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Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Wu Y(武亿);  Li W(李旺);  Zhang XY(张晓宇);  Li PW(李培文);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Long M(龙勉)
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Liver sinusoidal endothelial cell  Shear stress  Mechanical stretch  Extracellular matrix  Stiffness  
CD44-配体相互作用的生物力学与功能调控 期刊论文
力学学报, 2021, 卷号: 53, 期号: 02, 页码: 539-553
Authors:  李林达;  丁奇寒;  陈深宝;  吕守芹;  龙勉;  郭兴明
Adobe PDF(796Kb)  |  Favorite  |  View/Download：418/97  |  Submit date：2021/04/19
CD44  选择素  透明质酸  细胞粘附  力学调控  炎症反应  
Mechanically Regulated Outside-In Activation of an I-Domain-Containing Integrin 期刊论文
BIOPHYSICAL JOURNAL, 2020, 卷号: 119, 期号: 5, 页码: 966-977
Authors:  Mao DB(毛德斌);  Lv SQ(吕守芹);  Zhang X(张潇);  Long M(龙勉)
Adobe PDF(2480Kb)  |  Favorite  |  View/Download：254/69  |  Submit date：2020/10/29
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
Authors:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
View  |  Adobe PDF(865Kb)  |  Favorite  |  View/Download：413/195  |  Submit date：2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Distinct kinetics features of LFA-1 and Mac-1 in neutrophil activation 会议论文
World Congress on Medical Physics and Biomedical Engineering, Beijing, China, MAY 26-31, 2012
Authors:  Li N(李宁);  Mao DB(毛德斌);  Gong YX(龚一心);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(944Kb)  |  Favorite  |  View/Download：605/151  |  Submit date：2014/03/04
Lfa-1  Mac-1  Icam-1  On-rate  Off-rate  
Probe stiffness regulates receptor-ligand bond lifetime under force 期刊论文
Science China-Physics Mechanics & Astronomy, 2011, 卷号: 54, 期号: 5, 页码: 923-929
Authors:  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100190, Peoples R China
Adobe PDF(534Kb)  |  Favorite  |  View/Download：1363/258  |  Submit date：2012/04/01
Probe Stiffness  Bond Lifetime  Optical Trap  Selectin Glycoprotein Ligand-1  P-selectin  Cell-adhesion  Binding-kinetics  Leukocytes  Molecule  Psgl-1  Flow  
SMD simulations of shear loading induced dissociation of P-selectin/PSGL-1 complex 会议论文
3rd International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2009, Beijing, China, June 11, 2009 - June 13, 2009
Authors:  Ren P;  Lv SQ(吕守芹);  Kang YY(康英永);  Huo B(霍波);  Long M(龙勉);  Long, M. (mlong@imech.ac.cn)
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Atomic Levels  Blood Cells  Dissociation Process  Flow Direction  Functional Units  Inclination Angles  Induced Dissociation  Lec  Molecular Complexes  Molecular Mechanism  Rolling Process  Selectin  Selectins  Shear Fields  Shear Loadings  Shear Velocities  Simulation Result  Structural Basis  Water Molecule  
Forced Dissociation of Selectin-ligand Complexes Using Steered Molecular Dynamics Simulation 期刊论文
MCB, 2005, 卷号: 2, 期号: 4, 页码: 161-177
Authors:  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(620Kb)  |  Favorite  |  View/Download：738/172  |  Submit date：2007/06/15