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| Binding of different hyaluronan to CD44 mediates distinct cell adhesion dynamics under shear flow 期刊论文 FEBS JOURNAL, 2023 作者: Li LD(李林达); Ding QH(丁奇寒); Wu Y(武亿); Zheng Z(郑植); Zhang XN(张晓宁); Zhang MK(张明焜); Long M(龙勉); Lv SQ(吕守芹) Adobe PDF(6108Kb)  |  收藏  |  浏览/下载:59/0  |  提交时间:2023/07/17 CD44 HA molecular weight shear flow two-dimensional interaction |
| Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer 期刊论文 ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448 作者: Li N(李宁); Zhang XY(张晓宇); Zhou J(周瑾); Li W(李旺); Shu XY(舒芯钰); Wu Y(武亿); Long M(龙勉) Adobe PDF(2553Kb)  |  收藏  |  浏览/下载:332/93  |  提交时间:2022/10/23 Liver tissue stiffness Shear stress Hydrostatic pressure Hepatocytes Hepatocellular carcinoma Liver sinusoidal endothelial cells Hepatic stellate cells Mechanotransduction pathways Mechanomedicine Drug design and delivery |
| Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文 ACTA MECHANICA SINICA, 2021, 页码: 17 作者: Shu XY(舒芯钰); Li N(李宁); Wu Y(武亿); Li W(李旺); Zhang XY(张晓宇); Li PW(李培文); Lv DY(吕东媛); Lv SQ(吕守芹); Long M(龙勉) Adobe PDF(1359Kb)  |  收藏  |  浏览/下载:377/104  |  提交时间:2021/05/06 Liver sinusoidal endothelial cell Shear stress Mechanical stretch Extracellular matrix Stiffness |
| Flow field analyses of a porous membrane-separated, double-layered microfluidic chip for cell co-culture 期刊论文 ACTA MECHANICA SINICA, 2020, 页码: 14 作者: Chen SB(陈深宝); Xue J(薛健); Hu JR(胡锦荣); Ding QH(丁奇寒); Zhou LW(周吕文); Feng SL(冯世亮); Cui YH; Lv SQ(吕守芹); Long M(龙勉) Adobe PDF(5919Kb)  |  收藏  |  浏览/下载:285/131  |  提交时间:2020/08/26 Immersed boundary method Porous membrane Wall shear stress Penetration velocity Microfluidic chip |
| Matrix stiffness and shear stresses modulate hepatocyte functions in a fibrotic liver sinusoidal model 期刊论文 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2020, 卷号: 320, 期号: 3, 页码: G272-G282 作者: Li W(李旺); Li PW(李培文); Li N(李宁); Du Y(杜宇); Lv SQ(吕守芹); Elad, David; Long M(龙勉) Adobe PDF(2812Kb)  |  收藏  |  浏览/下载:186/91  |  提交时间:2022/10/25 hepatocytes liver fibrosis matrix stiffness shear flow three-dimensional liver sinusoidal model |
| Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文 EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7 作者: Shu XY(舒芯钰); Li N(李宁); Huang DD(黄丹丹); Zhang Y(章燕); Lv SQ(吕守芹); Long M(龙勉) 浏览  |  Adobe PDF(1108Kb)  |  收藏  |  浏览/下载:451/168  |  提交时间:2020/04/07 beta(2) integrin Ligands Calcium transients Bond strength Mechanotransduction Shear stress |
| Flow-enhanced priming of hESCs through H2B acetylation and chromatin decondensation 期刊论文 STEM CELL RESEARCH & THERAPY, 2019, 卷号: 10, 期号: 1, 页码: 16 作者: Wang JW(王家文); Wu Y(武亿); Zhang X(张潇); Zhang F(张帆); Lv DY(吕东媛); Shang GB(上官冰); Gao YX(高宇欣); Long M(龙勉) 浏览  |  Adobe PDF(2406Kb)  |  收藏  |  浏览/下载:219/68  |  提交时间:2020/03/11 Embryonic stem cell Fluid shear mechanomics Nuclear spreading Histone acetylation Chromatin decondensation |
| Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文 CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279 作者: Li N(李宁); Zhang X(张潇); Li PW; Yang H; Tong CF; Lv SQ(吕守芹); Zhang Y(章燕); Ye ZY; Pan J; Long M(龙勉) 浏览  |  Adobe PDF(865Kb)  |  收藏  |  浏览/下载:395/192  |  提交时间:2018/10/30 Liver sinusoidal endothelial cells neutrophils beta(2) integrin shear flow mechanical strength |
| Neutrophil adhesion and crawling dynamics on liver sinusoidal endothelial cells under shear flow 期刊论文 EXPERIMENTAL CELL RESEARCH, 2017, 卷号: 351, 期号: 1, 页码: 91-99 作者: Yang H(杨浩); Li N(李宁); Du Y(杜宇); Tong CF(佟春芳); Lv SQ(吕守芹); Hu JR; Zhang Y(章燕); Long M(龙勉); Long, M (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100190, Peoples R China. 浏览  |  Adobe PDF(2025Kb)  |  收藏  |  浏览/下载:680/276  |  提交时间:2017/07/24 Neutrophils Liver Sinusoids Shear Flow Adhesive Molecules Kupffer Cells |
| Combined modeling of cell aggregation and adhesion mediated by receptor-ligand interactions under shear flow 期刊论文 Theoretical and Applied Mechanics Letters, 2015, 卷号: 5, 期号: 6, 页码: 216-221 作者: Du Y(杜宇); Peng S(彭爽); Cui Yuhong; Lv SQ(吕守芹); Zhang Y(章燕); Long M(龙勉) 浏览  |  Adobe PDF(961Kb)  |  收藏  |  浏览/下载:361/57  |  提交时间:2017/09/26 Cell Adhesion Aggregation Kinetics Shear Flow |