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Real-time structural signatures of protein allostery by electrically- and mechanically-coupled sensing 期刊论文
NANO TODAY, 2024, 卷号: 55, 页码: 10
作者:  Zhang, Mingkun;  Zheng, Zhi;  Zhou, Jin;  Ding, Qihan;  Long, Mian;  Lue, Shouqin
收藏  |  浏览/下载:11/0  |  提交时间:2024/03/25
Nanopore sensing  Atomic force microscopy (AFM)  Protein allostery  Steered molecular dynamics (SMD)  Spheroid approximation  
Distinct binding kinetics of E-, P- and L-selectins to CD44 期刊论文
FEBS JOURNAL, 2022, 页码: 18
作者:  Li LD(李林达);  Ding QH(丁奇寒);  Zhou J(周瑾);  Wu Y(武亿);  Zhang MK(张明坤);  Guo XM;  Long M(龙勉);  Lv SQ(吕守芹)
Adobe PDF(5539Kb)  |  收藏  |  浏览/下载:264/75  |  提交时间:2022/01/12
binding epitope  binding kinetics  CD44  selectin  
Two Complementary Signaling Pathways Depict Eukaryotic Chemotaxis: A Mechanochemical Coupling Model 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9, 页码: 12
作者:  Zhou LW(周吕文);  Feng SL(冯世亮);  Li L(李龙);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(2763Kb)  |  收藏  |  浏览/下载:219/42  |  提交时间:2022/01/13
chemotaxis  cytoskeletal remodeling  mathematical model  biochemical  biomechanical  
Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
作者:  Shu XY(舒芯钰);  Li N(李宁);  Wu Y(武亿);  Li W(李旺);  Zhang XY(张晓宇);  Li PW(李培文);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1359Kb)  |  收藏  |  浏览/下载:374/102  |  提交时间:2021/05/06
Liver sinusoidal endothelial cell  Shear stress  Mechanical stretch  Extracellular matrix  Stiffness  
Multi-scale molecular dynamics simulations and applications on mechanosensitive proteins of integrins* 期刊论文
CHINESE PHYSICS B, 2021, 卷号: 30, 期号: 3, 页码: 8
作者:  Lv SQ(吕守芹);  Ding QH(丁奇寒);  Zhang MK(张明坤);  Long M(龙勉)
Adobe PDF(834Kb)  |  收藏  |  浏览/下载:268/84  |  提交时间:2021/04/19
molecular dynamics simulations  mechanosensitive protein  allosteric dynamics  integrin  
Mechanically Regulated Outside-In Activation of an I-Domain-Containing Integrin 期刊论文
BIOPHYSICAL JOURNAL, 2020, 卷号: 119, 期号: 5, 页码: 966-977
作者:  Mao DB(毛德斌);  Lv SQ(吕守芹);  Zhang X(张潇);  Long M(龙勉)
Adobe PDF(2480Kb)  |  收藏  |  浏览/下载:233/63  |  提交时间:2020/10/29
Epidermal restriction confers robustness to organ shapes 期刊论文
JOURNAL OF INTEGRATIVE PLANT BIOLOGY, 2020, 页码: 15
作者:  Zhou LW(周吕文);  Du F;  Feng SL(冯世亮);  Hu JR(胡锦荣);  Lv SQ(吕守芹);  Long M(龙勉);  Jiao YL
Adobe PDF(8113Kb)  |  收藏  |  浏览/下载:220/60  |  提交时间:2020/10/29
Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
作者:  Shu XY(舒芯钰);  Li N(李宁);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1108Kb)  |  收藏  |  浏览/下载:441/165  |  提交时间:2020/04/07
beta(2) integrin  Ligands  Calcium transients  Bond strength  Mechanotransduction  Shear stress  
Biomechanical stress regulates mammalian tooth replacement via the integrin beta 1-RUNX2-Wnt pathway 期刊论文
EMBO JOURNAL, 2020, 卷号: 39, 期号: 3, 页码: 19
作者:  Wu XS;  Hu JR(胡锦荣);  Li GQ;  Li Y;  Li Y;  Zhang J;  Wang F;  Li A;  Hu L;  Fan ZP;  Lv SQ(吕守芹);  Ding G;  Zhang CM;  Wang JS;  Long M(龙勉);  Wang SL
Adobe PDF(7490Kb)  |  收藏  |  浏览/下载:238/64  |  提交时间:2020/03/11
biomechanics  organ replacement  stress  Wnt signaling  
Impact of real-time shedding on binding kinetics of membrane-remaining L-selectin to PSGL-1 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2019, 卷号: 316, 期号: 5, 页码: C678-C689
作者:  Peng S(彭爽);  Chen SB(陈深宝);  Li LD(李林达);  Tong CF(佟春芳);  Li N(李宁);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(2200Kb)  |  收藏  |  浏览/下载:387/199  |  提交时间:2019/12/02
binding kinetics  competitive binding  L-selectin  modeling  real-time shedding