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IMECH-IR
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Simulated pathogenic conformational switch regions matched well with the biochemical findings 期刊论文
Journal of Biomedical Informatics., 2010, 卷号: 43, 期号: 3, 页码: 365-375
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥)
Adobe PDF(2010Kb)  |  收藏  |  浏览/下载：796/240  |  提交时间：2010/05/12
Switch Region for Pathogenic Structural Change in Conformational Disease and Its Prediction 期刊论文
PLoS One, 2010, 卷号: 5, 期号: 1, 页码: e8441
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥);  Zhao YP(赵亚溥)
浏览  |  Adobe PDF(670Kb)  |  收藏  |  浏览/下载：916/205  |  提交时间：2010/05/12
Generating artificial homologous proteins according to the representative family character in molecular mechanics properties - an attempt in validating an underlying rule of protein evolution 期刊论文
FEBS Letters, 2010, 卷号: 584, 期号: 5, 页码: 1059-1065
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥);  Zhao YP(赵亚溥)
浏览  |  Adobe PDF(895Kb)  |  收藏  |  浏览/下载：747/209  |  提交时间：2010/05/12
Donut-Shaped Fingerprint In Homologous Polypeptide Relationships-A Topological Feature Related To Pathogenic Structural Changes In Conformational Disease 期刊论文
Journal of Theoretical Biology, 2009, 卷号: 258, 期号: 2, 页码: 294-301
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥);  Zhao YP
Adobe PDF(513Kb)  |  收藏  |  浏览/下载：735/168  |  提交时间：2009/08/03
Homologous Relationship  Polypeptide  Prion Protein  Conformational Disease  Predicting Signal Peptides  State Enzyme-kinetics  Protein-structure  Graphic Rules  Codon Usage  Rate Laws  Evolution  Steady  Model  Prion  
A scheme for multiple sequences alignment optimization-an improvement based on family representative mechanics features 期刊论文
Journal of Theoretical Biology, 2009, 卷号: 261, 期号: 4, 页码: 593-597
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥)
浏览  |  Adobe PDF(493Kb)  |  收藏  |  浏览/下载：647/159  |  提交时间：2009/12/28
Scoring Scheme  Hydrophobic Interaction  Multiple Sequence Alignment  Homologous Proteins