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Characterizing liver sinusoidal endothelial cell fenestrae on soft substrates upon AFM imaging and deep learning 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2020, 卷号: 1864, 期号: 12, 页码: 9
作者:  Li PW(李培文);  Zhou J(周瑾);  Li W(李旺);  Wu H(吴欢);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Lv SQ(吕守芹);  Pan J;  Zhang CY;  Li N(李宁);  Long M(龙勉)
Adobe PDF(4976Kb)  |  收藏  |  浏览/下载：649/375  |  提交时间：2020/11/30
Liver sinusoidal endothelial cells  Fenestrae  Atomic force microscopy  Imaging recognition  Fully convolutional networks  Substrate stiffness  
Salt bridge interactions within the beta(2) integrin alpha(7) helix mediate force-induced binding and shear resistance ability 期刊论文
FEBS JOURNAL, 2018, 卷号: 285, 期号: 2, 页码: 261-274
作者:  Zhang X(张潇);  Li LD;  Li N(李宁);  Shu XY;  Zhou LW(周吕文);  Lv SQ(吕守芹);  Chen SB;  Mao DB;  Long M(龙勉)
浏览  |  Adobe PDF(2053Kb)  |  收藏  |  浏览/下载：241/64  |  提交时间：2018/10/30
beta(2) integrin  allostery  conformational stability  force  salt bridge interaction  
Spring constant regulate selectin-ligand bond dissociation 会议论文
第五届中美生物医学工程暨海内外生物力学学术研讨会, 中国北京/Beijing, China, 2013-08-01
作者:  Zhang Y(章燕);  Sun GY(孙淦云);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(91Kb)  |  收藏  |  浏览/下载：476/117  |  提交时间：2014/04/02
Dissociation  Regulate  Selectin  Constant  Formation  Further  Increased  Stiffness  Lifetime  Ligand  Binding  Assay  Probe  Force  Kinetics  Mainly  Reverse  Values  Well  Found  
Impact of probe stiffness on receptor-ligand bond dissociation 会议论文
the 3rd Asia Pacific Protein Association Conference in Conjunction with the 3rd Symposium of the Chinese Protein Society, 中国北京/Beijing, China, 2011-05-06
作者:  Zhang Y(章燕);  Sun GY(孙淦云);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(77Kb)  |  收藏  |  浏览/下载：346/80  |  提交时间：2014/04/02
Stiffness  Receptor  Dissociation  Ligand  Probe  Molecule  Probe  Formation  Force  Cario  Barrier  Determine  Metastasis  Mainly  Governed  Irreversible  Bonds  Theorem  Effect  Energy  
Surface-Bound Selectin-Ligand Binding Is Regulated By Carrier Diffusion 期刊论文
European Biophysics Journal With Biophysics Letters, 2009, 页码: 701-711
作者:  Sun GY(孙淦云);  Zhang Y(章燕);  Huo B(霍波);  Long M(龙勉);  Long M
Adobe PDF(559Kb)  |  收藏  |  浏览/下载：760/177  |  提交时间：2009/08/03
Association Kinetics  Regulating Factors  Carrier Diffusion  Optical Trap  Selectin  Ligand  Mediated Cell-adhesion  P-selectin  Glycoprotein Ligand-1  Optical Tweezers  Shear-flow  Human Neutrophils  Force Microscopy  Association Rate  Contact Area  Kinetics  
Force spectroscopy of single receptor-ligand bond using an optical trap 会议论文
2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009, Shanghai, China, November 2, 2009 - November 6, 2009
作者:  Zhang Y(章燕);  Sun GY(孙淦云);  Li N(李宁);  Huo B(霍波);  Lv SQ(吕守芹);  Long M(龙勉);  Zhang, Y.
浏览  |  Adobe PDF(2190Kb)  |  收藏  |  浏览/下载：110/36  |  提交时间：2017/07/14
Bond Dissociation  Force Spectroscopy  Low Loading  Novel Methods  Optical Trap  Receptor-ligand Bonds  Receptor-ligand Interactions  Thermal Fluctuations  Unbinding Transitions  
Low Spring Constant Regulates P-Selectin-Psgl-1 Bond Rupture 期刊论文
Biophysical Journal, 2008, 页码: 5439-5448
作者:  Zhang Y(章燕);  Sun GY(孙淦云);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Natl Micrograv Lab, Beijing 100190, Peoples R China.
Adobe PDF(634Kb)  |  收藏  |  浏览/下载：919/202  |  提交时间：2009/08/03
Selectin Glycoprotein Ligand-1  P-selectin  Cell-adhesion  Binding-kinetics  Force  Dissociation  Lifetime  Flow  Microscope  Leukocytes  
Kinetics of Receptor-Ligand Interactions in Immune Responses 期刊论文
CELLULAR & MOLECULAR IMMUNOLOGY, 2006, 卷号: 3, 期号: 2, 页码: 79-86
作者:  Long M(龙勉);  Lv SQ(吕守芹);  Sun GY(孙淦云);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Natl Micrograv Lab, Beijing 100080, Peoples R China.
浏览  |  Adobe PDF(524Kb)  |  收藏  |  浏览/下载：198/78  |  提交时间：2016/01/11
Kinetics  Force  Receptor-ligand Bond  Cell Adhesion