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Two Complementary Signaling Pathways Depict Eukaryotic Chemotaxis: A Mechanochemical Coupling Model 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9, 页码: 12
作者:  Zhou LW(周吕文);  Feng SL(冯世亮);  Li L(李龙);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(2763Kb)  |  收藏  |  浏览/下载:212/41  |  提交时间:2022/01/13
chemotaxis  cytoskeletal remodeling  mathematical model  biochemical  biomechanical  
E-selectin negatively regulates polymorphonuclear neutrophil transmigration through altered endothelial junction integrity 期刊论文
FASEB JOURNAL, 2021, 卷号: 35, 期号: 5, 页码: 15
作者:  Huang DD(黄丹丹);  Ding QH(丁奇寒);  Chen SB(陈深宝);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(2008Kb)  |  收藏  |  浏览/下载:255/75  |  提交时间:2021/08/03
cytoskeletal remodeling  endothelial integrity  E-selectin  neutrophil  transmigration  
Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
作者:  Shu XY(舒芯钰);  Li N(李宁);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
浏览  |  Adobe PDF(1108Kb)  |  收藏  |  浏览/下载:434/162  |  提交时间:2020/04/07
beta(2) integrin  Ligands  Calcium transients  Bond strength  Mechanotransduction  Shear stress  
Mechanical features of endothelium regulate cell adhesive molecule-induced calcium response in neutrophils 期刊论文
APL BIOENGINEERING, 2019, 卷号: 3, 期号: 1, 页码: 16104
作者:  Xu YH(徐艳红);  Huang DD(黄丹丹);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(5460Kb)  |  收藏  |  浏览/下载:102/14  |  提交时间:2022/10/25
Mechanochemical modeling of neutrophil migration based on four signaling layers, integrin dynamics, and substrate stiffness 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2018, 卷号: 17, 期号: 6, 页码: 1611-1630
作者:  Feng SL(冯世亮);  Zhou LW(周吕文);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(3483Kb)  |  收藏  |  浏览/下载:396/136  |  提交时间:2019/05/30
Chemotaxis  Cytoskeletal remodeling  Mathematical model  Biochemical  Biomechanical  
Dynamic seesaw model for rapid signaling responses in eukaryotic chemotaxis 期刊论文
PHYSICAL BIOLOGY, 2018, 卷号: 15, 期号: 5
作者:  Feng SL;  Zhou LW(周吕文);  Lv SQ(吕守芹);  Zhang Y(章燕)
Adobe PDF(1669Kb)  |  收藏  |  浏览/下载:313/77  |  提交时间:2018/07/17
Polarization  Signaling Cascade  Mathematical Model  Lattice-boltzmann Method  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
作者:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
Adobe PDF(865Kb)  |  收藏  |  浏览/下载:387/188  |  提交时间:2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling 期刊论文
MOLECULAR BIOLOGY OF THE CELL, 2018, 卷号: 29, 期号: 4, 页码: 408-418
作者:  Li N(李宁);  Yang H(杨浩);  Wang ML;  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(1832Kb)  |  收藏  |  浏览/下载:401/94  |  提交时间:2018/10/30
Dynamic contributions of P- and E-selectins to beta(2)-integrin-induced neutrophil transmigration 期刊论文
FASEB JOURNAL, 2017, 卷号: 31, 期号: 1, 页码: 212-+
作者:  Gong YX;  Zhang Y(章燕);  Feng SL;  Liu XF;  Lv SQ(吕守芹);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Ctr Biomech & Bioengn, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.;  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Natl Micrograv Lab, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
Adobe PDF(2514Kb)  |  收藏  |  浏览/下载:576/243  |  提交时间:2017/04/26
Mechanokinetics of receptor-ligand interactions in cell adhesion 期刊论文
Acta Mechanica Sinica, 2015, 卷号: 31, 期号: 2, 页码: 248-258
作者:  Li N(李宁);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Ctr Biomech & Bioengn, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100190, Peoples R China.
Adobe PDF(809Kb)  |  收藏  |  浏览/下载:529/160  |  提交时间:2015/07/21
Receptor-ligand Interactions  Selectins  Beta(2) Integrins  2d Binding Kinetics