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Distinct binding kinetics of E-, P- and L-selectins to CD44 期刊论文
FEBS JOURNAL, 2022, 页码: 18
作者:  Li LD(李林达);  Ding QH(丁奇寒);  Zhou J(周瑾);  Wu Y(武亿);  Zhang MK(张明坤);  Guo XM;  Long M(龙勉);  Lv SQ(吕守芹)
Adobe PDF(5539Kb)  |  收藏  |  浏览/下载:261/74  |  提交时间:2022/01/12
binding epitope  binding kinetics  CD44  selectin  
E-selectin negatively regulates polymorphonuclear neutrophil transmigration through altered endothelial junction integrity 期刊论文
FASEB JOURNAL, 2021, 卷号: 35, 期号: 5, 页码: 15
作者:  Huang DD(黄丹丹);  Ding QH(丁奇寒);  Chen SB(陈深宝);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(2008Kb)  |  收藏  |  浏览/下载:255/75  |  提交时间:2021/08/03
cytoskeletal remodeling  endothelial integrity  E-selectin  neutrophil  transmigration  
Impact of real-time shedding on binding kinetics of membrane-remaining L-selectin to PSGL-1 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2019, 卷号: 316, 期号: 5, 页码: C678-C689
作者:  Peng S(彭爽);  Chen SB(陈深宝);  Li LD(李林达);  Tong CF(佟春芳);  Li N(李宁);  Lv SQ(吕守芹);  Long M(龙勉)
浏览  |  Adobe PDF(2200Kb)  |  收藏  |  浏览/下载:385/198  |  提交时间:2019/12/02
binding kinetics  competitive binding  L-selectin  modeling  real-time shedding  
Spring constant regulate selectin-ligand bond dissociation 期刊论文
医用生物力学, 2013, 期号: S1, 页码: 95-96
作者:  Zhang Y(章燕);  Sun GY(孙淦云);  Lv SQ(吕守芹);  Long M(龙勉)
浏览  |  Adobe PDF(128Kb)  |  收藏  |  浏览/下载:264/47  |  提交时间:2015/09/02
Selectin  Dissociation  Rupture  Kinetics  Landscape  Metastasis  Regulate  Quantify  Leukocyte  Unclear  
Spring constant regulate selectin-ligand bond dissociation 会议论文
第五届中美生物医学工程暨海内外生物力学学术研讨会, 中国北京/Beijing, China, 2013-08-01
作者:  Zhang Y(章燕);  Sun GY(孙淦云);  Lv SQ(吕守芹);  Long M(龙勉)
浏览  |  Adobe PDF(91Kb)  |  收藏  |  浏览/下载:476/117  |  提交时间:2014/04/02
Dissociation  Regulate  Selectin  Constant  Formation  Further  Increased  Stiffness  Lifetime  Ligand  Binding  Assay  Probe  Force  Kinetics  Mainly  Reverse  Values  Well  Found  
Spreading of human neutrophils on an ICAM-1-immobilized substrate under shear flow 期刊论文
CHINESE SCIENCE BULLETIN, 2012, 卷号: 57, 期号: 7, 页码: 769-775
作者:  Zhan DY(展冬颖);  Zhang Y(章燕);  Long M(龙勉);  Long, MA;  Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100190, Peoples R China.
Adobe PDF(685Kb)  |  收藏  |  浏览/下载:968/227  |  提交时间:2013/01/18
Neutrophil  Spreading  Beta 2 Integrin  Icam-1  Shear Stress  Cell-surface Adhesion  L-selectin  Polymorphonuclear Leukocytes  Endothelial-cells  Rolling Adhesions  P-selectin  Integrin  Affinity  Stress  Icam-1  
Molecular dynamics simulation of shear- and stretch-induced dissociation of P-selectin/PSGL-1 complex 期刊论文
BIOPHYSICAL JOURNAL, 2012, 卷号: 102, 期号: 1, 页码: 112-120
作者:  Kang YY(康英永);  Lv SQ(吕守芹);  Ren P(任鹏);  Huo B(霍波);  Long M(龙勉);  Huo, B (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100080, Peoples R China.
Adobe PDF(1143Kb)  |  收藏  |  浏览/下载:960/197  |  提交时间:2013/01/18
Selectin Glycoprotein Ligand-1  Granule Membrane-protein  P-selectin  Cell-adhesion  Beta-switch  Endothelial-cells  Catch Bonds  Ib-alpha  Flow  Transition  
Determining beta(2)-Integrin and Intercellular Adhesion Molecule 1 Binding Kinetics in Tumor Cell Adhesion to Leukocytes and Endothelial Cells by a Gas-driven Micropipette Assay 期刊论文
Journal of Biological Chemistry, 2011, 卷号: 286, 期号: 40, 页码: 34777-34787
作者:  Fu ZL(傅长亮);  Tong CF(佟春芳);  Wang ML;  Gao YX(高宇欣);  Zhang Y(章燕);  Lv SQ(吕守芹);  Liang SL;  Dong C;  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100190, Peoples R China
Adobe PDF(1888Kb)  |  收藏  |  浏览/下载:1302/230  |  提交时间:2012/04/01
Mammary Adenocarcinoma Cells  Hydrodynamic Shear  Melanoma Adhesion  2-dimensional Kinetics  Human Neutrophils  P-selectin  Metastasis Development  Ligand Interactions  Concurrent Binding  Cancer Metastasis  
Probe stiffness regulates receptor-ligand bond lifetime under force 期刊论文
Science China-Physics Mechanics & Astronomy, 2011, 卷号: 54, 期号: 5, 页码: 923-929
作者:  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100190, Peoples R China
Adobe PDF(534Kb)  |  收藏  |  浏览/下载:1332/249  |  提交时间:2012/04/01
Probe Stiffness  Bond Lifetime  Optical Trap  Selectin Glycoprotein Ligand-1  P-selectin  Cell-adhesion  Binding-kinetics  Leukocytes  Molecule  Psgl-1  Flow  
SMD simulations of shear loading induced dissociation of P-selectin/PSGL-1 complex 会议论文
3rd International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2009, Beijing, China, June 11, 2009 - June 13, 2009
作者:  Ren P;  Lv SQ(吕守芹);  Kang YY(康英永);  Huo B(霍波);  Long M(龙勉);  Long, M. (mlong@imech.ac.cn)
浏览  |  Adobe PDF(2535Kb)  |  收藏  |  浏览/下载:226/82  |  提交时间:2017/07/14
Atomic Levels  Blood Cells  Dissociation Process  Flow Direction  Functional Units  Inclination Angles  Induced Dissociation  Lec  Molecular Complexes  Molecular Mechanism  Rolling Process  Selectin  Selectins  Shear Fields  Shear Loadings  Shear Velocities  Simulation Result  Structural Basis  Water Molecule