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Binding of different hyaluronan to CD44 mediates distinct cell adhesion dynamics under shear flow 期刊论文
FEBS JOURNAL, 2023
Authors:  Li LD(李林达);  Ding QH(丁奇寒);  Wu Y(武亿);  Zheng Z(郑植);  Zhang XN(张晓宁);  Zhang MK(张明焜);  Long M(龙勉);  Lv SQ(吕守芹)
Adobe PDF(6108Kb)  |  Favorite  |  View/Download:67/3  |  Submit date:2023/07/17
CD44  HA  molecular weight  shear flow  two-dimensional interaction  
Distinct binding kinetics of E-, P- and L-selectins to CD44 期刊论文
FEBS JOURNAL, 2022, 页码: 18
Authors:  Li LD(李林达);  Ding QH(丁奇寒);  Zhou J(周瑾);  Wu Y(武亿);  Zhang MK(张明坤);  Guo XM;  Long M(龙勉);  Lv SQ(吕守芹)
Adobe PDF(5539Kb)  |  Favorite  |  View/Download:308/86  |  Submit date:2022/01/12
binding epitope  binding kinetics  CD44  selectin  
A Novel Human Antibody, HF, against HER2/erb-B2 Obtained by a Computer-Aided Antibody Design Method 期刊论文
ENGINEERING, 2021, 卷号: 7, 期号: 11, 页码: 1566-1576
Authors:  Qiao, Chunxia;  Lv, Ming;  Li, Xinying;  Lang, Xiaoling;  Lv SQ(吕守芹);  Long M(龙勉);  Li, Yan;  Geng, Shusheng;  Lin, Zhou;  Shen, Beifen;  Feng, Jiannan
Adobe PDF(4174Kb)  |  Favorite  |  View/Download:214/39  |  Submit date:2022/02/17
HER2/erb-B2  Human antibody  Computer-aided design  
E-selectin negatively regulates polymorphonuclear neutrophil transmigration through altered endothelial junction integrity 期刊论文
FASEB JOURNAL, 2021, 卷号: 35, 期号: 5, 页码: 15
Authors:  Huang DD(黄丹丹);  Ding QH(丁奇寒);  Chen SB(陈深宝);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(2008Kb)  |  Favorite  |  View/Download:282/88  |  Submit date:2021/08/03
cytoskeletal remodeling  endothelial integrity  E-selectin  neutrophil  transmigration  
Multi-scale molecular dynamics simulations and applications on mechanosensitive proteins of integrins* 期刊论文
CHINESE PHYSICS B, 2021, 卷号: 30, 期号: 3, 页码: 8
Authors:  Lv SQ(吕守芹);  Ding QH(丁奇寒);  Zhang MK(张明坤);  Long M(龙勉)
Adobe PDF(834Kb)  |  Favorite  |  View/Download:297/91  |  Submit date:2021/04/19
molecular dynamics simulations  mechanosensitive protein  allosteric dynamics  integrin  
CD44-配体相互作用的生物力学与功能调控 期刊论文
力学学报, 2021, 卷号: 53, 期号: 02, 页码: 539-553
Authors:  李林达;  丁奇寒;  陈深宝;  吕守芹;  龙勉;  郭兴明
Adobe PDF(796Kb)  |  Favorite  |  View/Download:436/103  |  Submit date:2021/04/19
CD44  选择素  透明质酸  细胞粘附  力学调控  炎症反应  
Mechanically Regulated Outside-In Activation of an I-Domain-Containing Integrin 期刊论文
BIOPHYSICAL JOURNAL, 2020, 卷号: 119, 期号: 5, 页码: 966-977
Authors:  Mao DB(毛德斌);  Lv SQ(吕守芹);  Zhang X(张潇);  Long M(龙勉)
Adobe PDF(2480Kb)  |  Favorite  |  View/Download:262/71  |  Submit date:2020/10/29
Global mapping of live cell mechanical features usingPeakForce QNM AFM 期刊论文
Biophysics Reports, 2020, 卷号: 6, 期号: 1, 页码: 9-18
Authors:  Hu JR(胡锦荣);  Chen SB(陈深宝);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(2838Kb)  |  Favorite  |  View/Download:202/57  |  Submit date:2021/01/29
Impact of real-time shedding on binding kinetics of membrane-remaining L-selectin to PSGL-1 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2019, 卷号: 316, 期号: 5, 页码: C678-C689
Authors:  Peng S(彭爽);  Chen SB(陈深宝);  Li LD(李林达);  Tong CF(佟春芳);  Li N(李宁);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(2200Kb)  |  Favorite  |  View/Download:419/213  |  Submit date:2019/12/02
binding kinetics  competitive binding  L-selectin  modeling  real-time shedding  
Mechanochemical modeling of neutrophil migration based on four signaling layers, integrin dynamics, and substrate stiffness 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2018, 卷号: 17, 期号: 6, 页码: 1611-1630
Authors:  Feng SL(冯世亮);  Zhou LW(周吕文);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(3483Kb)  |  Favorite  |  View/Download:432/153  |  Submit date:2019/05/30
Chemotaxis  Cytoskeletal remodeling  Mathematical model  Biochemical  Biomechanical