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FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17
Authors:  Zhang XY(张晓宇);  Li PW(李培文);  Zhou J(周瑾);  Zhang ZL(张子良);  Wu H(吴欢);  Shu XY(舒芯钰);  Li W(李旺);  Wu Y(武亿);  Du Y(杜宇);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Favorite  |  View/Download:27/0  |  Submit date:2024/04/02
Liver sinusoidal endothelial cells  Fenestrae  Liver fibrosis  Cytoskeleton remodeling  FAK  MAPK  
Numerical simulation of flow characteristics in a permeable liver sinusoid with leukocytes 期刊论文
BIOPHYSICAL JOURNAL, 2022, 卷号: 121, 期号: 23, 页码: 4666-4678
Authors:  Chen SB(陈深宝);  Zhu, Jingchen;  Xue J(薛健);  Wang, Xiaolong;  Jing, Peng;  Zhou, Luwen;  Cui, Yuhong;  Wang, Tianhao;  Gong, Xiaobo;  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(3140Kb)  |  Favorite  |  View/Download:227/71  |  Submit date:2023/02/07
Biphasic flow dynamics and polarized mass transportation in branched hepatic sinusoids 期刊论文
BIOMICROFLUIDICS, 2022, 卷号: 16, 期号: 5, 页码: 12
Authors:  Hao, Yinjing;  Lv SQ(吕守芹);  Li W(李旺);  Long M(龙勉);  Cui, Yuhong
Adobe PDF(3422Kb)  |  Favorite  |  View/Download:256/42  |  Submit date:2022/11/28
Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer 期刊论文
ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448
Authors:  Li N(李宁);  Zhang XY(张晓宇);  Zhou J(周瑾);  Li W(李旺);  Shu XY(舒芯钰);  Wu Y(武亿);  Long M(龙勉)
Adobe PDF(2553Kb)  |  Favorite  |  View/Download:356/104  |  Submit date:2022/10/23
Liver tissue stiffness  Shear stress  Hydrostatic pressure  Hepatocytes  Hepatocellular carcinoma  Liver sinusoidal endothelial cells  Hepatic stellate cells  Mechanotransduction pathways  Mechanomedicine  Drug design and delivery  
Influence of microflow on hepatic sinusoid blood flow and red blood cell deformation 期刊论文
BIOPHYSICAL JOURNAL, 2021, 卷号: 120, 期号: 21, 页码: 4859-4873
Authors:  Wang, Tianhao;  Lv SQ(吕守芹);  Hao, Yinjing;  Su, Zinan;  Long M(龙勉);  Cui, Yuhong
Adobe PDF(3057Kb)  |  Favorite  |  View/Download:219/46  |  Submit date:2022/01/12
Hepatic differentiation of human embryonic stem cells by coupling substrate stiffness and microtopography 期刊论文
BIOMATERIALS SCIENCE, 2021, 页码: 15
Authors:  Luo CH(罗春花);  Lv DY(吕东媛);  Zheng L(郑鲁);  Zhang F(张帆);  Zhang X(张潇);  Lv SQ(吕守芹);  Zhang C(张晨);  Jia Xiaohua;  Shu XY(舒芯钰);  Li PW(李培文);  Li Z(李展);  Long M(龙勉)
Adobe PDF(7505Kb)  |  Favorite  |  View/Download:321/166  |  Submit date:2021/05/17
Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Wu Y(武亿);  Li W(李旺);  Zhang XY(张晓宇);  Li PW(李培文);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1359Kb)  |  Favorite  |  View/Download:401/113  |  Submit date:2021/05/06
Liver sinusoidal endothelial cell  Shear stress  Mechanical stretch  Extracellular matrix  Stiffness  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
Authors:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
Adobe PDF(865Kb)  |  Favorite  |  View/Download:418/197  |  Submit date:2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Functional collagen conduits combined with human mesenchymal stem cells promote regeneration after sciatic nerve transection in dogs 期刊论文
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2018, 卷号: 12, 期号: 5, 页码: 1285-1296
Authors:  Cui Y;  Yao Y;  Zhao YN;  Xiao ZF;  Cao ZF;  Han SF;  Li X;  Huan Y(郇勇);  Pan JL;  Dai JW
View  |  Adobe PDF(1819Kb)  |  Favorite  |  View/Download:371/159  |  Submit date:2018/07/17
Dog  Human Umbilical Cord Mesenchymal Stem Cells (Huc-mscs)  Longitudinally Oriented Collagen Conduit (Locc)  Nerve Regeneration  Sciatic Nerve  
Flow dynamics analyses of pathophysiological liver lobules using porous media theory 期刊论文
ACTA MECHANICA SINICA, 2017, 卷号: 33, 期号: 4, 页码: 823-832
Authors:  Hu JR(胡锦荣);  Lv SQ(吕守芹);  Feng, Shiliang;  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Key Lab Micrograv, Natl Micrograv Lab, Ctr Biomech & Bioengn,Inst Mech,Beijing Key Lab E, Beijing 100190, Peoples R China.;  Long, M (reprint author), Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China.
View  |  Adobe PDF(1617Kb)  |  Favorite  |  View/Download:398/121  |  Submit date:2017/10/27
Cirrhotic Liver  Structural Distortion  Portal Hypertension  Collateral Vessels