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Distinct binding kinetics of E-, P- and L-selectins to CD44 期刊论文
FEBS JOURNAL, 2022, 页码: 18
Authors:  Li LD(李林达);  Ding QH(丁奇寒);  Zhou J(周瑾);  Wu Y(武亿);  Zhang MK(张明坤);  Guo XM;  Long M(龙勉);  Lv SQ(吕守芹)
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binding epitope  binding kinetics  CD44  selectin  
Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Wu Y(武亿);  Li W(李旺);  Zhang XY(张晓宇);  Li PW(李培文);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Long M(龙勉)
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Liver sinusoidal endothelial cell  Shear stress  Mechanical stretch  Extracellular matrix  Stiffness  
Multi-scale molecular dynamics simulations and applications on mechanosensitive proteins of integrins* 期刊论文
CHINESE PHYSICS B, 2021, 卷号: 30, 期号: 3, 页码: 8
Authors:  Lv SQ(吕守芹);  Ding QH(丁奇寒);  Zhang MK(张明坤);  Long M(龙勉)
Adobe PDF(834Kb)  |  Favorite  |  View/Download:296/91  |  Submit date:2021/04/19
molecular dynamics simulations  mechanosensitive protein  allosteric dynamics  integrin  
CD44-配体相互作用的生物力学与功能调控 期刊论文
力学学报, 2021, 卷号: 53, 期号: 02, 页码: 539-553
Authors:  李林达;  丁奇寒;  陈深宝;  吕守芹;  龙勉;  郭兴明
Adobe PDF(796Kb)  |  Favorite  |  View/Download:435/103  |  Submit date:2021/04/19
CD44  选择素  透明质酸  细胞粘附  力学调控  炎症反应  
Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(1108Kb)  |  Favorite  |  View/Download:495/186  |  Submit date:2020/04/07
beta(2) integrin  Ligands  Calcium transients  Bond strength  Mechanotransduction  Shear stress  
Biomechanical stress regulates mammalian tooth replacement via the integrin beta 1-RUNX2-Wnt pathway 期刊论文
EMBO JOURNAL, 2020, 卷号: 39, 期号: 3, 页码: 19
Authors:  Wu XS;  Hu JR(胡锦荣);  Li GQ;  Li Y;  Li Y;  Zhang J;  Wang F;  Li A;  Hu L;  Fan ZP;  Lv SQ(吕守芹);  Ding G;  Zhang CM;  Wang JS;  Long M(龙勉);  Wang SL
Adobe PDF(7490Kb)  |  Favorite  |  View/Download:274/72  |  Submit date:2020/03/11
biomechanics  organ replacement  stress  Wnt signaling  
Mechanical Point Loading Induces Cortex Stiffening and Actin Reorganization 期刊论文
BIOPHYSICAL JOURNAL, 2019, 卷号: 117, 期号: 8, 页码: 1405-1418
Authors:  Hu JR(胡锦荣);  Chen SB(陈深宝);  Hu WH(胡文慧);  Lv SQ(吕守芹);  Long M(龙勉)
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Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
Authors:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
View  |  Adobe PDF(865Kb)  |  Favorite  |  View/Download:423/200  |  Submit date:2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling 期刊论文
MOLECULAR BIOLOGY OF THE CELL, 2018, 卷号: 29, 期号: 4, 页码: 408-418
Authors:  Li N(李宁);  Yang H(杨浩);  Wang ML;  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
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Mechanokinetics of receptor-ligand interactions in cell adhesion 期刊论文
Acta Mechanica Sinica, 2015, 卷号: 31, 期号: 2, 页码: 248-258
Authors:  Li N(李宁);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Ctr Biomech & Bioengn, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100190, Peoples R China.
View  |  Adobe PDF(809Kb)  |  Favorite  |  View/Download:560/170  |  Submit date:2015/07/21
Receptor-ligand Interactions  Selectins  Beta(2) Integrins  2d Binding Kinetics