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Simulated pathogenic conformational switch regions matched well with the biochemical findings 期刊论文
Journal of Biomedical Informatics., 2010, 卷号: 43, 期号: 3, 页码: 365-375
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥)
Adobe PDF(2010Kb)  |  收藏  |  浏览/下载：790/237  |  提交时间：2010/05/12
Substitution Matrices of Residue Triplets Derived from Protein Blocks. 期刊论文
Journal of Computational Biology, 2010, 卷号: 17, 期号: 12, 页码: 1679
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥)
Adobe PDF(362Kb)  |  收藏  |  浏览/下载：815/213  |  提交时间：2010/12/21
hydrophobicity  Sequence Alignment  Twilight Zone.  
Switch Region for Pathogenic Structural Change in Conformational Disease and Its Prediction 期刊论文
PLoS One, 2010, 卷号: 5, 期号: 1, 页码: e8441
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥);  Zhao YP(赵亚溥)
浏览  |  Adobe PDF(670Kb)  |  收藏  |  浏览/下载：908/203  |  提交时间：2010/05/12
Generating artificial homologous proteins according to the representative family character in molecular mechanics properties - an attempt in validating an underlying rule of protein evolution 期刊论文
FEBS Letters, 2010, 卷号: 584, 期号: 5, 页码: 1059-1065
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥);  Zhao YP(赵亚溥)
浏览  |  Adobe PDF(895Kb)  |  收藏  |  浏览/下载：743/208  |  提交时间：2010/05/12
甲型H1N1/2009 流感病毒的种属跨越机制 期刊论文
中国科学C辑, 2009, 卷号: 39, 期号: 7, 页码: 643-646
作者:  刘鑫;  赵亚溥
Adobe PDF(875Kb)  |  收藏  |  浏览/下载：1643/554  |  提交时间：2009/12/28
Donut-Shaped Fingerprint In Homologous Polypeptide Relationships-A Topological Feature Related To Pathogenic Structural Changes In Conformational Disease 期刊论文
Journal of Theoretical Biology, 2009, 卷号: 258, 期号: 2, 页码: 294-301
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥);  Zhao YP
Adobe PDF(513Kb)  |  收藏  |  浏览/下载：727/165  |  提交时间：2009/08/03
Homologous Relationship  Polypeptide  Prion Protein  Conformational Disease  Predicting Signal Peptides  State Enzyme-kinetics  Protein-structure  Graphic Rules  Codon Usage  Rate Laws  Evolution  Steady  Model  Prion  
A scheme for multiple sequences alignment optimization-an improvement based on family representative mechanics features 期刊论文
Journal of Theoretical Biology, 2009, 卷号: 261, 期号: 4, 页码: 593-597
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥)
浏览  |  Adobe PDF(493Kb)  |  收藏  |  浏览/下载：644/158  |  提交时间：2009/12/28
Scoring Scheme  Hydrophobic Interaction  Multiple Sequence Alignment  Homologous Proteins  
Major factors of protein evolution revealed by eigenvalue decomposition analysis 会议论文
2008 International Conference on Bioinformatics and Computational Biology, BIOCOMP 2008, Las Vegas, NV, United states, July 14, 2008 - July 17, 2008
作者:  Liu X(刘鑫);  Zhang LM;  Yin J;  Zhao YP(赵亚溥)
浏览  |  Adobe PDF(1129Kb)  |  收藏  |  浏览/下载：99/18  |  提交时间：2017/06/01
Eigenvalue Decomposition Analysis  Hydrophobic Interaction  Protein Evolution  Remote Homologues  Sequence Analysis And Alignment  
Clemaps: Multiple Alignment Of Protein Structures Based On Conformational Letters 期刊论文
Proteins-Structure Function And Bioinformatics, 2008, 页码: 728-736
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥);  Zheng WM(郑伟谋);  Zheng, WM (reprint author), Acad Sinica, Inst Theoret Phys, Beijing 100080, Peoples R China.
Adobe PDF(567Kb)  |  收藏  |  浏览/下载：593/153  |  提交时间：2009/08/03
Protein Structure