Multi-layer composite mechanical modeling for the inhomogeneous biofilm mechanical behavior

doi:10.1142/S0219720016500141

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	Multi-layer composite mechanical modeling for the inhomogeneous biofilm mechanical behavior
	Wang XL; Han JS; Li K; Wang GQ; Hao MD; Wang, XL (reprint author), Univ Sci & Technol Beijing, Sch Mech Engn, Beijing 100083, Peoples R China.; Wang, XL (reprint author), Harvard Univ, Fac Arts & Sci, Harvard John A Paulson Sch Engn & Appl Sci, Cambridge, MA 02138 USA.; Wang, XL (reprint author), Chinese Acad Sci, LNM, Inst Mech, 15 Bei Si Huan Xi Lu, Beijing 100190, Peoples R China.
发表期刊	JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY
	2016
卷号	14 期号:4 页码:1650014
ISSN	0219-7200
摘要	Experiments showed that bacterial biofilms are heterogeneous, for example, the density, the diffusion coefficient, and mechanical properties of the biofilm are different along the biofilm thickness. In this paper, we establish a multi-layer composite model to describe the biofilm mechanical inhomogeneity based on unified multiple-component cellular automaton (UMCCA) model. By using our model, we develop finite element simulation procedure for biofilm tension experiment. The failure limit and biofilm extension displacement obtained from our model agree well with experimental measurements. This method provides an alternative theory to study the mechanical inhomogeneity in biological materials.
关键词	Biofilm Finite Element Method Multi-layer Composite Mechanical Model Umcca Inhomogeneity
DOI	10.1142/S0219720016500141
URL	查看原文
收录类别	SCI
语种	英语
WOS记录号	WOS:000384031700003
关键词[WOS]	Biofilm ; finite element method ; multi-layer composite mechanical model ; UMCCA ; inhomogeneity
WOS研究方向	Biochemistry & Molecular Biology ; Computer Science ; Mathematical & Computational Biology
WOS类目	Biochemical Research Methods ; Computer Science, Interdisciplinary Applications ; Mathematical & Computational Biology
项目资助者	The work was supported by Harvard University, the National Natural Science Foundation of China (Grant No. 11272002), Opening fund of State Key Laboratory of Nonlinear Mechanics, and Beijing Higher Education Young Elite Teacher Project (Grant No. YETP0363).
论文分区	Q4
力学所作者排名	False
引用统计	被引频次：7[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://dspace.imech.ac.cn/handle/311007/59729
专题	非线性力学国家重点实验室
通讯作者	Wang, XL (reprint author), Univ Sci & Technol Beijing, Sch Mech Engn, Beijing 100083, Peoples R China.; Wang, XL (reprint author), Harvard Univ, Fac Arts & Sci, Harvard John A Paulson Sch Engn & Appl Sci, Cambridge, MA 02138 USA.; Wang, XL (reprint author), Chinese Acad Sci, LNM, Inst Mech, 15 Bei Si Huan Xi Lu, Beijing 100190, Peoples R China.
推荐引用方式 GB/T 7714	Wang XL,Han JS,Li K,et al. Multi-layer composite mechanical modeling for the inhomogeneous biofilm mechanical behavior[J]. JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY,2016,14,4,:1650014.
APA	Wang XL.,Han JS.,Li K.,Wang GQ.,Hao MD.,...&Wang, XL .(2016).Multi-layer composite mechanical modeling for the inhomogeneous biofilm mechanical behavior.JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY,14(4),1650014.
MLA	Wang XL,et al."Multi-layer composite mechanical modeling for the inhomogeneous biofilm mechanical behavior".JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY 14.4(2016):1650014.

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