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Trail Formation Alleviates Excessive Adhesion and Maintains Efficient Neutrophil Migration 期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2023
Authors:  Hu WH(胡文慧);  Gao WB(高文博);  Gong YX(龚一心);  Guo P(郭盼);  Li W(李旺);  Shu XY(舒芯钰);  Lv SQ(吕守芹);  Zeng, Zhu;  Zhang Y(章燕);  Long M(龙勉)
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neutrophil migration  trail release  rear contraction  fi2 integrin  cell adhesion  
Mechanical features of endothelium regulate cell adhesive molecule-induced calcium response in neutrophils 期刊论文
APL BIOENGINEERING, 2019, 卷号: 3, 期号: 1, 页码: 16104
Authors:  Xu YH(徐艳红);  Huang DD(黄丹丹);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
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Mechanochemical modeling of neutrophil migration based on four signaling layers, integrin dynamics, and substrate stiffness 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2018, 卷号: 17, 期号: 6, 页码: 1611-1630
Authors:  Feng SL(冯世亮);  Zhou LW(周吕文);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(3483Kb)  |  Favorite  |  View/Download:422/147  |  Submit date:2019/05/30
Chemotaxis  Cytoskeletal remodeling  Mathematical model  Biochemical  Biomechanical  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
Authors:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
View  |  Adobe PDF(865Kb)  |  Favorite  |  View/Download:418/197  |  Submit date:2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Distinct kinetics features of LFA-1 and Mac-1 in neutrophil activation 会议论文
World Congress on Medical Physics and Biomedical Engineering, Beijing, China, MAY 26-31, 2012
Authors:  Li N(李宁);  Mao DB(毛德斌);  Gong YX(龚一心);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
View  |  Adobe PDF(944Kb)  |  Favorite  |  View/Download:610/154  |  Submit date:2014/03/04
Lfa-1  Mac-1  Icam-1  On-rate  Off-rate  
Fluid flow-induced calcium response in early or late differentiated osteoclasts 期刊论文
ANNALS OF BIOMEDICAL ENGINEERING, 2012, 卷号: 40, 期号: 9, 页码: 1874-1883
Authors:  Li P(李平);  Hu M(胡漫);  Sun SJ(孙树津);  Zhang Y(章燕);  Gao YX(高宇欣);  Long M(龙勉);  Huo B(霍波);  Zhang D;  Huo, B;  Chinese Acad Sci, Inst Mech, Ctr Biomech & Bioengn, Key Lab Micrograv, 15 N 4th Ring Rd, Beijing 100190, Peoples R China.
Adobe PDF(887Kb)  |  Favorite  |  View/Download:1224/356  |  Submit date:2013/01/18
Osteoclasts  Fluid Shear Stress  Calcium Oscillation  Induction Time  Differentiation  Mechanical Strain  Rat Osteoclasts  Bone-resorption  Activation  Expression  Cells  Ca2++  
Probe stiffness regulates receptor-ligand bond lifetime under force 期刊论文
Science China-Physics Mechanics & Astronomy, 2011, 卷号: 54, 期号: 5, 页码: 923-929
Authors:  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100190, Peoples R China
Adobe PDF(534Kb)  |  Favorite  |  View/Download:1368/261  |  Submit date:2012/04/01
Probe Stiffness  Bond Lifetime  Optical Trap  Selectin Glycoprotein Ligand-1  P-selectin  Cell-adhesion  Binding-kinetics  Leukocytes  Molecule  Psgl-1  Flow  
Force spectroscopy of single receptor-ligand bond using an optical trap 会议论文
2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009, Shanghai, China, November 2, 2009 - November 6, 2009
Authors:  Zhang Y(章燕);  Sun GY(孙淦云);  Li N(李宁);  Huo B(霍波);  Lv SQ(吕守芹);  Long M(龙勉);  Zhang, Y.
View  |  Adobe PDF(2190Kb)  |  Favorite  |  View/Download:122/43  |  Submit date:2017/07/14
Bond Dissociation  Force Spectroscopy  Low Loading  Novel Methods  Optical Trap  Receptor-ligand Bonds  Receptor-ligand Interactions  Thermal Fluctuations  Unbinding Transitions  
Quantifying rupture force and bond lifetime of P-selectin-PSGL-1 interactions at lower forces 会议论文
Advances in Heterogeneous Material Mechanics 2008 - 2nd International Conference on Heterogeneous Material Mechanics, ICHMM 2008, Huangshan, China, June 3, 2008 - June 8, 2008
Authors:  Zhang Y(章燕);  Sun GY(孙淦云);  Huo B(霍波);  Long M(龙勉)
Favorite  |  View/Download:114/0  |  Submit date:2017/06/01
Applied Forces  Atomic Forces  Biological Processes  Bond Dissociations  Bond Lifetimes  Bond Ruptures  External Forces  Flow Chambers  Glycoprotein Ligands  Life-times  Ligand Interactions  Loading Rates  Optical Traps  Physiological Flows  Rupture Forces  Selectin  Spring Constants  Thrombosis Formations  To Many  Tumor Metastases  
应用光阱技术测量P-selectin/PSGL-1键解离的断裂力 期刊论文
生物医学工程学杂志, 2005, 卷号: 22, 期号: 5, 页码: 961-965
Authors:  章燕;  叶志义;  霍波;  孙淦云;  龙勉
Adobe PDF(392Kb)  |  Favorite  |  View/Download:798/334  |  Submit date:2007/06/15
光阱  刚度系数  P-selectin/psgl-1键  断裂力