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Two Complementary Signaling Pathways Depict Eukaryotic Chemotaxis: A Mechanochemical Coupling Model 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9, 页码: 12
Authors:  Zhou LW(周吕文);  Feng SL(冯世亮);  Li L(李龙);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
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chemotaxis  cytoskeletal remodeling  mathematical model  biochemical  biomechanical  
E-selectin negatively regulates polymorphonuclear neutrophil transmigration through altered endothelial junction integrity 期刊论文
FASEB JOURNAL, 2021, 卷号: 35, 期号: 5, 页码: 15
Authors:  Huang DD(黄丹丹);  Ding QH(丁奇寒);  Chen SB(陈深宝);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
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cytoskeletal remodeling  endothelial integrity  E-selectin  neutrophil  transmigration  
Mechanochemical modeling of neutrophil migration based on four signaling layers, integrin dynamics, and substrate stiffness 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2018, 卷号: 17, 期号: 6, 页码: 1611-1630
Authors:  Feng SL(冯世亮);  Zhou LW(周吕文);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(3483Kb)  |  Favorite  |  View/Download:412/142  |  Submit date:2019/05/30
Chemotaxis  Cytoskeletal remodeling  Mathematical model  Biochemical  Biomechanical  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
Authors:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
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Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling 期刊论文
MOLECULAR BIOLOGY OF THE CELL, 2018, 卷号: 29, 期号: 4, 页码: 408-418
Authors:  Li N(李宁);  Yang H(杨浩);  Wang ML;  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
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Neutrophil adhesion and crawling dynamics on liver sinusoidal endothelial cells under shear flow 期刊论文
EXPERIMENTAL CELL RESEARCH, 2017, 卷号: 351, 期号: 1, 页码: 91-99
Authors:  Yang H(杨浩);  Li N(李宁);  Du Y(杜宇);  Tong CF(佟春芳);  Lv SQ(吕守芹);  Hu JR;  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100190, Peoples R China.
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Neutrophils  Liver Sinusoids  Shear Flow  Adhesive Molecules  Kupffer Cells  
Dynamic contributions of P- and E-selectins to beta(2)-integrin-induced neutrophil transmigration 期刊论文
FASEB JOURNAL, 2017, 卷号: 31, 期号: 1, 页码: 212-+
Authors:  Gong YX;  Zhang Y(章燕);  Feng SL;  Liu XF;  Lv SQ(吕守芹);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Ctr Biomech & Bioengn, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.;  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Natl Micrograv Lab, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
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Mechanokinetics of receptor-ligand interactions in cell adhesion 期刊论文
Acta Mechanica Sinica, 2015, 卷号: 31, 期号: 2, 页码: 248-258
Authors:  Li N(李宁);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Ctr Biomech & Bioengn, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100190, Peoples R China.
View  |  Adobe PDF(809Kb)  |  Favorite  |  View/Download:541/165  |  Submit date:2015/07/21
Receptor-ligand Interactions  Selectins  Beta(2) Integrins  2d Binding Kinetics  
Distinct binding affinities of Mac-1 and LFA-1 in neutrophil activation 期刊论文
JOURNAL OF IMMUNOLOGY, 2013, 卷号: 190, 期号: 8, 页码: 4371-4381
Authors:  Li N(李宁);  Mao DB(毛德斌);  Lv SQ(吕守芹);  Tong CF(佟春芳);  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Natl Micrograv Lab, Key Lab Micrograv, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
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Tyrosine replacement of PSGL-1 reduces association kinetics with P- and L-selectin on the cell membrane 期刊论文
BIOPHYSICAL JOURNAL, 2012, 卷号: 103, 期号: 4, 页码: 777-785
Authors:  Xiao BT(肖波涛);  Tong CF(佟春芳);  Jia XL(贾潇凌);  Guo R(郭瑞);  Lv SQ(吕守芹);  Zhang Y(章燕);  McEver RP;  Zhu C;  Long M(龙勉);  Long, MA;  Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100080, Peoples R China.
Adobe PDF(775Kb)  |  Favorite  |  View/Download:1035/272  |  Submit date:2013/01/18
Ligand Binding-kinetics  Glycoprotein Ligand-1  Molecular-dynamics  Adhesion  Sulfation  Proteins  Glycosulfopeptides  Identification  Dissociation  Recognition