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FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17
Authors:  Zhang XY(张晓宇);  Li PW(李培文);  Zhou J(周瑾);  Zhang ZL(张子良);  Wu H(吴欢);  Shu XY(舒芯钰);  Li W(李旺);  Wu Y(武亿);  Du Y(杜宇);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Favorite  |  View/Download：26/0  |  Submit date：2024/04/02
Liver sinusoidal endothelial cells  Fenestrae  Liver fibrosis  Cytoskeleton remodeling  FAK  MAPK  
Direct mechanical exposure initiates hepatocyte proliferation 期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
Authors:  Li, Wang;  Wu Y(武亿);  Hu, Wenhui;  Zhou J(周瑾);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang, Ziliang;  Wu, Huan;  Du, Yu;  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Adobe PDF(3334Kb)  |  Favorite  |  View/Download：61/0  |  Submit date：2024/01/02
Mechanotransduction  FAK  hepatic sinusoid chip  
Binding of different hyaluronan to CD44 mediates distinct cell adhesion dynamics under shear flow 期刊论文
FEBS JOURNAL, 2023
Authors:  Li LD(李林达);  Ding QH(丁奇寒);  Wu Y(武亿);  Zheng Z(郑植);  Zhang XN(张晓宁);  Zhang MK(张明焜);  Long M(龙勉);  Lv SQ(吕守芹)
Adobe PDF(6108Kb)  |  Favorite  |  View/Download：64/1  |  Submit date：2023/07/17
CD44  HA  molecular weight  shear flow  two-dimensional interaction  
Trail Formation Alleviates Excessive Adhesion and Maintains Efficient Neutrophil Migration 期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2023
Authors:  Hu WH(胡文慧);  Gao WB(高文博);  Gong YX(龚一心);  Guo P(郭盼);  Li W(李旺);  Shu XY(舒芯钰);  Lv SQ(吕守芹);  Zeng, Zhu;  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(7494Kb)  |  Favorite  |  View/Download：78/3  |  Submit date：2023/04/20
neutrophil migration  trail release  rear contraction  fi2 integrin  cell adhesion  
Biphasic flow dynamics and polarized mass transportation in branched hepatic sinusoids 期刊论文
BIOMICROFLUIDICS, 2022, 卷号: 16, 期号: 5, 页码: 12
Authors:  Hao, Yinjing;  Lv SQ(吕守芹);  Li W(李旺);  Long M(龙勉);  Cui, Yuhong
Adobe PDF(3422Kb)  |  Favorite  |  View/Download：240/39  |  Submit date：2022/11/28
Two Complementary Signaling Pathways Depict Eukaryotic Chemotaxis: A Mechanochemical Coupling Model 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9, 页码: 12
Authors:  Zhou LW(周吕文);  Feng SL(冯世亮);  Li L(李龙);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(2763Kb)  |  Favorite  |  View/Download：238/46  |  Submit date：2022/01/13
chemotaxis  cytoskeletal remodeling  mathematical model  biochemical  biomechanical  
A Novel Human Antibody, HF, against HER2/erb-B2 Obtained by a Computer-Aided Antibody Design Method 期刊论文
ENGINEERING, 2021, 卷号: 7, 期号: 11, 页码: 1566-1576
Authors:  Qiao, Chunxia;  Lv, Ming;  Li, Xinying;  Lang, Xiaoling;  Lv SQ(吕守芹);  Long M(龙勉);  Li, Yan;  Geng, Shusheng;  Lin, Zhou;  Shen, Beifen;  Feng, Jiannan
Adobe PDF(4174Kb)  |  Favorite  |  View/Download：199/34  |  Submit date：2022/02/17
HER2/erb-B2  Human antibody  Computer-aided design  
Hepatic differentiation of human embryonic stem cells by coupling substrate stiffness and microtopography 期刊论文
BIOMATERIALS SCIENCE, 2021, 页码: 15
Authors:  Luo CH(罗春花);  Lv DY(吕东媛);  Zheng L(郑鲁);  Zhang F(张帆);  Zhang X(张潇);  Lv SQ(吕守芹);  Zhang C(张晨);  Jia Xiaohua;  Shu XY(舒芯钰);  Li PW(李培文);  Li Z(李展);  Long M(龙勉)
Adobe PDF(7505Kb)  |  Favorite  |  View/Download：315/163  |  Submit date：2021/05/17
Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Wu Y(武亿);  Li W(李旺);  Zhang XY(张晓宇);  Li PW(李培文);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1359Kb)  |  Favorite  |  View/Download：394/110  |  Submit date：2021/05/06
Liver sinusoidal endothelial cell  Shear stress  Mechanical stretch  Extracellular matrix  Stiffness  
Matrix stiffness and shear stresses modulate hepatocyte functions in a fibrotic liver sinusoidal model 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2020, 卷号: 320, 期号: 3, 页码: G272-G282
Authors:  Li W(李旺);  Li PW(李培文);  Li N(李宁);  Du Y(杜宇);  Lv SQ(吕守芹);  Elad, David;  Long M(龙勉)
Adobe PDF(2812Kb)  |  Favorite  |  View/Download：202/101  |  Submit date：2022/10/25
hepatocytes  liver fibrosis  matrix stiffness  shear flow  three-dimensional liver sinusoidal model