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The significance of molecular mechanics property to protein evolution 期刊论文
INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS, 2013, 卷号: 8, 期号: 1, 页码: 83-91
作者:  Zhang LM;  Liu X(刘鑫);  Liu, X (reprint author), Chinese Acad Sci, State Key Lab Nonlinear Mech, Inst Mech, 15 Beisihuanxi Rd, Beijing 100190, Peoples R China.
Adobe PDF(102Kb)  |  收藏  |  浏览/下载:476/180  |  提交时间:2013/09/09
Hydrophobic Interaction  Protein Evolution  Mechanics Property  
Outline and computational approaches of protein misfolding. 期刊论文
Frontiers of biology, 2010, 期号: 5, 页码: 211
作者:  Liu X(刘鑫)
Adobe PDF(1349Kb)  |  收藏  |  浏览/下载:691/193  |  提交时间:2010/05/12
Substitution Matrices of Residue Triplets Derived from Protein Blocks. 期刊论文
Journal of Computational Biology, 2010, 卷号: 17, 期号: 12, 页码: 1679
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥)
Adobe PDF(362Kb)  |  收藏  |  浏览/下载:818/214  |  提交时间:2010/12/21
hydrophobicity  Sequence Alignment  Twilight Zone.  
Switch Region for Pathogenic Structural Change in Conformational Disease and Its Prediction 期刊论文
PLoS One, 2010, 卷号: 5, 期号: 1, 页码: e8441
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥);  Zhao YP(赵亚溥)
浏览  |  Adobe PDF(670Kb)  |  收藏  |  浏览/下载:913/204  |  提交时间:2010/05/12
Generating artificial homologous proteins according to the representative family character in molecular mechanics properties - an attempt in validating an underlying rule of protein evolution 期刊论文
FEBS Letters, 2010, 卷号: 584, 期号: 5, 页码: 1059-1065
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥);  Zhao YP(赵亚溥)
浏览  |  Adobe PDF(895Kb)  |  收藏  |  浏览/下载:745/208  |  提交时间:2010/05/12
Donut-Shaped Fingerprint In Homologous Polypeptide Relationships-A Topological Feature Related To Pathogenic Structural Changes In Conformational Disease 期刊论文
Journal of Theoretical Biology, 2009, 卷号: 258, 期号: 2, 页码: 294-301
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥);  Zhao YP
Adobe PDF(513Kb)  |  收藏  |  浏览/下载:730/166  |  提交时间:2009/08/03
Homologous Relationship  Polypeptide  Prion Protein  Conformational Disease  Predicting Signal Peptides  State Enzyme-kinetics  Protein-structure  Graphic Rules  Codon Usage  Rate Laws  Evolution  Steady  Model  Prion  
A scheme for multiple sequences alignment optimization-an improvement based on family representative mechanics features 期刊论文
Journal of Theoretical Biology, 2009, 卷号: 261, 期号: 4, 页码: 593-597
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥)
Adobe PDF(493Kb)  |  收藏  |  浏览/下载:646/159  |  提交时间:2009/12/28
Scoring Scheme  Hydrophobic Interaction  Multiple Sequence Alignment  Homologous Proteins  
Significant Residue Features Revealed By Eigenvalue Decomposition Analysis Of Blosum Matrices 期刊论文
Physics Letters A, 2008, 页码: 2282-2285
作者:  Zhang LM;  Liu X(刘鑫);  Liu, X (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100080, Peoples R China.
Adobe PDF(242Kb)  |  收藏  |  浏览/下载:908/234  |  提交时间:2009/08/03
Protein Evolution  Residue Feature  Eigenvalue Decomposition  Blosum  Acid Substitution Matrices  Protein Blocks  
Clemaps: Multiple Alignment Of Protein Structures Based On Conformational Letters 期刊论文
Proteins-Structure Function And Bioinformatics, 2008, 页码: 728-736
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥);  Zheng WM(郑伟谋);  Zheng, WM (reprint author), Acad Sinica, Inst Theoret Phys, Beijing 100080, Peoples R China.
Adobe PDF(567Kb)  |  收藏  |  浏览/下载:595/153  |  提交时间:2009/08/03
Protein Structure  
A combined statistical model for multiple motifs search 期刊论文
Chinese Physics B, 2008, 卷号: 17, 期号: 12, 页码: 4396
作者:  Gao LF(高丽锋);  Liu X(刘鑫);  Guan S(官山);  Guan S
浏览  |  Adobe PDF(1074Kb)  |  收藏  |  浏览/下载:669/172  |  提交时间:2010/05/12
Transcription Factor Binding Sites  Motif  Position Weight Matrix