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Two Complementary Signaling Pathways Depict Eukaryotic Chemotaxis: A Mechanochemical Coupling Model 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9, 页码: 12
作者:  Zhou LW(周吕文);  Feng SL(冯世亮);  Li L(李龙);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(2763Kb)  |  收藏  |  浏览/下载:211/41  |  提交时间:2022/01/13
chemotaxis  cytoskeletal remodeling  mathematical model  biochemical  biomechanical  
E-selectin negatively regulates polymorphonuclear neutrophil transmigration through altered endothelial junction integrity 期刊论文
FASEB JOURNAL, 2021, 卷号: 35, 期号: 5, 页码: 15
作者:  Huang DD(黄丹丹);  Ding QH(丁奇寒);  Chen SB(陈深宝);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(2008Kb)  |  收藏  |  浏览/下载:255/75  |  提交时间:2021/08/03
cytoskeletal remodeling  endothelial integrity  E-selectin  neutrophil  transmigration  
Mapping the morphological identifiers of distinct conformations via the protein translocation current in nanopores 期刊论文
NANOSCALE, 2021, 卷号: 13, 期号: 12, 页码: 14
作者:  Zhang MK(张明坤);  Chen SB(陈深宝);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Li LD(李林达);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(6632Kb)  |  收藏  |  浏览/下载:314/53  |  提交时间:2021/05/17
CD44-配体相互作用的生物力学与功能调控 期刊论文
力学学报, 2021, 卷号: 53, 期号: 02, 页码: 539-553
作者:  李林达;  丁奇寒;  陈深宝;  吕守芹;  龙勉;  郭兴明
Adobe PDF(796Kb)  |  收藏  |  浏览/下载:372/87  |  提交时间:2021/04/19
CD44  选择素  透明质酸  细胞粘附  力学调控  炎症反应  
Binding of intercellular adhesion molecule 1 to beta(2)-integrin regulates distinct cell adhesion processes on hepatic and cerebral endothelium 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2018, 卷号: 315, 期号: 3, 页码: C409-C421
作者:  Tong CF(佟春芳);  Zhang Y(章燕);  Lv SQ(吕守芹);  Li N(李宁);  Gong YX(龚一心);  Yang H;  Feng SL;  Du Y;  Huang DD;  Long M(龙勉)
浏览  |  Adobe PDF(1593Kb)  |  收藏  |  浏览/下载:548/269  |  提交时间:2018/10/30
brain  ICAM-1  integrin  kinetics  liver  
Dynamic seesaw model for rapid signaling responses in eukaryotic chemotaxis 期刊论文
PHYSICAL BIOLOGY, 2018, 卷号: 15, 期号: 5
作者:  Feng SL;  Zhou LW(周吕文);  Lv SQ(吕守芹);  Zhang Y(章燕)
浏览  |  Adobe PDF(1669Kb)  |  收藏  |  浏览/下载:313/77  |  提交时间:2018/07/17
Polarization  Signaling Cascade  Mathematical Model  Lattice-boltzmann Method  
Salt bridge interactions within the beta(2) integrin alpha(7) helix mediate force-induced binding and shear resistance ability 期刊论文
FEBS JOURNAL, 2018, 卷号: 285, 期号: 2, 页码: 261-274
作者:  Zhang X(张潇);  Li LD;  Li N(李宁);  Shu XY;  Zhou LW(周吕文);  Lv SQ(吕守芹);  Chen SB;  Mao DB;  Long M(龙勉)
浏览  |  Adobe PDF(2053Kb)  |  收藏  |  浏览/下载:240/64  |  提交时间:2018/10/30
beta(2) integrin  allostery  conformational stability  force  salt bridge interaction  
Determining beta(2)-Integrin and Intercellular Adhesion Molecule 1 Binding Kinetics in Tumor Cell Adhesion to Leukocytes and Endothelial Cells by a Gas-driven Micropipette Assay 期刊论文
Journal of Biological Chemistry, 2011, 卷号: 286, 期号: 40, 页码: 34777-34787
作者:  Fu ZL(傅长亮);  Tong CF(佟春芳);  Wang ML;  Gao YX(高宇欣);  Zhang Y(章燕);  Lv SQ(吕守芹);  Liang SL;  Dong C;  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100190, Peoples R China
Adobe PDF(1888Kb)  |  收藏  |  浏览/下载:1301/230  |  提交时间:2012/04/01
Mammary Adenocarcinoma Cells  Hydrodynamic Shear  Melanoma Adhesion  2-dimensional Kinetics  Human Neutrophils  P-selectin  Metastasis Development  Ligand Interactions  Concurrent Binding  Cancer Metastasis  
Low Spring Constant Regulates P-Selectin-Psgl-1 Bond Rupture 期刊论文
Biophysical Journal, 2008, 页码: 5439-5448
作者:  Zhang Y(章燕);  Sun GY(孙淦云);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Natl Micrograv Lab, Beijing 100190, Peoples R China.
Adobe PDF(634Kb)  |  收藏  |  浏览/下载:919/202  |  提交时间:2009/08/03
Selectin Glycoprotein Ligand-1  P-selectin  Cell-adhesion  Binding-kinetics  Force  Dissociation  Lifetime  Flow  Microscope  Leukocytes  
P-选择素/PSGL-1分子反应动力学和力作用下键解离的实验和分子动力学模拟 学位论文
博士论文,北京: 中国科学院研究生院, 2006
作者:  吕守芹
Adobe PDF(3977Kb)  |  收藏  |  浏览/下载:956/1  |  提交时间:2009/04/13