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| FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17
作者: Zhang XY(张晓宇); Li PW(李培文); Zhou J(周瑾); Zhang ZL(张子良); Wu H(吴欢); Shu XY(舒芯钰); Li W(李旺) ; Wu Y(武亿); Du Y(杜宇); Lv DY(吕东媛); Lv SQ(吕守芹); Li N(李宁); Long M(龙勉)
  收藏 | 浏览/下载：8/0 | 提交时间：2024/04/02
Liver sinusoidal endothelial cells Fenestrae Liver fibrosis Cytoskeleton remodeling FAK MAPK |
| 剪切应力及基质硬度调控肝细胞功能的生物力学机制 学位论文
博士论文，北京: 中国科学院大学, 2023
作者: 李旺
Adobe PDF(8757Kb) | 收藏 | 浏览/下载：245/6 | 提交时间：2023/06/26
剪切应力 基质硬度 增殖 肝细胞特异性功能 力学转导 |
| Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer 期刊论文
ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448
作者: Li N(李宁); Zhang XY(张晓宇); Zhou J(周瑾); Li W(李旺); Shu XY(舒芯钰); Wu Y(武亿); Long M(龙勉)
 Adobe PDF(2553Kb) | 收藏 | 浏览/下载：323/90 | 提交时间：2022/10/23
Liver tissue stiffness Shear stress Hydrostatic pressure Hepatocytes Hepatocellular carcinoma Liver sinusoidal endothelial cells Hepatic stellate cells Mechanotransduction pathways Mechanomedicine Drug design and delivery |
| 力学微环境调控肝血窦内皮细胞表型维持与去分化 期刊论文
医用生物力学, 2021, 卷号: 36, 期号: S1, 页码: 302
作者: 李宁; 李珮文; 张晓宇; 舒芯钰; 李旺; 吕守芹; 龙勉
Adobe PDF(2274Kb) | 收藏 | 浏览/下载：191/32 | 提交时间：2022/03/16
肝血窦内皮细胞 去分化 微环境 |
| Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
作者: Shu XY(舒芯钰); Li N(李宁); Wu Y(武亿); Li W(李旺); Zhang XY(张晓宇); Li PW(李培文); Lv DY(吕东媛); Lv SQ(吕守芹); Long M(龙勉)
Adobe PDF(1359Kb) | 收藏 | 浏览/下载：368/101 | 提交时间：2021/05/06
Liver sinusoidal endothelial cell Shear stress Mechanical stretch Extracellular matrix Stiffness |
| Characterizing liver sinusoidal endothelial cell fenestrae on soft substrates upon AFM imaging and deep learning 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2020, 卷号: 1864, 期号: 12, 页码: 9
作者: Li PW(李培文); Zhou J(周瑾); Li W(李旺); Wu H(吴欢); Hu JR(胡锦荣); Ding QH(丁奇寒); Lv SQ(吕守芹); Pan J; Zhang CY; Li N(李宁); Long M(龙勉)
Adobe PDF(4976Kb) | 收藏 | 浏览/下载：649/375 | 提交时间：2020/11/30
Liver sinusoidal endothelial cells Fenestrae Atomic force microscopy Imaging recognition Fully convolutional networks Substrate stiffness |
| Matrix stiffness and shear stresses modulate hepatocyte functions in a fibrotic liver sinusoidal model 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2020, 卷号: 320, 期号: 3, 页码: G272-G282
作者: Li W(李旺); Li PW(李培文); Li N(李宁); Du Y(杜宇); Lv SQ(吕守芹); Elad, David; Long M(龙勉)
Adobe PDF(2812Kb) | 收藏 | 浏览/下载：176/86 | 提交时间：2022/10/25
hepatocytes liver fibrosis matrix stiffness shear flow three-dimensional liver sinusoidal model |
