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Mechanochemical modeling of neutrophil migration based on four signaling layers, integrin dynamics, and substrate stiffness 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2018, 卷号: 17, 期号: 6, 页码: 1611-1630
Authors:  Feng SL(冯世亮);  Zhou LW(周吕文);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(3483Kb)  |  Favorite  |  View/Download：412/142  |  Submit date：2019/05/30
Chemotaxis  Cytoskeletal remodeling  Mathematical model  Biochemical  Biomechanical  
Dynamic seesaw model for rapid signaling responses in eukaryotic chemotaxis 期刊论文
PHYSICAL BIOLOGY, 2018, 卷号: 15, 期号: 5
Authors:  Feng SL;  Zhou LW(周吕文);  Lv SQ(吕守芹);  Zhang Y(章燕)
View  |  Adobe PDF(1669Kb)  |  Favorite  |  View/Download：331/81  |  Submit date：2018/07/17
Polarization  Signaling Cascade  Mathematical Model  Lattice-boltzmann Method  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
Authors:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
View  |  Adobe PDF(865Kb)  |  Favorite  |  View/Download：406/194  |  Submit date：2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Theoretical modeling of mechanical homeostasis of a mammalian cell under gravity-directed vector 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2018, 卷号: 17, 期号: 1, 页码: 191-203
Authors:  Zhou LW(周吕文);  Zhang C(张晨);  Zhang F(张芳);  Lv SQ(吕守芹);  Sun SJ(孙树津);  Lv DY(吕东媛);  Long M(龙勉)
View  |  Adobe PDF(860Kb)  |  Favorite  |  View/Download：413/223  |  Submit date：2018/10/30
Gravity directed  Mechanosensing  Nucleus translocation  Cytoskeletal remodeling  FAC reorganization  
Salt bridge interactions within the beta(2) integrin alpha(7) helix mediate force-induced binding and shear resistance ability 期刊论文
FEBS JOURNAL, 2018, 卷号: 285, 期号: 2, 页码: 261-274
Authors:  Zhang X(张潇);  Li LD;  Li N(李宁);  Shu XY;  Zhou LW(周吕文);  Lv SQ(吕守芹);  Chen SB;  Mao DB;  Long M(龙勉)
View  |  Adobe PDF(2053Kb)  |  Favorite  |  View/Download：249/67  |  Submit date：2018/10/30
beta(2) integrin  allostery  conformational stability  force  salt bridge interaction