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FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17
作者:  Zhang XY(张晓宇);  Li PW(李培文);  Zhou J(周瑾);  Zhang ZL(张子良);  Wu H(吴欢);  Shu XY(舒芯钰);  Li W(李旺);  Wu Y(武亿);  Du Y(杜宇);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
收藏  |  浏览/下载:21/0  |  提交时间:2024/04/02
Liver sinusoidal endothelial cells  Fenestrae  Liver fibrosis  Cytoskeleton remodeling  FAK  MAPK  
Direct mechanical exposure initiates hepatocyte proliferation 期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
作者:  Li, Wang;  Wu Y(武亿);  Hu, Wenhui;  Zhou J(周瑾);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang, Ziliang;  Wu, Huan;  Du, Yu;  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Adobe PDF(3334Kb)  |  收藏  |  浏览/下载:57/0  |  提交时间:2024/01/02
Mechanotransduction  FAK  hepatic sinusoid chip  
Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
作者:  Shu XY(舒芯钰);  Li N(李宁);  Wu Y(武亿);  Li W(李旺);  Zhang XY(张晓宇);  Li PW(李培文);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1359Kb)  |  收藏  |  浏览/下载:386/108  |  提交时间:2021/05/06
Liver sinusoidal endothelial cell  Shear stress  Mechanical stretch  Extracellular matrix  Stiffness  
Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
作者:  Shu XY(舒芯钰);  Li N(李宁);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1108Kb)  |  收藏  |  浏览/下载:466/172  |  提交时间:2020/04/07
beta(2) integrin  Ligands  Calcium transients  Bond strength  Mechanotransduction  Shear stress  
Cells' Flow and Immune Cell Priming under alternating g-forces in Parabolic Flight 期刊论文
SCIENTIFIC REPORTS, 2019, 卷号: 9, 页码: 11
作者:  Moser D;  Sun SJ(孙树津);  Li N(李宁);  Biere K;  Hoerl M;  Matzel S;  Feuerecker M;  Buchheim JI;  Strewe C;  Thiel CS;  Gao YX(高宇欣);  Wang CZ(王成之);  Ullrich O;  Long M(龙勉);  Chouker A
Adobe PDF(2234Kb)  |  收藏  |  浏览/下载:200/38  |  提交时间:2019/09/10
Impact of real-time shedding on binding kinetics of membrane-remaining L-selectin to PSGL-1 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2019, 卷号: 316, 期号: 5, 页码: C678-C689
作者:  Peng S(彭爽);  Chen SB(陈深宝);  Li LD(李林达);  Tong CF(佟春芳);  Li N(李宁);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(2200Kb)  |  收藏  |  浏览/下载:396/203  |  提交时间:2019/12/02
binding kinetics  competitive binding  L-selectin  modeling  real-time shedding  
Microgravity-induced hepatogenic differentiation of rBMSCs on board the SJ-10 satellite 期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 3, 页码: 4273-4286
作者:  Lv DY(吕东媛);  Sun SJ(孙树津);  Zhang F(张帆);  Luo CH(罗春花);  Zheng L;  Wu Y(武毅);  Li N(李宁);  Zhang C;  Wang CZ;  Chen Q;  Long M(龙勉)
Adobe PDF(3477Kb)  |  收藏  |  浏览/下载:307/98  |  提交时间:2019/04/11
mesenchymal stem cells  mechanotransduction  hepatocyte  signaling pathway  
An integration design of gas exchange, bubble separation, and flow control in a space cell culture system on board the SJ-10 satellite 期刊论文
REVIEW OF SCIENTIFIC INSTRUMENTS, 2019, 卷号: 90, 期号: 7, 页码: 12
作者:  Sun SJ(孙树津);  Wang CZ(王成之);  Bi YZ(毕于振);  Li N(李宁);  Lv DY(吕东媛);  Chen Q(陈琴);  Chen J(陈娟);  Long M(龙勉)
浏览  |  Adobe PDF(9094Kb)  |  收藏  |  浏览/下载:334/183  |  提交时间:2019/09/09
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
作者:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
浏览  |  Adobe PDF(865Kb)  |  收藏  |  浏览/下载:403/193  |  提交时间:2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Microgravity-Induced Alterations of Inflammation-Related Mechanotransduction in Endothelial Cells on Board SJ-10 Satellite 期刊论文
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9, 页码: 1025
作者:  Li N(李宁);  Wang CZ(王成之);  Sun SJ(孙树津);  Zhang C(张晨);  Lv DY(吕东媛);  Chen Q(陈琴);  Long M(龙勉)
浏览  |  Adobe PDF(3456Kb)  |  收藏  |  浏览/下载:610/417  |  提交时间:2018/10/19
Microgravity  Sj-10 Satellite  Endothelial Cells  Adhesive Molecules  Cytoskeleton  Mechanotransduction  Nitric Oxide  Exosome Rna