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Fluid Flow-Induced Calcium Response in Osteoclasts: Signaling Pathways 期刊论文
ANNALS OF BIOMEDICAL ENGINEERING, 2014, 卷号: 42, 期号: 6, 页码: 1250-1260
作者:  Li, Ping;  Liu, Chenglin;  Hu, Man;  Long, Mian;  Zhang, Ding;  Huo, Bo;  Zhang, D (reprint author), Chinese Acad Med Sci, Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Stomatol,Fac Surg, Beijing 100730, Peoples R China.
浏览  |  Adobe PDF(2294Kb)  |  收藏  |  浏览/下载:715/237  |  提交时间:2014/06/19
Osteoclasts  Fluid Shear Stress  Calcium Response  Signaling Pathway  Differentiation  
Spreading area and shape regulate apoptosis and differentiation of osteoblasts 期刊论文
BIOMEDICAL MATERIALS, 2013, 卷号: 8, 期号: 5, 页码: 055005/1-055005/8
作者:  Fu RR(付瑞荣);  Liu QL(刘琴丽);  Song GB;  Baik A;  Hu M(胡漫);  Sun SJ(孙树津);  Guo XE;  Long M(龙勉);  Huo B(霍波);  Long, M (reprint author), Chinese Acad Sci, Key Lab Micrograv, Inst Mech, Beijing 100190, Peoples R China.
Adobe PDF(941Kb)  |  收藏  |  浏览/下载:891/236  |  提交时间:2013/10/28
Calcium response in osteocytic networks under steady and oscillatory fluid flow 期刊论文
BONE, 2012, 卷号: 51, 期号: 3, 页码: 466-473
作者:  Lu XL;  Huo B(霍波);  Park M;  Guo XE;  Guo, XE;  Columbia Univ, Dept Biomed Engn, Bone Bioengn Lab, 351 Engn Terrace,1210 Amsterdam Ave, New York, NY 10027 USA.
Adobe PDF(931Kb)  |  收藏  |  浏览/下载:889/347  |  提交时间:2013/01/18
Osteocyte  Mechanotransduction  Calcium Response  Fluid Flow  Steady  Oscillatory  Nitric-oxide Synthase  Bone Cell Mechanotransduction  Functional Gap-junctions  Osteoblastic Cells  Shear-stress  Mc3t3-e1 Osteoblasts  Molecular Regulation  Mlo-y4 Osteocytes  Mechanical Strain  Atp Release  
Osteocytic network is more responsive in calcium signaling than osteoblastic network under fluid flow 期刊论文
JOURNAL OF BONE AND MINERAL RESEARCH, 2012, 卷号: 27, 期号: 3, 页码: 563-574
作者:  Lu XL;  Huo B(霍波);  Chiang V;  Guo XE;  Guo, XE;  Columbia Univ, Dept Biomed Engn, Bone Bioenn Lab, 351 Engn Terrace,Mail Code 8904,1210 Amsterdam Av, New York, NY 10027 USA.
Adobe PDF(467Kb)  |  收藏  |  浏览/下载:955/210  |  提交时间:2013/01/18
Osteocytes  Osteoblasts  Cell Network  Mechanotransduction  Fluid Flow  Calcium Signaling  Functional Gap-junctions  Bone Cell Networks  Mc3t3-e1 Osteoblasts  Nitric-oxide  Shear-stress  Prostaglandin Release  Mlo-y4 Osteocytes  Ca2++ Channels  Atp Release  Long Bones  
Molecular dynamics simulation of shear- and stretch-induced dissociation of P-selectin/PSGL-1 complex 期刊论文
BIOPHYSICAL JOURNAL, 2012, 卷号: 102, 期号: 1, 页码: 112-120
作者:  Kang YY(康英永);  Lv SQ(吕守芹);  Ren P(任鹏);  Huo B(霍波);  Long M(龙勉);  Huo, B (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100080, Peoples R China.
Adobe PDF(1143Kb)  |  收藏  |  浏览/下载:960/197  |  提交时间:2013/01/18
Selectin Glycoprotein Ligand-1  Granule Membrane-protein  P-selectin  Cell-adhesion  Beta-switch  Endothelial-cells  Catch Bonds  Ib-alpha  Flow  Transition  
Fluid Dynamics Analysis of a Novel Micropatterned Cell Bioreactor 期刊论文
Annals of Biomedical Engineering, 2011, 卷号: 39, 期号: 5, 页码: 1592-1605
作者:  Cui YH;  Huo B(霍波);  Sun SJ(孙树津);  Yang F(杨帆);  Gao YX(高宇欣);  Pan J;  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100190, Peoples R China
Adobe PDF(1354Kb)  |  收藏  |  浏览/下载:989/189  |  提交时间:2012/04/01
Fluid Dynamics  Cell Bioreactor  Micropattern  Steady Shear-stress  Endothelial-cells  Flow  Mechanotransduction  Environment  Prediction  Scaffolds  Adhesion  Chamber  Systems  
Quasi-3D Cytoskeletal Dynamics of Osteocytes under Fluid Flow 期刊论文
Biophysical Journal, 2010, 卷号: 99, 期号: 9, 页码: 2812-2820
作者:  Baik AD;  Lu XL;  Qiu J;  Huo B(霍波);  Hillman EMC;  Dong C;  Guo XE;  Huo B
Adobe PDF(1028Kb)  |  收藏  |  浏览/下载:1193/190  |  提交时间:2011/03/01
Living Endothelial-cells  Viscoelastic Properties  Articular-cartilage  Shear-stress  Bone-cells  In-vitro  Adhesion  Deformation  Prestress  Strain  
A semi-3D real-time imaging technique for measuring bone cell deformation under fluid flow 会议论文
11th ASME Summer Bioengineering Conference, SBC2009, Lake Tahoe, CA, United states, June 17, 2009 - June 21, 2009
作者:  Baik AD;  Lu XL;  Huo B(霍波);  Liu XS;  Dong C;  Guo XE;  Baik, A. D.
浏览  |  Adobe PDF(218Kb)  |  收藏  |  浏览/下载:167/45  |  提交时间:2017/07/14
SMD simulations of shear loading induced dissociation of P-selectin/PSGL-1 complex 会议论文
3rd International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2009, Beijing, China, June 11, 2009 - June 13, 2009
作者:  Ren P;  Lv SQ(吕守芹);  Kang YY(康英永);  Huo B(霍波);  Long M(龙勉);  Long, M. (mlong@imech.ac.cn)
浏览  |  Adobe PDF(2535Kb)  |  收藏  |  浏览/下载:225/81  |  提交时间:2017/07/14
Atomic Levels  Blood Cells  Dissociation Process  Flow Direction  Functional Units  Inclination Angles  Induced Dissociation  Lec  Molecular Complexes  Molecular Mechanism  Rolling Process  Selectin  Selectins  Shear Fields  Shear Loadings  Shear Velocities  Simulation Result  Structural Basis  Water Molecule  
Parametric Analysis for Monitoring 2D Kinetics of Receptor-Ligand binding 期刊论文
Cellular and Molecular Bioengineering, 2009, 卷号: 2, 期号: 4, 页码: 495-503
作者:  Sun GY(孙淦云);  Zhang Y(章燕);  Huo B(霍波);  Long M(龙勉)
Adobe PDF(1749Kb)  |  收藏  |  浏览/下载:838/212  |  提交时间:2009/12/30