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Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization 期刊论文
SCIENCE ADVANCES, 2021, 卷号: 7, 期号: 42, 页码: 14
作者:  Zhang, KH;  Cloonan, PE.;  Sundaram, S;  Liu F(刘峰);  Das, SL;  Ewoldt, JK;  Bays, JL;  Tomp, S;  Toepfer, CN;  Marsiglia, JDC;  Gorham, J;  Reichart, D;  Eyckmans, J;  Seidman, JG;  Seidman, CE;  Chen, CS
Adobe PDF(1131Kb)  |  收藏  |  浏览/下载:241/57  |  提交时间:2021/11/15
Multi-scale molecular dynamics simulations and applications on mechanosensitive proteins of integrins* 期刊论文
CHINESE PHYSICS B, 2021, 卷号: 30, 期号: 3, 页码: 8
作者:  Lv SQ(吕守芹);  Ding QH(丁奇寒);  Zhang MK(张明坤);  Long M(龙勉)
Adobe PDF(834Kb)  |  收藏  |  浏览/下载:271/85  |  提交时间:2021/04/19
molecular dynamics simulations  mechanosensitive protein  allosteric dynamics  integrin  
Mechanically Regulated Outside-In Activation of an I-Domain-Containing Integrin 期刊论文
BIOPHYSICAL JOURNAL, 2020, 卷号: 119, 期号: 5, 页码: 966-977
作者:  Mao DB(毛德斌);  Lv SQ(吕守芹);  Zhang X(张潇);  Long M(龙勉)
Adobe PDF(2480Kb)  |  收藏  |  浏览/下载:239/65  |  提交时间:2020/10/29
Mechanomics analysis of hESCs under combined mechanical shear, stretch, and compression 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2020, 页码: 18
作者:  Zhang F(张帆);  Wang JW(王家文);  Lv DY(吕东媛);  Zheng L(郑璐);  Shang GB(上官冰);  Gao YX(高宇欣);  Wu Y(武亿);  Long M(龙勉)
Adobe PDF(8050Kb)  |  收藏  |  浏览/下载:312/168  |  提交时间:2020/10/23
Mechanomics  hESCs  iTRAQ  GSEA  WGCNA  
Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
作者:  Shu XY(舒芯钰);  Li N(李宁);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
浏览  |  Adobe PDF(1108Kb)  |  收藏  |  浏览/下载:451/168  |  提交时间:2020/04/07
beta(2) integrin  Ligands  Calcium transients  Bond strength  Mechanotransduction  Shear stress  
Microgravity-induced hepatogenic differentiation of rBMSCs on board the SJ-10 satellite 期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 3, 页码: 4273-4286
作者:  Lv DY(吕东媛);  Sun SJ(孙树津);  Zhang F(张帆);  Luo CH(罗春花);  Zheng L;  Wu Y(武毅);  Li N(李宁);  Zhang C;  Wang CZ;  Chen Q;  Long M(龙勉)
浏览  |  Adobe PDF(3477Kb)  |  收藏  |  浏览/下载:302/97  |  提交时间:2019/04/11
mesenchymal stem cells  mechanotransduction  hepatocyte  signaling pathway  
Computational model of wound healing: EGF secreted by fibroblasts promotes delayed re-epithelialization of epithelial keratinocytes 期刊论文
INTEGRATIVE BIOLOGY, 2018, 卷号: 10, 期号: 10, 页码: 605-634
作者:  Andasari V;  Lv DY(吕东媛);  Swat M;  Feng SL(冯世亮);  Spill F;  Chen L;  Luo XD;  Zaman M;  Long M(龙勉)
浏览  |  Adobe PDF(12579Kb)  |  收藏  |  浏览/下载:265/101  |  提交时间:2019/05/30
Dynamic seesaw model for rapid signaling responses in eukaryotic chemotaxis 期刊论文
PHYSICAL BIOLOGY, 2018, 卷号: 15, 期号: 5
作者:  Feng SL;  Zhou LW(周吕文);  Lv SQ(吕守芹);  Zhang Y(章燕)
浏览  |  Adobe PDF(1669Kb)  |  收藏  |  浏览/下载:321/77  |  提交时间:2018/07/17
Polarization  Signaling Cascade  Mathematical Model  Lattice-boltzmann Method  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
作者:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
浏览  |  Adobe PDF(865Kb)  |  收藏  |  浏览/下载:395/192  |  提交时间:2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Conformational folding and disulfide bonding drive distinct stages of protein structure formation 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 页码: 1494
作者:  Lv JM;  Lv SQ(吕守芹);  Liu ZP;  Zhang J;  Gao BoX;  Yao ZY;  Wu YX;  Potempa LA.;  Ji SR;  Long M(龙勉);  Wu Y(武毅)
浏览  |  Adobe PDF(5071Kb)  |  收藏  |  浏览/下载:263/69  |  提交时间:2018/07/17