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Real-time structural signatures of protein allostery by electrically- and mechanically-coupled sensing 期刊论文
NANO TODAY, 2024, 卷号: 55, 页码: 10
作者:  Zhang, Mingkun;  Zheng, Zhi;  Zhou, Jin;  Ding, Qihan;  Long, Mian;  Lue, Shouqin
收藏  |  浏览/下载:10/0  |  提交时间:2024/03/25
Nanopore sensing  Atomic force microscopy (AFM)  Protein allostery  Steered molecular dynamics (SMD)  Spheroid approximation  
FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17
作者:  Zhang XY(张晓宇);  Li PW(李培文);  Zhou J(周瑾);  Zhang ZL(张子良);  Wu H(吴欢);  Shu XY(舒芯钰);  Li W(李旺);  Wu Y(武亿);  Du Y(杜宇);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
收藏  |  浏览/下载:11/0  |  提交时间:2024/04/02
Liver sinusoidal endothelial cells  Fenestrae  Liver fibrosis  Cytoskeleton remodeling  FAK  MAPK  
Splitting of fast relaxation in a metallic glass by laser shocks 期刊论文
PHYSICAL REVIEW B, 2024, 卷号: 109, 期号: 2, 页码: 8
作者:  Yang C(杨成);  Duan J(段军);  Ding G(丁淦);  Bai YJ(白云建);  Wei BC(魏炳忱);  Wei YP(魏延鹏);  Liu, SN;  Lan, S;  Zhang, BB;  Shi, CJ;  Dai LH(戴兰宏);  Jiang MQ(蒋敏强)
收藏  |  浏览/下载:10/0  |  提交时间:2024/04/29
Binding of different hyaluronan to CD44 mediates distinct cell adhesion dynamics under shear flow 期刊论文
FEBS JOURNAL, 2023
作者:  Li LD(李林达);  Ding QH(丁奇寒);  Wu Y(武亿);  Zheng Z(郑植);  Zhang XN(张晓宁);  Zhang MK(张明焜);  Long M(龙勉);  Lv SQ(吕守芹)
Adobe PDF(6108Kb)  |  收藏  |  浏览/下载:58/0  |  提交时间:2023/07/17
CD44  HA  molecular weight  shear flow  two-dimensional interaction  
剪切应力及基质硬度调控肝细胞功能的生物力学机制 学位论文
博士论文,北京: 中国科学院大学, 2023
作者:  李旺
Adobe PDF(8757Kb)  |  收藏  |  浏览/下载:246/6  |  提交时间:2023/06/26
剪切应力  基质硬度  增殖  肝细胞特异性功能  力学转导  
力学拉伸调控肝血窦内皮细胞旁分泌及信号转导机制 学位论文
博士论文,北京: 中国科学院大学, 2023
作者:  武亿
Adobe PDF(31496Kb)  |  收藏  |  浏览/下载:109/3  |  提交时间:2023/07/06
肝再生  力学拉伸  肝血窦内皮细胞  旁分泌  信号转导  
Potential Roles of YAP/TAZ Mechanotransduction in Spaceflight-Induced Liver Dysfunction 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 3, 页码: 20
作者:  Li W(李旺);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang ZL(张子良);  Sun SJ(孙树津);  Li N(李宁);  Long M(龙勉)
Adobe PDF(1498Kb)  |  收藏  |  浏览/下载:118/0  |  提交时间:2023/03/20
microgravity  liver metabolism  mechanosensing  cytoskeleton  nuclear deformation  phase separation  
A regime beyond the Hall-Petch and inverse-Hall-Petch regimes in ultrafine-grained solids 期刊论文
COMMUNICATIONS PHYSICS, 2022, 卷号: 5, 期号: 1, 页码: 9
作者:  Zhang, Huijun;  Liu, Feng;  Ungar, Goran;  Zheng ZY(郑中玉);  Sun, Qingping;  Han, Yilong
Adobe PDF(3619Kb)  |  收藏  |  浏览/下载:163/32  |  提交时间:2023/02/20
Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis 期刊论文
BIOACTIVE MATERIALS, 2022, 卷号: 17, 页码: 406-424
作者:  Wang, Jin;  Xie, Si-an;  Li N(李宁);  Zhang, Tao;  Yao, Weijuan;  Zhao, Hucheng;  Pang, Wei;  Han, Lili;  Liu, Jiayu;  Zhou, Jing
Adobe PDF(21819Kb)  |  收藏  |  浏览/下载:275/23  |  提交时间:2022/06/10
Matrix stiffness  Inflammation  DDR1  DNMT1  Mechanotransduction  
Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer 期刊论文
ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448
作者:  Li N(李宁);  Zhang XY(张晓宇);  Zhou J(周瑾);  Li W(李旺);  Shu XY(舒芯钰);  Wu Y(武亿);  Long M(龙勉)
Adobe PDF(2553Kb)  |  收藏  |  浏览/下载:327/91  |  提交时间:2022/10/23
Liver tissue stiffness  Shear stress  Hydrostatic pressure  Hepatocytes  Hepatocellular carcinoma  Liver sinusoidal endothelial cells  Hepatic stellate cells  Mechanotransduction pathways  Mechanomedicine  Drug design and delivery