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Gravity-Vector Induces Mechanical Remodeling of rMSCs via Combined Substrate Stiffness and Orientation 期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022, 卷号: 9, 页码: 14
Authors:  Zhang C(张晨);  Lv DY(吕东媛);  Zhang F(张帆);  Wu Y(武亿);  Zheng L(郑鲁);  Zhang XY(张晓宇);  Li Z(李展);  Sun SJ(孙树津);  龙勉Mian
Adobe PDF(3580Kb)  |  Favorite  |  View/Download：159/51  |  Submit date：2022/05/17
substrate stiffness  orientation  mechanosensing  nucleus translocation  cytoskeletal remodeling  focal adhesion complex reorganization  cellular morphology  
Hepatic differentiation of human embryonic stem cells by coupling substrate stiffness and microtopography 期刊论文
BIOMATERIALS SCIENCE, 2021, 页码: 15
Authors:  Luo CH(罗春花);  Lv DY(吕东媛);  Zheng L(郑鲁);  Zhang F(张帆);  Zhang X(张潇);  Lv SQ(吕守芹);  Zhang C(张晨);  Jia Xiaohua;  Shu XY(舒芯钰);  Li PW(李培文);  Li Z(李展);  Long M(龙勉)
Adobe PDF(7505Kb)  |  Favorite  |  View/Download：311/160  |  Submit date：2021/05/17
Regulation of hepatic differentiation of human embryonic stem cells by calcium silicate extracts for liver injury repairing 期刊论文
Applied Materials Today, 2020, 卷号: 20, 页码: 100730
Authors:  Zheng L;  Lv DY(吕东媛);  Zhang F;  Xing M;  Wang XY;  Jia XH;  Shu XY;  Li PW(李培文);  Lv SQ(吕守芹);  Chang J;  Long M(龙勉)
Adobe PDF(3951Kb)  |  Favorite  |  View/Download：197/73  |  Submit date：2021/01/29
Human embryonic stem cells  Hepatic differentiation  Hepatocyte-like cells  Calcium silicate extracts  Liver injury repair  
Mechanomics analysis of hESCs under combined mechanical shear, stretch, and compression 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2020, 页码: 18
Authors:  Zhang F(张帆);  Wang JW(王家文);  Lv DY(吕东媛);  Zheng L(郑璐);  Shang GB(上官冰);  Gao YX(高宇欣);  Wu Y(武亿);  Long M(龙勉)
Adobe PDF(8050Kb)  |  Favorite  |  View/Download：317/170  |  Submit date：2020/10/23
Mechanomics  hESCs  iTRAQ  GSEA  WGCNA  
Microgravity-induced hepatogenic differentiation of rBMSCs on board the SJ-10 satellite 期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 3, 页码: 4273-4286
Authors:  Lv DY(吕东媛);  Sun SJ(孙树津);  Zhang F(张帆);  Luo CH(罗春花);  Zheng L;  Wu Y(武毅);  Li N(李宁);  Zhang C;  Wang CZ;  Chen Q;  Long M(龙勉)
View  |  Adobe PDF(3477Kb)  |  Favorite  |  View/Download：309/99  |  Submit date：2019/04/11
mesenchymal stem cells  mechanotransduction  hepatocyte  signaling pathway  
Computational model of wound healing: EGF secreted by fibroblasts promotes delayed re-epithelialization of epithelial keratinocytes 期刊论文
INTEGRATIVE BIOLOGY, 2018, 卷号: 10, 期号: 10, 页码: 605-634
Authors:  Andasari V;  Lv DY(吕东媛);  Swat M;  Feng SL(冯世亮);  Spill F;  Chen L;  Luo XD;  Zaman M;  Long M(龙勉)
View  |  Adobe PDF(12579Kb)  |  Favorite  |  View/Download：268/101  |  Submit date：2019/05/30
Mechanical remodeling of normally sized mammalian cells under a gravity vector 期刊论文
FASEB JOURNAL, 2017, 卷号: 31, 期号: 2, 页码: 802-813
Authors:  Zhang C;  Zhou LW(周吕文);  Zhang F(张帆);  Lv DY(吕东媛);  Li N(李宁);  Zheng L;  Xu YH(徐艳红);  Li Z;  Sun SJ(孙树津);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
View  |  Adobe PDF(3686Kb)  |  Favorite  |  View/Download：496/158  |  Submit date：2017/07/24
Gravity-directed  Mechanosensing  Nucleus Translocation  Cytoskeletal Remodeling  Fac Reorganization  
Bioactive calcium silicate extracts regulate the morphology and stemness of human embryonic stem cells at the initial stage 期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 106, 页码: 104666-104674
Authors:  Zhang F;  Lv DY(吕东媛);  Li HY;  Luo CH;  Chang J;  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Ctr Biomech & Bioengn, Beijing 100190, Peoples R China.;  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Natl Micrograv Lab, Key Lab Micrograv, Beijing 100190, Peoples R China.;  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, Beijing 100190, Peoples R China.;  Chang, J (reprint author), Chinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China.
View  |  Adobe PDF(1218Kb)  |  Favorite  |  View/Download：441/111  |  Submit date：2017/02/24
Differential regulation of stiffness, topography, and dimension of substrates in rat mesenchymal stem cells 期刊论文
BIOMATERIALS, 2013, 卷号: 34, 期号: 31, 页码: 7616-7625
Authors:  Li Z(李展);  Gong YW(宫元卫);  Sun SJ(孙树津);  Du Y(杜宇);  Lv DY(吕东媛);  Liu XF(刘晓锋);  Long M(龙勉);  Sun, SJ (reprint author), Chinese Acad Sci, Ctr Biomech & Bioengn, Beijing 100190, Peoples R China.
Adobe PDF(1994Kb)  |  Favorite  |  View/Download：1932/756  |  Submit date：2013/09/27
Stiffness  Topography  Dimension  Stem Cell  Proliferation  Differentiation