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中国科学院力学研究所机构知识库
Knowledge Management System of Institue of Mechanics, CAS
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微重力重点实验室 [10]
Creator
吕守芹 [10]
李宁 [10]
章燕 [10]
龙勉 [10]
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Wang ML [2]
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Creator:李宁
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Author:章燕
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Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands
期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
Authors:
Shu XY(舒芯钰)
;
Li N(李宁)
;
Huang DD(黄丹丹)
;
Zhang Y(章燕)
;
Lv SQ(吕守芹)
;
Long M(龙勉)
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Submit date:2020/04/07
beta(2) integrin
Ligands
Calcium transients
Bond strength
Mechanotransduction
Shear stress
Binding of intercellular adhesion molecule 1 to beta(2)-integrin regulates distinct cell adhesion processes on hepatic and cerebral endothelium
期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2018, 卷号: 315, 期号: 3, 页码: C409-C421
Authors:
Tong CF(佟春芳)
;
Zhang Y(章燕)
;
Lv SQ(吕守芹)
;
Li N(李宁)
;
Gong YX(龚一心)
;
Yang H
;
Feng SL
;
Du Y
;
Huang DD
;
Long M(龙勉)
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Adobe PDF(1593Kb)
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  |  
Submit date:2018/10/30
brain
ICAM-1
integrin
kinetics
liver
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations
期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
Authors:
Li N(李宁)
;
Zhang X(张潇)
;
Li PW
;
Yang H
;
Tong CF
;
Lv SQ(吕守芹)
;
Zhang Y(章燕)
;
Ye ZY
;
Pan J
;
Long M(龙勉)
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Submit date:2018/10/30
Liver sinusoidal endothelial cells
neutrophils
beta(2) integrin
shear flow
mechanical strength
Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling
期刊论文
MOLECULAR BIOLOGY OF THE CELL, 2018, 卷号: 29, 期号: 4, 页码: 408-418
Authors:
Li N(李宁)
;
Yang H(杨浩)
;
Wang ML
;
Lv SQ(吕守芹)
;
Zhang Y(章燕)
;
Long M(龙勉)
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Submit date:2018/10/30
Mechanokinetics of receptor-ligand interactions in cell adhesion
期刊论文
Acta Mechanica Sinica, 2015, 卷号: 31, 期号: 2, 页码: 248-258
Authors:
Li N(李宁)
;
Lv SQ(吕守芹)
;
Zhang Y(章燕)
;
Long M(龙勉)
;
Long, M (reprint author), Chinese Acad Sci, Ctr Biomech & Bioengn, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100190, Peoples R China.
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Submit date:2015/07/21
Receptor-ligand Interactions
Selectins
Beta(2) Integrins
2d Binding Kinetics
The impact of N-terminal phosphorylation on LHCII conformation in state transition
期刊论文
Acta Mechanica Sinica, 2014, 卷号: 30, 期号: 3, 页码: 447-456
Authors:
Ding JH(丁锦鸿)
;
Li N(李宁)
;
Wang ML
;
Zhang Y(章燕)
;
Lv SQ(吕守芹)
;
Long M(龙勉)
;
Lu, SQ (reprint author), Chinese Acad Sci, Natl Micrograv Lab, Key Lab Micrograv, Beijing 100190, Peoples R China.
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Submit date:2014/09/03
State Transition
Lhcii
Phosphorylation
Conformation
Distinct binding affinities of Mac-1 and LFA-1 in neutrophil activation
期刊论文
JOURNAL OF IMMUNOLOGY, 2013, 卷号: 190, 期号: 8, 页码: 4371-4381
Authors:
Li N(李宁)
;
Mao DB(毛德斌)
;
Lv SQ(吕守芹)
;
Tong CF(佟春芳)
;
Zhang Y(章燕)
;
Long M(龙勉)
;
Long, M (reprint author), Chinese Acad Sci, Inst Mech, Natl Micrograv Lab, Key Lab Micrograv, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
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Submit date:2013/05/21
Conformational Stability Analyses of Alpha Subunit I Domain of LFA-1 and Mac-1
期刊论文
PLOS One, 2011, 卷号: 6, 期号: 8, 页码: e24188
Authors:
Mao DB(毛德斌)
;
Lv SQ(吕守芹)
;
Li N(李宁)
;
Zhang Y(章燕)
;
Long M(龙勉)
;
Mao, DB (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100080, Peoples R China
Adobe PDF(818Kb)
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Submit date:2012/04/01
A-domain
Molecular-dynamics
Structural Basis
Integrin Activation
Crystal-structure
Cell-adhesion
T-cell
Neutrophils
Affinity
Migration
加载历史对低刚度下P-选择素-PSGL-1键寿命的影响
期刊论文
医用生物力学, 2009, 卷号: 24, 期号: 增刊1, 页码: 26-27
Authors:
章燕
;
孙淦云
;
吕守芹
;
李宁
;
龙勉
Adobe PDF(126Kb)
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Submit date:2010/05/03
加载历史:5107
选择素:5028
低刚度:4013
寿命:3064
加载率:2582
配体分子:2236
蛋白质间相互作用:2231
受体:1907
调控因素:1243
炎症反应:1139
Force spectroscopy of single receptor-ligand bond using an optical trap
会议论文
2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009, Shanghai, China, November 2, 2009 - November 6, 2009
Authors:
Zhang Y(章燕)
;
Sun GY(孙淦云)
;
Li N(李宁)
;
Huo B(霍波)
;
Lv SQ(吕守芹)
;
Long M(龙勉)
;
Zhang, Y.
Adobe PDF(2190Kb)
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Submit date:2017/07/14
Bond Dissociation
Force Spectroscopy
Low Loading
Novel Methods
Optical Trap
Receptor-ligand Bonds
Receptor-ligand Interactions
Thermal Fluctuations
Unbinding Transitions