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中国科学院力学研究所机构知识库
Knowledge Management System of Institue of Mechanics, CAS
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微重力重点实验室 [11]
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吕守芹 [12]
龙勉 [12]
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Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli
期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
Authors:
Shu XY(舒芯钰)
;
Li N(李宁)
;
Wu Y(武亿)
;
Li W(李旺)
;
Zhang XY(张晓宇)
;
Li PW(李培文)
;
Lv DY(吕东媛)
;
Lv SQ(吕守芹)
;
Long M(龙勉)
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Submit date:2021/05/06
Liver sinusoidal endothelial cell
Shear stress
Mechanical stretch
Extracellular matrix
Stiffness
Multi-scale molecular dynamics simulations and applications on mechanosensitive proteins of integrins*
期刊论文
CHINESE PHYSICS B, 2021, 卷号: 30, 期号: 3, 页码: 8
Authors:
Lv SQ(吕守芹)
;
Ding QH(丁奇寒)
;
Zhang MK(张明坤)
;
Long M(龙勉)
Adobe PDF(834Kb)
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Submit date:2021/04/19
molecular dynamics simulations
mechanosensitive protein
allosteric dynamics
integrin
Mechanically Regulated Outside-In Activation of an I-Domain-Containing Integrin
期刊论文
BIOPHYSICAL JOURNAL, 2020, 卷号: 119, 期号: 5, 页码: 966-977
Authors:
Mao DB(毛德斌)
;
Lv SQ(吕守芹)
;
Zhang X(张潇)
;
Long M(龙勉)
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Submit date:2020/10/29
Salt bridge interactions within the beta(2) integrin alpha(7) helix mediate force-induced binding and shear resistance ability
期刊论文
FEBS JOURNAL, 2018, 卷号: 285, 期号: 2, 页码: 261-274
Authors:
Zhang X(张潇)
;
Li LD
;
Li N(李宁)
;
Shu XY
;
Zhou LW(周吕文)
;
Lv SQ(吕守芹)
;
Chen SB
;
Mao DB
;
Long M(龙勉)
Adobe PDF(2053Kb)
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Submit date:2018/10/30
beta(2) integrin
allostery
conformational stability
force
salt bridge interaction
Dynamic contributions of P- and E-selectins to beta(2)-integrin-induced neutrophil transmigration
期刊论文
FASEB JOURNAL, 2017, 卷号: 31, 期号: 1, 页码: 212-+
Authors:
Gong YX
;
Zhang Y(章燕)
;
Feng SL
;
Liu XF
;
Lv SQ(吕守芹)
;
Long M(龙勉)
;
Long, M (reprint author), Chinese Acad Sci, Ctr Biomech & Bioengn, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
;
Long, M (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Natl Micrograv Lab, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
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Submit date:2017/04/26
Identification of the Conformational transition pathway in PIP2 Opening Kir Channels
期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5, 页码: 11289
Authors:
Li JW
;
Lv SQ(吕守芹)
;
Liu YZ
;
Pang CL
;
Chen YF
;
Zhang SH
;
Yu H
;
Long M(龙勉)
;
Zhang HL
;
Logothetis DE
;
Zhan Y
;
An HL
;
An, HL (reprint author), Hebei Univ Technol, Inst Biophys, Sch Sci, Key Lab Mol Biophys, Tianjin 300401, Hebei Province, Peoples R China.
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Submit date:2015/07/21
Mechanokinetics of receptor-ligand interactions in cell adhesion
期刊论文
Acta Mechanica Sinica, 2015, 卷号: 31, 期号: 2, 页码: 248-258
Authors:
Li N(李宁)
;
Lv SQ(吕守芹)
;
Zhang Y(章燕)
;
Long M(龙勉)
;
Long, M (reprint author), Chinese Acad Sci, Ctr Biomech & Bioengn, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100190, Peoples R China.
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Submit date:2015/07/21
Receptor-ligand Interactions
Selectins
Beta(2) Integrins
2d Binding Kinetics
Distinct binding affinities of Mac-1 and LFA-1 in neutrophil activation
期刊论文
JOURNAL OF IMMUNOLOGY, 2013, 卷号: 190, 期号: 8, 页码: 4371-4381
Authors:
Li N(李宁)
;
Mao DB(毛德斌)
;
Lv SQ(吕守芹)
;
Tong CF(佟春芳)
;
Zhang Y(章燕)
;
Long M(龙勉)
;
Long, M (reprint author), Chinese Acad Sci, Inst Mech, Natl Micrograv Lab, Key Lab Micrograv, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
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Submit date:2013/05/21
The cytosolic GH loop regulates the phosphatidylinositol 4,5-bisphosphate-induced gating kinetics of Kir2 channels
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 卷号: 287, 期号: 50, 页码: 42278-42287
Authors:
An HL
;
Lv SQ(吕守芹)
;
Li JW
;
Meng XY
;
Zhan Y
;
Cui M
;
Long M(龙勉)
;
Zhang HL
;
Logothetis DE
;
Long, M
;
Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100190, Peoples R China.
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Submit date:2013/01/18
Rectifier K++ Channels
Beta-gamma-subunits
Potassium Channels
Crystal-structure
G-proteins
Structural Basis
Voltage-sensor
Pip2
Activation
Dynamics
Conformational Stability Analyses of Alpha Subunit I Domain of LFA-1 and Mac-1
期刊论文
PLOS One, 2011, 卷号: 6, 期号: 8, 页码: e24188
Authors:
Mao DB(毛德斌)
;
Lv SQ(吕守芹)
;
Li N(李宁)
;
Zhang Y(章燕)
;
Long M(龙勉)
;
Mao, DB (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100080, Peoples R China
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Submit date:2012/04/01
A-domain
Molecular-dynamics
Structural Basis
Integrin Activation
Crystal-structure
Cell-adhesion
T-cell
Neutrophils
Affinity
Migration