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Two Complementary Signaling Pathways Depict Eukaryotic Chemotaxis: A Mechanochemical Coupling Model 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9, 页码: 12
Authors:  Zhou LW(周吕文);  Feng SL(冯世亮);  Li L(李龙);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
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chemotaxis  cytoskeletal remodeling  mathematical model  biochemical  biomechanical  
A Novel Human Antibody, HF, against HER2/erb-B2 Obtained by a Computer-Aided Antibody Design Method 期刊论文
ENGINEERING, 2021, 卷号: 7, 期号: 11, 页码: 1566-1576
Authors:  Qiao, Chunxia;  Lv, Ming;  Li, Xinying;  Lang, Xiaoling;  Lv SQ(吕守芹);  Long M(龙勉);  Li, Yan;  Geng, Shusheng;  Lin, Zhou;  Shen, Beifen;  Feng, Jiannan
Adobe PDF(4174Kb)  |  Favorite  |  View/Download：194/31  |  Submit date：2022/02/17
HER2/erb-B2  Human antibody  Computer-aided design  
Mapping the morphological identifiers of distinct conformations via the protein translocation current in nanopores 期刊论文
NANOSCALE, 2021, 卷号: 13, 期号: 12, 页码: 14
Authors:  Zhang MK(张明坤);  Chen SB(陈深宝);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Li LD(李林达);  Lv SQ(吕守芹);  Long M(龙勉)
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Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Wu Y(武亿);  Li W(李旺);  Zhang XY(张晓宇);  Li PW(李培文);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1359Kb)  |  Favorite  |  View/Download：387/108  |  Submit date：2021/05/06
Liver sinusoidal endothelial cell  Shear stress  Mechanical stretch  Extracellular matrix  Stiffness  
Multi-scale molecular dynamics simulations and applications on mechanosensitive proteins of integrins* 期刊论文
CHINESE PHYSICS B, 2021, 卷号: 30, 期号: 3, 页码: 8
Authors:  Lv SQ(吕守芹);  Ding QH(丁奇寒);  Zhang MK(张明坤);  Long M(龙勉)
Adobe PDF(834Kb)  |  Favorite  |  View/Download：278/88  |  Submit date：2021/04/19
molecular dynamics simulations  mechanosensitive protein  allosteric dynamics  integrin  
Mechanically Regulated Outside-In Activation of an I-Domain-Containing Integrin 期刊论文
BIOPHYSICAL JOURNAL, 2020, 卷号: 119, 期号: 5, 页码: 966-977
Authors:  Mao DB(毛德斌);  Lv SQ(吕守芹);  Zhang X(张潇);  Long M(龙勉)
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Mechanical Point Loading Induces Cortex Stiffening and Actin Reorganization 期刊论文
BIOPHYSICAL JOURNAL, 2019, 卷号: 117, 期号: 8, 页码: 1405-1418
Authors:  Hu JR(胡锦荣);  Chen SB(陈深宝);  Hu WH(胡文慧);  Lv SQ(吕守芹);  Long M(龙勉)
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Mechanochemical modeling of neutrophil migration based on four signaling layers, integrin dynamics, and substrate stiffness 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2018, 卷号: 17, 期号: 6, 页码: 1611-1630
Authors:  Feng SL(冯世亮);  Zhou LW(周吕文);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(3483Kb)  |  Favorite  |  View/Download：413/143  |  Submit date：2019/05/30
Chemotaxis  Cytoskeletal remodeling  Mathematical model  Biochemical  Biomechanical  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
Authors:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
View  |  Adobe PDF(865Kb)  |  Favorite  |  View/Download：409/194  |  Submit date：2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Flow dynamics analyses of pathophysiological liver lobules using porous media theory 期刊论文
ACTA MECHANICA SINICA, 2017, 卷号: 33, 期号: 4, 页码: 823-832
Authors:  Hu JR(胡锦荣);  Lv SQ(吕守芹);  Feng, Shiliang;  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Key Lab Micrograv, Natl Micrograv Lab, Ctr Biomech & Bioengn,Inst Mech,Beijing Key Lab E, Beijing 100190, Peoples R China.;  Long, M (reprint author), Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China.
View  |  Adobe PDF(1617Kb)  |  Favorite  |  View/Download：386/117  |  Submit date：2017/10/27
Cirrhotic Liver  Structural Distortion  Portal Hypertension  Collateral Vessels