IMECH-IR  > 非线性力学国家重点实验室
Tunable rigidity of (polymeric core)-(lipid shell) nanoparticles for regulated cellular uptake
Sun JS(孙佳姝); Zhang L(张璐); Wang JL(王九令); Feng Q(冯强); Liu DB; Yin QF(殷其放); Xu DY; Wei YJ(魏宇杰); Ding BQ(丁宝全); Shi XH(施兴华); Jiang XY(蒋兴宇); Shi XH(施兴华)
Source PublicationAdvanced Materials
2014-12-22
Volume25Issue:8Pages:1402-1407
ISSN0935-9648
Abstract

Core-shell nanoparticles (NPs) with lipid shells and varying water content and rigidity but with the same chemical composition, size, and surface properties are assembled using a microfluidic platform. Rigidity can dramatically alter the cellular uptake efficiency, with more-rigid NPs able to pass more easily through cell membranes. The mechanism accounting for this rigidity-dependent cellular uptake is revealed through atomistic-level simulations.

KeywordMicrofluidics Core–shell Nanoparticles Biomedical Applications Cellular Uptake Drug Delivery
Subject Area固体力学 ; 生物力学
DOI10.1002/adma.201404788
URL查看原文
Indexed BySCI ; EI
Language英语
WOS IDWOS:000350058200015
DepartmentLNM微结构计算力学(筹)
Classification一类
Citation statistics
Document Type期刊论文
Identifierhttp://dspace.imech.ac.cn/handle/311007/49407
Collection非线性力学国家重点实验室
Corresponding AuthorShi XH(施兴华)
Recommended Citation
GB/T 7714
Sun JS,Zhang L,Wang JL,et al. Tunable rigidity of (polymeric core)-(lipid shell) nanoparticles for regulated cellular uptake[J]. Advanced Materials,2014,25(8):1402-1407.
APA Sun JS.,Zhang L.,Wang JL.,Feng Q.,Liu DB.,...&施兴华.(2014).Tunable rigidity of (polymeric core)-(lipid shell) nanoparticles for regulated cellular uptake.Advanced Materials,25(8),1402-1407.
MLA Sun JS,et al."Tunable rigidity of (polymeric core)-(lipid shell) nanoparticles for regulated cellular uptake".Advanced Materials 25.8(2014):1402-1407.
Files in This Item: Download All
File Name/Size DocType Version Access License
adma201404788.pdf(1876KB)期刊论文出版稿开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Sun JS(孙佳姝)]'s Articles
[Zhang L(张璐)]'s Articles
[Wang JL(王九令)]'s Articles
Baidu academic
Similar articles in Baidu academic
[Sun JS(孙佳姝)]'s Articles
[Zhang L(张璐)]'s Articles
[Wang JL(王九令)]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Sun JS(孙佳姝)]'s Articles
[Zhang L(张璐)]'s Articles
[Wang JL(王九令)]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: adma201404788.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.