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A Novel Human Antibody, HF, against HER2/erb-B2 Obtained by a Computer-Aided Antibody Design Method 期刊论文
ENGINEERING, 2021, 卷号: 7, 期号: 11, 页码: 1566-1576
Authors:  Qiao, Chunxia;  Lv, Ming;  Li, Xinying;  Lang, Xiaoling;  Lv SQ(吕守芹);  Long M(龙勉);  Li, Yan;  Geng, Shusheng;  Lin, Zhou;  Shen, Beifen;  Feng, Jiannan
Adobe PDF(4174Kb)  |  Favorite  |  View/Download：207/37  |  Submit date：2022/02/17
HER2/erb-B2  Human antibody  Computer-aided design  
Mapping the morphological identifiers of distinct conformations via the protein translocation current in nanopores 期刊论文
NANOSCALE, 2021, 卷号: 13, 期号: 12, 页码: 14
Authors:  Zhang MK(张明坤);  Chen SB(陈深宝);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Li LD(李林达);  Lv SQ(吕守芹);  Long M(龙勉)
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Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Wu Y(武亿);  Li W(李旺);  Zhang XY(张晓宇);  Li PW(李培文);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1359Kb)  |  Favorite  |  View/Download：399/112  |  Submit date：2021/05/06
Liver sinusoidal endothelial cell  Shear stress  Mechanical stretch  Extracellular matrix  Stiffness  
Multi-scale molecular dynamics simulations and applications on mechanosensitive proteins of integrins* 期刊论文
CHINESE PHYSICS B, 2021, 卷号: 30, 期号: 3, 页码: 8
Authors:  Lv SQ(吕守芹);  Ding QH(丁奇寒);  Zhang MK(张明坤);  Long M(龙勉)
Adobe PDF(834Kb)  |  Favorite  |  View/Download：288/88  |  Submit date：2021/04/19
molecular dynamics simulations  mechanosensitive protein  allosteric dynamics  integrin  
CD44-配体相互作用的生物力学与功能调控 期刊论文
力学学报, 2021, 卷号: 53, 期号: 02, 页码: 539-553
Authors:  李林达;  丁奇寒;  陈深宝;  吕守芹;  龙勉;  郭兴明
Adobe PDF(796Kb)  |  Favorite  |  View/Download：423/99  |  Submit date：2021/04/19
CD44  选择素  透明质酸  细胞粘附  力学调控  炎症反应  
Mechanically Regulated Outside-In Activation of an I-Domain-Containing Integrin 期刊论文
BIOPHYSICAL JOURNAL, 2020, 卷号: 119, 期号: 5, 页码: 966-977
Authors:  Mao DB(毛德斌);  Lv SQ(吕守芹);  Zhang X(张潇);  Long M(龙勉)
Adobe PDF(2480Kb)  |  Favorite  |  View/Download：256/69  |  Submit date：2020/10/29
Mechanomics analysis of hESCs under combined mechanical shear, stretch, and compression 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2020, 页码: 18
Authors:  Zhang F(张帆);  Wang JW(王家文);  Lv DY(吕东媛);  Zheng L(郑璐);  Shang GB(上官冰);  Gao YX(高宇欣);  Wu Y(武亿);  Long M(龙勉)
Adobe PDF(8050Kb)  |  Favorite  |  View/Download：326/175  |  Submit date：2020/10/23
Mechanomics  hESCs  iTRAQ  GSEA  WGCNA  
Mechanochemical modeling of neutrophil migration based on four signaling layers, integrin dynamics, and substrate stiffness 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2018, 卷号: 17, 期号: 6, 页码: 1611-1630
Authors:  Feng SL(冯世亮);  Zhou LW(周吕文);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(3483Kb)  |  Favorite  |  View/Download：421/146  |  Submit date：2019/05/30
Chemotaxis  Cytoskeletal remodeling  Mathematical model  Biochemical  Biomechanical  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
Authors:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
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Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Mechanokinetics of receptor-ligand interactions in cell adhesion 期刊论文
Acta Mechanica Sinica, 2015, 卷号: 31, 期号: 2, 页码: 248-258
Authors:  Li N(李宁);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Ctr Biomech & Bioengn, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100190, Peoples R China.
Adobe PDF(809Kb)  |  Favorite  |  View/Download：555/169  |  Submit date：2015/07/21
Receptor-ligand Interactions  Selectins  Beta(2) Integrins  2d Binding Kinetics