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Real-time structural signatures of protein allostery by electrically- and mechanically-coupled sensing 期刊论文
NANO TODAY, 2024, 卷号: 55, 页码: 10
Authors:  Zhang, Mingkun;  Zheng, Zhi;  Zhou, Jin;  Ding, Qihan;  Long, Mian;  Lue, Shouqin
Favorite  |  View/Download:21/0  |  Submit date:2024/03/25
Nanopore sensing  Atomic force microscopy (AFM)  Protein allostery  Steered molecular dynamics (SMD)  Spheroid approximation  
基于纳米孔传感的蛋白质构象动力学特征研究 学位论文
博士论文,北京: 中国科学院大学, 2023
Authors:  张明焜
Adobe PDF(9719Kb)  |  Favorite  |  View/Download:85/2  |  Submit date:2024/01/19
纳米孔传感,αXβ2整合素,分子动力学,回转椭球体近似,拉伸分子动力学  
细胞贯穿孔洞形成与稳定的分子动力学模拟 学位论文
硕士论文,北京: 中国科学院大学, 2023
Authors:  郑植
Adobe PDF(7142Kb)  |  Favorite  |  View/Download:111/2  |  Submit date:2023/06/25
细胞贯穿孔洞  肝血窦内皮细胞  跨内皮细胞大孔  膜融合  粗粒化分 子动力学模拟  膜张力  稳定性  
Distinct binding kinetics of E-, P- and L-selectins to CD44 期刊论文
FEBS JOURNAL, 2022, 页码: 18
Authors:  Li LD(李林达);  Ding QH(丁奇寒);  Zhou J(周瑾);  Wu Y(武亿);  Zhang MK(张明坤);  Guo XM;  Long M(龙勉);  Lv SQ(吕守芹)
Adobe PDF(5539Kb)  |  Favorite  |  View/Download:284/81  |  Submit date:2022/01/12
binding epitope  binding kinetics  CD44  selectin  
Multi-scale molecular dynamics simulations and applications on mechanosensitive proteins of integrins* 期刊论文
CHINESE PHYSICS B, 2021, 卷号: 30, 期号: 3, 页码: 8
Authors:  Lv SQ(吕守芹);  Ding QH(丁奇寒);  Zhang MK(张明坤);  Long M(龙勉)
Adobe PDF(834Kb)  |  Favorite  |  View/Download:278/88  |  Submit date:2021/04/19
molecular dynamics simulations  mechanosensitive protein  allosteric dynamics  integrin  
Mechanically Regulated Outside-In Activation of an I-Domain-Containing Integrin 期刊论文
BIOPHYSICAL JOURNAL, 2020, 卷号: 119, 期号: 5, 页码: 966-977
Authors:  Mao DB(毛德斌);  Lv SQ(吕守芹);  Zhang X(张潇);  Long M(龙勉)
Adobe PDF(2480Kb)  |  Favorite  |  View/Download:247/66  |  Submit date:2020/10/29
Conformational folding and disulfide bonding drive distinct stages of protein structure formation 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 页码: 1494
Authors:  Lv JM;  Lv SQ(吕守芹);  Liu ZP;  Zhang J;  Gao BoX;  Yao ZY;  Wu YX;  Potempa LA.;  Ji SR;  Long M(龙勉);  Wu Y(武毅)
View  |  Adobe PDF(5071Kb)  |  Favorite  |  View/Download:267/69  |  Submit date:2018/07/17
Salt bridge interactions within the beta(2) integrin alpha(7) helix mediate force-induced binding and shear resistance ability 期刊论文
FEBS JOURNAL, 2018, 卷号: 285, 期号: 2, 页码: 261-274
Authors:  Zhang X(张潇);  Li LD;  Li N(李宁);  Shu XY;  Zhou LW(周吕文);  Lv SQ(吕守芹);  Chen SB;  Mao DB;  Long M(龙勉)
View  |  Adobe PDF(2053Kb)  |  Favorite  |  View/Download:249/67  |  Submit date:2018/10/30
beta(2) integrin  allostery  conformational stability  force  salt bridge interaction  
β2整合素变构动力学模拟 学位论文
博士论文,北京: 中国科学院大学, 2017
Authors:  张潇
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Distinct Kinetics Features of LFA-1 and Mac-1 in Neutrophil Activation 期刊论文
Chinese Journal of Biomedical Engineering, 2015, 卷号: 24, 期号: 1, 页码: 40-46
Authors:  Li N(李宁);  Mao DB(毛德斌);  Gong YX(龚一心);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
View  |  Adobe PDF(1792Kb)  |  Favorite  |  View/Download:297/96  |  Submit date:2017/08/16