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FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17
Authors:  Zhang XY(张晓宇);  Li PW(李培文);  Zhou J(周瑾);  Zhang ZL(张子良);  Wu H(吴欢);  Shu XY(舒芯钰);  Li W(李旺);  Wu Y(武亿);  Du Y(杜宇);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Favorite  |  View/Download：29/0  |  Submit date：2024/04/02
Liver sinusoidal endothelial cells  Fenestrae  Liver fibrosis  Cytoskeleton remodeling  FAK  MAPK  
Direct mechanical exposure initiates hepatocyte proliferation 期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
Authors:  Li, Wang;  Wu Y(武亿);  Hu, Wenhui;  Zhou J(周瑾);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang, Ziliang;  Wu, Huan;  Du, Yu;  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Adobe PDF(3334Kb)  |  Favorite  |  View/Download：70/4  |  Submit date：2024/01/02
Mechanotransduction  FAK  hepatic sinusoid chip  
真核细胞运动接触抑制行为的力学-化学耦合模拟 期刊论文
中国科学:物理学 力学 天文学, 2022, 卷号: 52, 期号: 12, 页码: 145-155
Authors:  陈亚君;  周吕文;  冯世亮;  吕守芹;  龙勉
Adobe PDF(2973Kb)  |  Favorite  |  View/Download：156/53  |  Submit date：2023/02/09
细胞骨架重组  力敏感信号通路  格子玻尔兹曼法  
Impact of real-time shedding on binding kinetics of membrane-remaining L-selectin to PSGL-1 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2019, 卷号: 316, 期号: 5, 页码: C678-C689
Authors:  Peng S(彭爽);  Chen SB(陈深宝);  Li LD(李林达);  Tong CF(佟春芳);  Li N(李宁);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(2200Kb)  |  Favorite  |  View/Download：416/212  |  Submit date：2019/12/02
binding kinetics  competitive binding  L-selectin  modeling  real-time shedding  
Microgravity-induced hepatogenic differentiation of rBMSCs on board the SJ-10 satellite 期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 3, 页码: 4273-4286
Authors:  Lv DY(吕东媛);  Sun SJ(孙树津);  Zhang F(张帆);  Luo CH(罗春花);  Zheng L;  Wu Y(武毅);  Li N(李宁);  Zhang C;  Wang CZ;  Chen Q;  Long M(龙勉)
Adobe PDF(3477Kb)  |  Favorite  |  View/Download：324/101  |  Submit date：2019/04/11
mesenchymal stem cells  mechanotransduction  hepatocyte  signaling pathway  
Mechanochemical modeling of neutrophil migration based on four signaling layers, integrin dynamics, and substrate stiffness 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2018, 卷号: 17, 期号: 6, 页码: 1611-1630
Authors:  Feng SL(冯世亮);  Zhou LW(周吕文);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(3483Kb)  |  Favorite  |  View/Download：431/153  |  Submit date：2019/05/30
Chemotaxis  Cytoskeletal remodeling  Mathematical model  Biochemical  Biomechanical  
Microgravity-Induced Alterations of Inflammation-Related Mechanotransduction in Endothelial Cells on Board SJ-10 Satellite 期刊论文
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9, 页码: 1025
Authors:  Li N(李宁);  Wang CZ(王成之);  Sun SJ(孙树津);  Zhang C(张晨);  Lv DY(吕东媛);  Chen Q(陈琴);  Long M(龙勉)
Adobe PDF(3456Kb)  |  Favorite  |  View/Download：627/427  |  Submit date：2018/10/19
Microgravity  Sj-10 Satellite  Endothelial Cells  Adhesive Molecules  Cytoskeleton  Mechanotransduction  Nitric Oxide  Exosome Rna  
肿瘤及其微环境的力学问题 期刊论文
力学进展, 2018, 卷号: 48, 期号: 1, 页码: 360-409
Authors:  施兴华;  张路姚;  李博;  冯西桥
Adobe PDF(8465Kb)  |  Favorite  |  View/Download：511/123  |  Submit date：2018/10/24
肿瘤微环境  生物力学  应力  药物输运  肿瘤转移  
Mechanomics: an emerging field between biology and biomechanics 期刊论文
Protein & Cell, 2014, 卷号: 5, 期号: 7, 页码: 518-531
Authors:  Wang JW;  Lv DY(吕东媛);  Mao DB(毛德斌);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Ctr Biomech & Bioengn, Beijing 100190, Peoples R China.
Adobe PDF(587Kb)  |  Favorite  |  View/Download：715/245  |  Submit date：2014/09/03
Mechanomics  Mechanobiology  Proteomics  Transcriptomics  
A Microfluidic-Based Multi-Shear Device for Investigating the Effects of Low Fluid-Induced Stresses on Osteoblasts 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 2, 页码: e89966
Authors:  Yu, WL;  Qu, H;  Hu GQ(胡国庆);  Zhang, Q;  Song, K;  Guan, HJ;  Liu, TJ;  Qin, JH;  Liu, TJ (reprint author), Dalian Med Univ, Coll Stomatol, Sect Oral Pathol, Dalian, Peoples R China.
Adobe PDF(4089Kb)  |  Favorite  |  View/Download：471/145  |  Submit date：2014/05/09
Elasto-plastic-damage Behavior  Anisotropy  Physical Mechanism  Finite Deformation  Constitutive Theory  Component Assembling Model