  Li N(李宁);  Long M(龙勉)
Adobe PDF(4976Kb)  |  收藏  |  浏览/下载:662/381  |  提交时间:2020/11/30
Liver sinusoidal endothelial cells  Fenestrae  Atomic force microscopy  Imaging recognition  Fully convolutional networks  Substrate stiffness  
Mechanically Regulated Outside-In Activation of an I-Domain-Containing Integrin 期刊论文
BIOPHYSICAL JOURNAL, 2020, 卷号: 119, 期号: 5, 页码: 966-977
作者:  Mao DB(毛德斌);  Lv SQ(吕守芹);  Zhang X(张潇);  Long M(龙勉)
Adobe PDF(2480Kb)  |  收藏  |  浏览/下载:240/65  |  提交时间:2020/10/29
Auto Micro Atomization Delivery of Human Epidermal Organoids Improves Therapeutic Effects for Skin Wound Healing 期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2020, 卷号: 8, 页码: 16
作者:  Chang MY;  Liu J;  Guo BL;  Fang X(方新);  Wang Y;  Wang SY;  Liu XF;  Reid LM;  Wang YF
Adobe PDF(2360Kb)  |  收藏  |  浏览/下载:189/70  |  提交时间:2020/05/18
cell delivery  auto micro atomization device (AMAD)  cell therapy  wound healing  organoids  
Intercellular Receptor-Ligand Binding and Thermal Fluctuations Facilitate Receptor Aggregation in Adhering Membranes 期刊论文
NANO LETTERS, 2020, 卷号: 20, 期号: 1, 页码: 722-728
作者:  Li L(李龙);  Hu JL;  Rozycki B;  Song F(宋凡)
Adobe PDF(2314Kb)  |  收藏  |  浏览/下载:294/90  |  提交时间:2020/03/11
cell membrane  adhesion  receptor proteins  nanoscale lipid clusters  thermal fluctuations  Monte Carlo simulations  
Mechanical Point Loading Induces Cortex Stiffening and Actin Reorganization 期刊论文
BIOPHYSICAL JOURNAL, 2019, 卷号: 117, 期号: 8, 页码: 1405-1418
作者:  Hu JR(胡锦荣);  Chen SB(陈深宝);  Hu WH(胡文慧);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(4950Kb)  |  收藏  |  浏览/下载:387/73  |  提交时间:2019/11/26