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A Novel Human Antibody, HF, against HER2/erb-B2 Obtained by a Computer-Aided Antibody Design Method 期刊论文
ENGINEERING, 2021, 卷号: 7, 期号: 11, 页码: 1566-1576
Authors:  Qiao, Chunxia;  Lv, Ming;  Li, Xinying;  Lang, Xiaoling;  Lv SQ(吕守芹);  Long M(龙勉);  Li, Yan;  Geng, Shusheng;  Lin, Zhou;  Shen, Beifen;  Feng, Jiannan
Adobe PDF(4174Kb)  |  Favorite  |  View/Download:203/35  |  Submit date:2022/02/17
HER2/erb-B2  Human antibody  Computer-aided design  
Mechanically Regulated Outside-In Activation of an I-Domain-Containing Integrin 期刊论文
BIOPHYSICAL JOURNAL, 2020, 卷号: 119, 期号: 5, 页码: 966-977
Authors:  Mao DB(毛德斌);  Lv SQ(吕守芹);  Zhang X(张潇);  Long M(龙勉)
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Salt bridge interactions within the beta(2) integrin alpha(7) helix mediate force-induced binding and shear resistance ability 期刊论文
FEBS JOURNAL, 2018, 卷号: 285, 期号: 2, 页码: 261-274
Authors:  Zhang X(张潇);  Li LD;  Li N(李宁);  Shu XY;  Zhou LW(周吕文);  Lv SQ(吕守芹);  Chen SB;  Mao DB;  Long M(龙勉)
View  |  Adobe PDF(2053Kb)  |  Favorite  |  View/Download:258/71  |  Submit date:2018/10/30
beta(2) integrin  allostery  conformational stability  force  salt bridge interaction  
The impact of N-terminal phosphorylation on LHCII conformation in state transition 期刊论文
Acta Mechanica Sinica, 2014, 卷号: 30, 期号: 3, 页码: 447-456
Authors:  Ding JH(丁锦鸿);  Li N(李宁);  Wang ML;  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉);  Lu, SQ (reprint author), Chinese Acad Sci, Natl Micrograv Lab, Key Lab Micrograv, Beijing 100190, Peoples R China.
View  |  Adobe PDF(746Kb)  |  Favorite  |  View/Download:702/149  |  Submit date:2014/09/03
State Transition  Lhcii  Phosphorylation  Conformation  
Distinct binding affinities of Mac-1 and LFA-1 in neutrophil activation 期刊论文
JOURNAL OF IMMUNOLOGY, 2013, 卷号: 190, 期号: 8, 页码: 4371-4381
Authors:  Li N(李宁);  Mao DB(毛德斌);  Lv SQ(吕守芹);  Tong CF(佟春芳);  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Natl Micrograv Lab, Key Lab Micrograv, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
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Tyrosine replacement of PSGL-1 reduces association kinetics with P- and L-selectin on the cell membrane 期刊论文
BIOPHYSICAL JOURNAL, 2012, 卷号: 103, 期号: 4, 页码: 777-785
Authors:  Xiao BT(肖波涛);  Tong CF(佟春芳);  Jia XL(贾潇凌);  Guo R(郭瑞);  Lv SQ(吕守芹);  Zhang Y(章燕);  McEver RP;  Zhu C;  Long M(龙勉);  Long, MA;  Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100080, Peoples R China.
Adobe PDF(775Kb)  |  Favorite  |  View/Download:1039/275  |  Submit date:2013/01/18
Ligand Binding-kinetics  Glycoprotein Ligand-1  Molecular-dynamics  Adhesion  Sulfation  Proteins  Glycosulfopeptides  Identification  Dissociation  Recognition  
Conformational Stability Analyses of Alpha Subunit I Domain of LFA-1 and Mac-1 期刊论文
PLOS One, 2011, 卷号: 6, 期号: 8, 页码: e24188
Authors:  Mao DB(毛德斌);  Lv SQ(吕守芹);  Li N(李宁);  Zhang Y(章燕);  Long M(龙勉);  Mao, DB (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100080, Peoples R China
Adobe PDF(818Kb)  |  Favorite  |  View/Download:1290/293  |  Submit date:2012/04/01
A-domain  Molecular-dynamics  Structural Basis  Integrin Activation  Crystal-structure  Cell-adhesion  T-cell  Neutrophils  Affinity  Migration  
Visualization of Allostery in P-Selectin Lectin Domain Using Md Simulations 期刊论文
PLOS ONE, 2010, 卷号: 5, 期号: 12, 页码: -
Authors:  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉);  Lu, SQ (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100080, Peoples R China.
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P-选择素/PSGL-1分子反应动力学和力作用下键解离的实验和分子动力学模拟 学位论文
博士论文,北京: 中国科学院研究生院, 2006
Authors:  吕守芹
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Forced Dissociation of Selectin-ligand Complexes Using Steered Molecular Dynamics Simulation 期刊论文
MCB, 2005, 卷号: 2, 期号: 4, 页码: 161-177
Authors:  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(620Kb)  |  Favorite  |  View/Download:738/172  |  Submit date:2007/06/15