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Two Complementary Signaling Pathways Depict Eukaryotic Chemotaxis: A Mechanochemical Coupling Model 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9, 页码: 12
Authors:  Zhou LW(周吕文);  Feng SL(冯世亮);  Li L(李龙);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
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chemotaxis  cytoskeletal remodeling  mathematical model  biochemical  biomechanical  
Multi-scale molecular dynamics simulations and applications on mechanosensitive proteins of integrins* 期刊论文
CHINESE PHYSICS B, 2021, 卷号: 30, 期号: 3, 页码: 8
Authors:  Lv SQ(吕守芹);  Ding QH(丁奇寒);  Zhang MK(张明坤);  Long M(龙勉)
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molecular dynamics simulations  mechanosensitive protein  allosteric dynamics  integrin  
Characterizing liver sinusoidal endothelial cell fenestrae on soft substrates upon AFM imaging and deep learning 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2020, 卷号: 1864, 期号: 12, 页码: 9
Authors:  Li PW(李培文);  Zhou J(周瑾);  Li W(李旺);  Wu H(吴欢);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Lv SQ(吕守芹);  Pan J;  Zhang CY;  Li N(李宁);  Long M(龙勉)
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Liver sinusoidal endothelial cells  Fenestrae  Atomic force microscopy  Imaging recognition  Fully convolutional networks  Substrate stiffness  
Microtubule-Mediated Wall Anisotropy Contributes to Leaf Blade Flattening 期刊论文
CURRENT BIOLOGY, 2020, 卷号: 30, 期号: 20, 页码: 3972-+
Authors:  Zhao F;  Du F;  Oliveri H;  Zhou LW(周吕文);  Ali O;  Chen WQ;  Feng SL(冯世亮);  Wang QQ;  Lv SQ(吕守芹);  Long M(龙勉);  Schneider R;  Sampathkumar A;  Godin C;  Traas J;  Jiao YL
Adobe PDF(7322Kb)  |  Favorite  |  View/Download：257/69  |  Submit date：2020/11/30
Mechanochemical modeling of neutrophil migration based on four signaling layers, integrin dynamics, and substrate stiffness 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2018, 卷号: 17, 期号: 6, 页码: 1611-1630
Authors:  Feng SL(冯世亮);  Zhou LW(周吕文);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(3483Kb)  |  Favorite  |  View/Download：431/153  |  Submit date：2019/05/30
Chemotaxis  Cytoskeletal remodeling  Mathematical model  Biochemical  Biomechanical  
Binding of intercellular adhesion molecule 1 to beta(2)-integrin regulates distinct cell adhesion processes on hepatic and cerebral endothelium 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2018, 卷号: 315, 期号: 3, 页码: C409-C421
Authors:  Tong CF(佟春芳);  Zhang Y(章燕);  Lv SQ(吕守芹);  Li N(李宁);  Gong YX(龚一心);  Yang H;  Feng SL;  Du Y;  Huang DD;  Long M(龙勉)
View  |  Adobe PDF(1593Kb)  |  Favorite  |  View/Download：585/282  |  Submit date：2018/10/30
brain  ICAM-1  integrin  kinetics  liver  
Theoretical modeling of mechanical homeostasis of a mammalian cell under gravity-directed vector 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2018, 卷号: 17, 期号: 1, 页码: 191-203
Authors:  Zhou LW(周吕文);  Zhang C(张晨);  Zhang F(张芳);  Lv SQ(吕守芹);  Sun SJ(孙树津);  Lv DY(吕东媛);  Long M(龙勉)
View  |  Adobe PDF(860Kb)  |  Favorite  |  View/Download：429/230  |  Submit date：2018/10/30
Gravity directed  Mechanosensing  Nucleus translocation  Cytoskeletal remodeling  FAC reorganization  
Distinct binding affinities of Mac-1 and LFA-1 in neutrophil activation 期刊论文
JOURNAL OF IMMUNOLOGY, 2013, 卷号: 190, 期号: 8, 页码: 4371-4381
Authors:  Li N(李宁);  Mao DB(毛德斌);  Lv SQ(吕守芹);  Tong CF(佟春芳);  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Natl Micrograv Lab, Key Lab Micrograv, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
Adobe PDF(777Kb)  |  Favorite  |  View/Download：1435/367  |  Submit date：2013/05/21
Tyrosine replacement of PSGL-1 reduces association kinetics with P- and L-selectin on the cell membrane 期刊论文
BIOPHYSICAL JOURNAL, 2012, 卷号: 103, 期号: 4, 页码: 777-785
Authors:  Xiao BT(肖波涛);  Tong CF(佟春芳);  Jia XL(贾潇凌);  Guo R(郭瑞);  Lv SQ(吕守芹);  Zhang Y(章燕);  McEver RP;  Zhu C;  Long M(龙勉);  Long, MA;  Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100080, Peoples R China.
Adobe PDF(775Kb)  |  Favorite  |  View/Download：1047/283  |  Submit date：2013/01/18
Ligand Binding-kinetics  Glycoprotein Ligand-1  Molecular-dynamics  Adhesion  Sulfation  Proteins  Glycosulfopeptides  Identification  Dissociation  Recognition  
Low Spring Constant Regulates P-Selectin-Psgl-1 Bond Rupture 期刊论文
Biophysical Journal, 2008, 页码: 5439-5448
Authors:  Zhang Y(章燕);  Sun GY(孙淦云);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Natl Micrograv Lab, Beijing 100190, Peoples R China.
Adobe PDF(634Kb)  |  Favorite  |  View/Download：962/210  |  Submit date：2009/08/03
Selectin Glycoprotein Ligand-1  P-selectin  Cell-adhesion  Binding-kinetics  Force  Dissociation  Lifetime  Flow  Microscope  Leukocytes