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Molecular dynamics simulation of shear- and stretch-induced dissociation of P-selectin/PSGL-1 complex 期刊论文
BIOPHYSICAL JOURNAL, 2012, 卷号: 102, 期号: 1, 页码: 112-120
作者:  Kang YY(康英永);  Lv SQ(吕守芹);  Ren P(任鹏);  Huo B(霍波);  Long M(龙勉);  Huo, B (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100080, Peoples R China.
Adobe PDF(1143Kb)  |  收藏  |  浏览/下载:960/197  |  提交时间:2013/01/18
Selectin Glycoprotein Ligand-1  Granule Membrane-protein  P-selectin  Cell-adhesion  Beta-switch  Endothelial-cells  Catch Bonds  Ib-alpha  Flow  Transition  
Determining beta(2)-Integrin and Intercellular Adhesion Molecule 1 Binding Kinetics in Tumor Cell Adhesion to Leukocytes and Endothelial Cells by a Gas-driven Micropipette Assay 期刊论文
Journal of Biological Chemistry, 2011, 卷号: 286, 期号: 40, 页码: 34777-34787
作者:  Fu ZL(傅长亮);  Tong CF(佟春芳);  Wang ML;  Gao YX(高宇欣);  Zhang Y(章燕);  Lv SQ(吕守芹);  Liang SL;  Dong C;  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100190, Peoples R China
Adobe PDF(1888Kb)  |  收藏  |  浏览/下载:1302/230  |  提交时间:2012/04/01
Mammary Adenocarcinoma Cells  Hydrodynamic Shear  Melanoma Adhesion  2-dimensional Kinetics  Human Neutrophils  P-selectin  Metastasis Development  Ligand Interactions  Concurrent Binding  Cancer Metastasis  
Probe stiffness regulates receptor-ligand bond lifetime under force 期刊论文
Science China-Physics Mechanics & Astronomy, 2011, 卷号: 54, 期号: 5, 页码: 923-929
作者:  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100190, Peoples R China
Adobe PDF(534Kb)  |  收藏  |  浏览/下载:1332/249  |  提交时间:2012/04/01
Probe Stiffness  Bond Lifetime  Optical Trap  Selectin Glycoprotein Ligand-1  P-selectin  Cell-adhesion  Binding-kinetics  Leukocytes  Molecule  Psgl-1  Flow  
Measuring Binding Kinetics Of Surface-Bound Molecules Using The Surface Plasmon Resonance Technique 期刊论文
Analytical Biochemistry, 2008, 页码: 195-201
作者:  Li BX(李宝霞);  Chen J(陈娟);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Natl Micrograv Lab, Beijing 100190, Peoples R China.
Adobe PDF(600Kb)  |  收藏  |  浏览/下载:1057/213  |  提交时间:2009/08/03
Cellular Off-rate  Cellular On-rate  Response Unit  Kinetic Model  Optical Biosensor Literature  Selectin  Antibody  Biacore  Antigen  Constants  Transport  Protein  Cells  Shear  
Low Spring Constant Regulates P-Selectin-Psgl-1 Bond Rupture 期刊论文
Biophysical Journal, 2008, 页码: 5439-5448
作者:  Zhang Y(章燕);  Sun GY(孙淦云);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Natl Micrograv Lab, Beijing 100190, Peoples R China.
Adobe PDF(634Kb)  |  收藏  |  浏览/下载:919/202  |  提交时间:2009/08/03
Selectin Glycoprotein Ligand-1  P-selectin  Cell-adhesion  Binding-kinetics  Force  Dissociation  Lifetime  Flow  Microscope  Leukocytes  
Two-Dimensional Kinetics Of Beta(2)-Integrin And Icam-1 Bindings Between Neutrophils And Melanoma Cells In A Shear Flow 期刊论文
American Journal of Physiology-Cell Physiology, 2008, 页码: C743-C753
作者:  Liang SL;  Fu ZL(傅长亮);  Wagner D;  Guo HG;  Zhan DY;  Dong C;  Long M(龙勉);  Dong, C (reprint author), Penn State Univ, Dept Bioengn, University Pk, PA 16802 USA.
Adobe PDF(727Kb)  |  收藏  |  浏览/下载:718/137  |  提交时间:2009/08/03
Heterotypic Cell Aggregation  Adhesion Molecule  Leukocyte  Tumor Cell  Reverse Rate  Binding Affinity  Probabilistic Model  Polymorpho-nuclear Neutrophils  Intercellular Adhesion Molecule-1  Intercellular-adhesion Molecule-1  Ligand-mediated Adhesion  Hydrodynamic Shear  L-selectin  Malignant-melanoma  Dynamic Regulation  Variant Isoforms  Stable Adhesion  Latex Spheres  P-selectin