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Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer 期刊论文
ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448
作者:  Li N(李宁);  Zhang XY(张晓宇);  Zhou J(周瑾);  Li W(李旺);  Shu XY(舒芯钰);  Wu Y(武亿);  Long M(龙勉)
Adobe PDF(2553Kb)  |  收藏  |  浏览/下载：333/94  |  提交时间：2022/10/23
Liver tissue stiffness  Shear stress  Hydrostatic pressure  Hepatocytes  Hepatocellular carcinoma  Liver sinusoidal endothelial cells  Hepatic stellate cells  Mechanotransduction pathways  Mechanomedicine  Drug design and delivery  
Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
作者:  Shu XY(舒芯钰);  Li N(李宁);  Wu Y(武亿);  Li W(李旺);  Zhang XY(张晓宇);  Li PW(李培文);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1359Kb)  |  收藏  |  浏览/下载：380/106  |  提交时间：2021/05/06
Liver sinusoidal endothelial cell  Shear stress  Mechanical stretch  Extracellular matrix  Stiffness  
Flow field analyses of a porous membrane-separated, double-layered microfluidic chip for cell co-culture 期刊论文
ACTA MECHANICA SINICA, 2020, 页码: 14
作者:  Chen SB(陈深宝);  Xue J(薛健);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Zhou LW(周吕文);  Feng SL(冯世亮);  Cui YH;  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(5919Kb)  |  收藏  |  浏览/下载：285/131  |  提交时间：2020/08/26
Immersed boundary method  Porous membrane  Wall shear stress  Penetration velocity  Microfluidic chip  
Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
作者:  Shu XY(舒芯钰);  Li N(李宁);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
浏览  |  Adobe PDF(1108Kb)  |  收藏  |  浏览/下载：453/168  |  提交时间：2020/04/07
beta(2) integrin  Ligands  Calcium transients  Bond strength  Mechanotransduction  Shear stress  
Fluid Flow-Induced Calcium Response in Osteoclasts: Signaling Pathways 期刊论文
ANNALS OF BIOMEDICAL ENGINEERING, 2014, 卷号: 42, 期号: 6, 页码: 1250-1260
作者:  Li, Ping;  Liu, Chenglin;  Hu, Man;  Long, Mian;  Zhang, Ding;  Huo, Bo;  Zhang, D (reprint author), Chinese Acad Med Sci, Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Stomatol,Fac Surg, Beijing 100730, Peoples R China.
浏览  |  Adobe PDF(2294Kb)  |  收藏  |  浏览/下载：724/240  |  提交时间：2014/06/19
Osteoclasts  Fluid Shear Stress  Calcium Response  Signaling Pathway  Differentiation  
Fluid flow-induced calcium response in early or late differentiated osteoclasts 期刊论文
ANNALS OF BIOMEDICAL ENGINEERING, 2012, 卷号: 40, 期号: 9, 页码: 1874-1883
作者:  Li P(李平);  Hu M(胡漫);  Sun SJ(孙树津);  Zhang Y(章燕);  Gao YX(高宇欣);  Long M(龙勉);  Huo B(霍波);  Zhang D;  Huo, B;  Chinese Acad Sci, Inst Mech, Ctr Biomech & Bioengn, Key Lab Micrograv, 15 N 4th Ring Rd, Beijing 100190, Peoples R China.
Adobe PDF(887Kb)  |  收藏  |  浏览/下载：1214/347  |  提交时间：2013/01/18
Osteoclasts  Fluid Shear Stress  Calcium Oscillation  Induction Time  Differentiation  Mechanical Strain  Rat Osteoclasts  Bone-resorption  Activation  Expression  Cells  Ca2++  
Spreading of human neutrophils on an ICAM-1-immobilized substrate under shear flow 期刊论文
CHINESE SCIENCE BULLETIN, 2012, 卷号: 57, 期号: 7, 页码: 769-775
作者:  Zhan DY(展冬颖);  Zhang Y(章燕);  Long M(龙勉);  Long, MA;  Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100190, Peoples R China.
Adobe PDF(685Kb)  |  收藏  |  浏览/下载：979/230  |  提交时间：2013/01/18
Neutrophil  Spreading  Beta 2 Integrin  Icam-1  Shear Stress  Cell-surface Adhesion  L-selectin  Polymorphonuclear Leukocytes  Endothelial-cells  Rolling Adhesions  P-selectin  Integrin  Affinity  Stress  Icam-1  
Advances in Experiments and Modeling in Micro- and Nano-Biomechanics: A Mini Review 期刊论文
Cellular and Molecular Bioengineering, 2011, 卷号: 4, 期号: 3, 页码: 327-339
作者:  Long M(龙勉);  Sato M;  Lim CT;  Wu JH;  Adachi T;  Inoue Y;  Long, M (reprint author), Chinese Acad Sci, Key Lab Micrograv, Ctr Biomech & Bioengn, Inst Mech, Beijing 100190, Peoples R China
Adobe PDF(2481Kb)  |  收藏  |  浏览/下载：1614/338  |  提交时间：2012/04/01
Cellular Mechanics  Molecular Biomechanics  Experimental Techniques  Theoretical Modeling  Computations  Fluid Shear-stress  Endothelial-cell Proliferation  Adhesive Dynamics Simulation  Ligand Binding-kinetics  Glycoprotein-ib-alpha  Von-willebrand-factor  Molecular-dynamics  Mechanical-stress  Beta-switch  2-dimensional Kinetics  
Fluid Dynamics Analysis of a Novel Micropatterned Cell Bioreactor 期刊论文
Annals of Biomedical Engineering, 2011, 卷号: 39, 期号: 5, 页码: 1592-1605
作者:  Cui YH;  Huo B(霍波);  Sun SJ(孙树津);  Yang F(杨帆);  Gao YX(高宇欣);  Pan J;  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100190, Peoples R China
Adobe PDF(1354Kb)  |  收藏  |  浏览/下载：998/192  |  提交时间：2012/04/01
Fluid Dynamics  Cell Bioreactor  Micropattern  Steady Shear-stress  Endothelial-cells  Flow  Mechanotransduction  Environment  Prediction  Scaffolds  Adhesion  Chamber  Systems  
A Novel Counter Sheet-Flow Sandwich Cell Culture Device For Mammalian Cell Growth In Space 期刊论文
Microgravity Science And Technology, 2008, 页码: 115-120
作者:  Sun SJ(孙树津);  Gao YX(高宇欣);  Shu NJ;  Tang ZM(唐泽眉);  Tao ZL(陶祖莱);  Long M(龙勉);  Sun, SJ (reprint author), Chinese Acad Sci, Inst Mech, Natl Micrograv Lab, Beijing 100190, Peoples R China.
Adobe PDF(238Kb)  |  收藏  |  浏览/下载：882/179  |  提交时间：2009/08/03
Counter Sheet-flow Sandwich Cell Culture  Mammalian Cell Growth  Microgravity  Dogfish Scyliorhinus Stellaris  Shear-stress  Spaceflight  Microgravity  Bioreactors  Exchange  Gills  Blood  Water  Wall