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Distinct binding kinetics of E-, P- and L-selectins to CD44 期刊论文
FEBS JOURNAL, 2022, 页码: 18
作者:  Li LD(李林达);  Ding QH(丁奇寒);  Zhou J(周瑾);  Wu Y(武亿);  Zhang MK(张明坤);  Guo XM;  Long M(龙勉);  Lv SQ(吕守芹)
Adobe PDF(5539Kb)  |  收藏  |  浏览/下载:261/74  |  提交时间:2022/01/12
binding epitope  binding kinetics  CD44  selectin  
E-selectin negatively regulates polymorphonuclear neutrophil transmigration through altered endothelial junction integrity 期刊论文
FASEB JOURNAL, 2021, 卷号: 35, 期号: 5, 页码: 15
作者:  Huang DD(黄丹丹);  Ding QH(丁奇寒);  Chen SB(陈深宝);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(2008Kb)  |  收藏  |  浏览/下载:255/75  |  提交时间:2021/08/03
cytoskeletal remodeling  endothelial integrity  E-selectin  neutrophil  transmigration  
Characterizing liver sinusoidal endothelial cell fenestrae on soft substrates upon AFM imaging and deep learning 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2020, 卷号: 1864, 期号: 12, 页码: 9
作者:  Li PW(李培文);  Zhou J(周瑾);  Li W(李旺);  Wu H(吴欢);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Lv SQ(吕守芹);  Pan J;  Zhang CY;  Li N(李宁);  Long M(龙勉)
Adobe PDF(4976Kb)  |  收藏  |  浏览/下载:647/375  |  提交时间:2020/11/30
Liver sinusoidal endothelial cells  Fenestrae  Atomic force microscopy  Imaging recognition  Fully convolutional networks  Substrate stiffness  
Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
作者:  Shu XY(舒芯钰);  Li N(李宁);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
浏览  |  Adobe PDF(1108Kb)  |  收藏  |  浏览/下载:434/162  |  提交时间:2020/04/07
beta(2) integrin  Ligands  Calcium transients  Bond strength  Mechanotransduction  Shear stress  
Flow-enhanced priming of hESCs through H2B acetylation and chromatin decondensation 期刊论文
STEM CELL RESEARCH & THERAPY, 2019, 卷号: 10, 期号: 1, 页码: 16
作者:  Wang JW(王家文);  Wu Y(武亿);  Zhang X(张潇);  Zhang F(张帆);  Lv DY(吕东媛);  Shang GB(上官冰);  Gao YX(高宇欣);  Long M(龙勉)
浏览  |  Adobe PDF(2406Kb)  |  收藏  |  浏览/下载:217/67  |  提交时间:2020/03/11
Embryonic stem cell  Fluid shear mechanomics  Nuclear spreading  Histone acetylation  Chromatin decondensation  
Microgravity-induced hepatogenic differentiation of rBMSCs on board the SJ-10 satellite 期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 3, 页码: 4273-4286
作者:  Lv DY(吕东媛);  Sun SJ(孙树津);  Zhang F(张帆);  Luo CH(罗春花);  Zheng L;  Wu Y(武毅);  Li N(李宁);  Zhang C;  Wang CZ;  Chen Q;  Long M(龙勉)
浏览  |  Adobe PDF(3477Kb)  |  收藏  |  浏览/下载:298/97  |  提交时间:2019/04/11
mesenchymal stem cells  mechanotransduction  hepatocyte  signaling pathway  
Life Science in Space: Experiments on Board the SJ-10 Recoverable Satellite 专著
Beijing;Singapore:Science Press; Springer, 2019
作者:  Editors: Duan EK;  Long M(龙勉)
Adobe PDF(21614Kb)  |  收藏  |  浏览/下载:261/0  |  提交时间:2019/12/18
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
作者:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
浏览  |  Adobe PDF(865Kb)  |  收藏  |  浏览/下载:387/188  |  提交时间:2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling 期刊论文
MOLECULAR BIOLOGY OF THE CELL, 2018, 卷号: 29, 期号: 4, 页码: 408-418
作者:  Li N(李宁);  Yang H(杨浩);  Wang ML;  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
浏览  |  Adobe PDF(1832Kb)  |  收藏  |  浏览/下载:401/94  |  提交时间:2018/10/30
Mechanical remodeling of normally sized mammalian cells under a gravity vector 期刊论文
FASEB JOURNAL, 2017, 卷号: 31, 期号: 2, 页码: 802-813
作者:  Zhang C;  Zhou LW(周吕文);  Zhang F(张帆);  Lv DY(吕东媛);  Li N(李宁);  Zheng L;  Xu YH(徐艳红);  Li Z;  Sun SJ(孙树津);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
浏览  |  Adobe PDF(3686Kb)  |  收藏  |  浏览/下载:484/153  |  提交时间:2017/07/24
Gravity-directed  Mechanosensing  Nucleus Translocation  Cytoskeletal Remodeling  Fac Reorganization