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FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17
Authors:  Zhang XY(张晓宇);  Li PW(李培文);  Zhou J(周瑾);  Zhang ZL(张子良);  Wu H(吴欢);  Shu XY(舒芯钰);  Li W(李旺);  Wu Y(武亿);  Du Y(杜宇);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Favorite  |  View/Download:24/0  |  Submit date:2024/04/02
Liver sinusoidal endothelial cells  Fenestrae  Liver fibrosis  Cytoskeleton remodeling  FAK  MAPK  
Direct mechanical exposure initiates hepatocyte proliferation 期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
Authors:  Li, Wang;  Wu Y(武亿);  Hu, Wenhui;  Zhou J(周瑾);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang, Ziliang;  Wu, Huan;  Du, Yu;  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Adobe PDF(3334Kb)  |  Favorite  |  View/Download:59/0  |  Submit date:2024/01/02
Mechanotransduction  FAK  hepatic sinusoid chip  
Binding of different hyaluronan to CD44 mediates distinct cell adhesion dynamics under shear flow 期刊论文
FEBS JOURNAL, 2023
Authors:  Li LD(李林达);  Ding QH(丁奇寒);  Wu Y(武亿);  Zheng Z(郑植);  Zhang XN(张晓宁);  Zhang MK(张明焜);  Long M(龙勉);  Lv SQ(吕守芹)
Adobe PDF(6108Kb)  |  Favorite  |  View/Download:63/1  |  Submit date:2023/07/17
CD44  HA  molecular weight  shear flow  two-dimensional interaction  
Theoretical modeling of trail formation of a migrating neutrophil on substrate 期刊论文
ACTA MECHANICA SINICA, 2023, 卷号: 39, 期号: 6, 页码: 622461
Authors:  Zhang XN(张晓宁);  Hu WH(胡文慧);  Gao WB(高文博);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(2299Kb)  |  Favorite  |  View/Download:97/4  |  Submit date:2023/07/17
Neutrophil migration  Trail formation  Theoretical modeling  Numerical calculation  Parametric analysis  
Biomechanics in liver regeneration after partial hepatectomy 期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2023, 卷号: 11, 页码: 1165651
Authors:  Wu Y(武亿);  Li N(李宁);  Shu XY(舒芯钰);  Li W(李旺);  Zhang XY(张晓宇);  Lv DY(吕东媛);  Long M(龙勉)
Adobe PDF(2065Kb)  |  Favorite  |  View/Download:71/0  |  Submit date:2023/07/17
liver regeneration  partial hepatectomy  hemodynamics  mechanical loading  mechanotransduction  
Potential Roles of YAP/TAZ Mechanotransduction in Spaceflight-Induced Liver Dysfunction 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 3, 页码: 20
Authors:  Li W(李旺);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang ZL(张子良);  Sun SJ(孙树津);  Li N(李宁);  Long M(龙勉)
Adobe PDF(1498Kb)  |  Favorite  |  View/Download:128/2  |  Submit date:2023/03/20
microgravity  liver metabolism  mechanosensing  cytoskeleton  nuclear deformation  phase separation  
Characterizing liver sinusoidal endothelial cell fenestrae on soft substrates upon AFM imaging and deep learning 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2020, 卷号: 1864, 期号: 12, 页码: 9
Authors:  Li PW(李培文);  Zhou J(周瑾);  Li W(李旺);  Wu H(吴欢);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Lv SQ(吕守芹);  Pan J;  Zhang CY;  Li N(李宁);  Long M(龙勉)
Adobe PDF(4976Kb)  |  Favorite  |  View/Download:683/386  |  Submit date:2020/11/30
Liver sinusoidal endothelial cells  Fenestrae  Atomic force microscopy  Imaging recognition  Fully convolutional networks  Substrate stiffness  
Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1108Kb)  |  Favorite  |  View/Download:479/178  |  Submit date:2020/04/07
beta(2) integrin  Ligands  Calcium transients  Bond strength  Mechanotransduction  Shear stress  
Microgravity-induced hepatogenic differentiation of rBMSCs on board the SJ-10 satellite 期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 3, 页码: 4273-4286
Authors:  Lv DY(吕东媛);  Sun SJ(孙树津);  Zhang F(张帆);  Luo CH(罗春花);  Zheng L;  Wu Y(武毅);  Li N(李宁);  Zhang C;  Wang CZ;  Chen Q;  Long M(龙勉)
Adobe PDF(3477Kb)  |  Favorite  |  View/Download:317/100  |  Submit date:2019/04/11
mesenchymal stem cells  mechanotransduction  hepatocyte  signaling pathway  
Binding of intercellular adhesion molecule 1 to beta(2)-integrin regulates distinct cell adhesion processes on hepatic and cerebral endothelium 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2018, 卷号: 315, 期号: 3, 页码: C409-C421
Authors:  Tong CF(佟春芳);  Zhang Y(章燕);  Lv SQ(吕守芹);  Li N(李宁);  Gong YX(龚一心);  Yang H;  Feng SL;  Du Y;  Huang DD;  Long M(龙勉)
Adobe PDF(1593Kb)  |  Favorite  |  View/Download:571/276  |  Submit date:2018/10/30
brain  ICAM-1  integrin  kinetics  liver