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细胞黏附的力学建模及其力敏感性的机理研究 学位论文
博士论文,北京: 中国科学院研究生院, 2009
作者:  孔冬
Adobe PDF(4626Kb)  |  收藏  |  浏览/下载:850/3  |  提交时间:2009/04/13
细胞力学  细胞黏附  黏附斑  力敏感性  细胞重排  Cell Mechanics  Cell Adhesion  Focal Adhesion  Mechanosensitivity  Cell Reorientation  
采用热涨落方法直接测量受体-配体二维正反应率 学位论文
博士论文,北京: 中国科学院研究生院, 2008
作者:  孙淦云
Adobe PDF(4504Kb)  |  收藏  |  浏览/下载:505/0  |  提交时间:2009/04/13
L-Selectin Shedding Regulates Two-Dimensional Binding To Psgl-1 期刊论文
Biorheology, 2008, 卷号: 45, 页码: 74-75
作者:  Long M(龙勉);  Jia X
Adobe PDF(48Kb)  |  收藏  |  浏览/下载:754/113  |  提交时间:2009/08/03
Measuring Binding Kinetics Of Surface-Bound Molecules Using The Surface Plasmon Resonance Technique 期刊论文
Analytical Biochemistry, 2008, 页码: 195-201
作者:  Li BX(李宝霞);  Chen J(陈娟);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Natl Micrograv Lab, Beijing 100190, Peoples R China.
Adobe PDF(600Kb)  |  收藏  |  浏览/下载:1058/213  |  提交时间:2009/08/03
Cellular Off-rate  Cellular On-rate  Response Unit  Kinetic Model  Optical Biosensor Literature  Selectin  Antibody  Biacore  Antigen  Constants  Transport  Protein  Cells  Shear  
Low Spring Constant Regulates P-Selectin-Psgl-1 Bond Rupture 期刊论文
Biophysical Journal, 2008, 页码: 5439-5448
作者:  Zhang Y(章燕);  Sun GY(孙淦云);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Natl Micrograv Lab, Beijing 100190, Peoples R China.
Adobe PDF(634Kb)  |  收藏  |  浏览/下载:923/203  |  提交时间:2009/08/03
Selectin Glycoprotein Ligand-1  P-selectin  Cell-adhesion  Binding-kinetics  Force  Dissociation  Lifetime  Flow  Microscope  Leukocytes  
Two-Dimensional Kinetics Of Beta(2)-Integrin And Icam-1 Bindings Between Neutrophils And Melanoma Cells In A Shear Flow 期刊论文
American Journal of Physiology-Cell Physiology, 2008, 页码: C743-C753
作者:  Liang SL;  Fu ZL(傅长亮);  Wagner D;  Guo HG;  Zhan DY;  Dong C;  Long M(龙勉);  Dong, C (reprint author), Penn State Univ, Dept Bioengn, University Pk, PA 16802 USA.
Adobe PDF(727Kb)  |  收藏  |  浏览/下载:720/137  |  提交时间:2009/08/03
Heterotypic Cell Aggregation  Adhesion Molecule  Leukocyte  Tumor Cell  Reverse Rate  Binding Affinity  Probabilistic Model  Polymorpho-nuclear Neutrophils  Intercellular Adhesion Molecule-1  Intercellular-adhesion Molecule-1  Ligand-mediated Adhesion  Hydrodynamic Shear  L-selectin  Malignant-melanoma  Dynamic Regulation  Variant Isoforms  Stable Adhesion  Latex Spheres  P-selectin  
Impact of carrier stiffness and microtopology on two-dimensional kinetics of P-selectin and P-selectin glycoprotein ligand-1 (PSGL-1) interactions 期刊论文
Journal of Biological Chemistry, 2007, 卷号: 282, 期号: 13, 页码: 9846-9854
作者:  Wu L;  Xiao BT;  Jia XL(贾潇凌);  Zhang Y(章燕);  Lv SQ(吕守芹);  Chen J(陈娟);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Natl Micrograv Lab, Beijing 100080, Peoples R China.
Adobe PDF(457Kb)  |  收藏  |  浏览/下载:1067/178  |  提交时间:2009/08/03
Human Neutrophils  Binding-kinetics  Adhesion  Affinity  Rates  Flow  
P-选择素/PSGL-1分子反应动力学和力作用下键解离的实验和分子动力学模拟 学位论文
博士论文,北京: 中国科学院研究生院, 2006
作者:  吕守芹
Adobe PDF(3977Kb)  |  收藏  |  浏览/下载:958/1  |  提交时间:2009/04/13
Quantifying the Effects of Contact Duration, Loading Rate, and Approach Velocity on P-Selectin-PSGL-1 Interactions Using AFM 期刊论文
Polymer, 2006, 卷号: 47, 期号: 7, 页码: 2539-2547
作者:  Lv SQ(吕守芹);  Ye ZY(叶志义);  Zhu C(朱承);  Long M(龙勉);  Zhu, C (reprint author), Chinese Acad Sci, Inst Mech, Natl Micrograv Lab, Beijing 100080, Peoples R China.
Adobe PDF(456Kb)  |  收藏  |  浏览/下载:872/338  |  提交时间:2007/06/15
Quantifying the Effects of Molecular Orientation and Length on Two-Dimensional Receptor-Ligand Binding Kinetics 期刊论文
Journal of Biological Chemistry, 2004, 卷号: 279, 期号: 43, 页码: 44915-44923
作者:  Huang J;  Chen J;  Chesla SE;  Yago T;  Mehta P;  McEver RP;  Zhu C;  Long M(龙勉);  Zhu, C (reprint author), Georgia Inst Technol, George W Woodruff Sch Mech Engn, Atlanta, GA 30332 USA.
Adobe PDF(401Kb)  |  收藏  |  浏览/下载:1011/249  |  提交时间:2007/06/15