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| FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文 BIOMATERIALS, 2024, 卷号: 305, 页码: 17 Authors: Zhang XY(张晓宇); Li PW(李培文); Zhou J(周瑾); Zhang ZL(张子良); Wu H(吴欢); Shu XY(舒芯钰); Li W(李旺); Wu Y(武亿); Du Y(杜宇); Lv DY(吕东媛); Lv SQ(吕守芹); Li N(李宁); Long M(龙勉) Favorite  |  View/Download:26/0  |  Submit date:2024/04/02 Liver sinusoidal endothelial cells Fenestrae Liver fibrosis Cytoskeleton remodeling FAK MAPK |
| Direct mechanical exposure initiates hepatocyte proliferation 期刊论文 JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13 Authors: Li, Wang; Wu Y(武亿); Hu, Wenhui; Zhou J(周瑾); Shu XY(舒芯钰); Zhang XY(张晓宇); Zhang, Ziliang; Wu, Huan; Du, Yu; Lv DY(吕东媛); Lv SQ(吕守芹); Li N(李宁); Long M(龙勉) Adobe PDF(3334Kb)  |  Favorite  |  View/Download:64/2  |  Submit date:2024/01/02 Mechanotransduction FAK hepatic sinusoid chip |
| Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文 ACTA MECHANICA SINICA, 2021, 页码: 17 Authors: Shu XY(舒芯钰); Li N(李宁); Wu Y(武亿); Li W(李旺); Zhang XY(张晓宇); Li PW(李培文); Lv DY(吕东媛); Lv SQ(吕守芹); Long M(龙勉) Adobe PDF(1359Kb)  |  Favorite  |  View/Download:397/111  |  Submit date:2021/05/06 Liver sinusoidal endothelial cell Shear stress Mechanical stretch Extracellular matrix Stiffness |
| Characterizing liver sinusoidal endothelial cell fenestrae on soft substrates upon AFM imaging and deep learning 期刊论文 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2020, 卷号: 1864, 期号: 12, 页码: 9 Authors: Li PW(李培文); Zhou J(周瑾); Li W(李旺); Wu H(吴欢); Hu JR(胡锦荣); Ding QH(丁奇寒); Lv SQ(吕守芹); Pan J; Zhang CY; Li N(李宁); Long M(龙勉) Adobe PDF(4976Kb)  |  Favorite  |  View/Download:687/387  |  Submit date:2020/11/30 Liver sinusoidal endothelial cells Fenestrae Atomic force microscopy Imaging recognition Fully convolutional networks Substrate stiffness |
| Matrix stiffness and shear stresses modulate hepatocyte functions in a fibrotic liver sinusoidal model 期刊论文 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2020, 卷号: 320, 期号: 3, 页码: G272-G282 Authors: Li W(李旺); Li PW(李培文); Li N(李宁); Du Y(杜宇); Lv SQ(吕守芹); Elad, David; Long M(龙勉) Adobe PDF(2812Kb)  |  Favorite  |  View/Download:205/102  |  Submit date:2022/10/25 hepatocytes liver fibrosis matrix stiffness shear flow three-dimensional liver sinusoidal model |
| Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文 EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7 Authors: Shu XY(舒芯钰); Li N(李宁); Huang DD(黄丹丹); Zhang Y(章燕); Lv SQ(吕守芹); Long M(龙勉) View  |  Adobe PDF(1108Kb)  |  Favorite  |  View/Download:483/180  |  Submit date:2020/04/07 beta(2) integrin Ligands Calcium transients Bond strength Mechanotransduction Shear stress |
| Cell Growth and Differentiation Under Microgravity 图书章节 2019 Authors: Sun SJ(孙树津); Wang CZ(王成之); Li N(李宁); Lv DY(吕东媛); Chen Q(陈琴); Long M(龙勉) View  |  Adobe PDF(1205Kb)  |  Favorite  |  View/Download:198/44  |  Submit date:2019/12/26 |
| Cells' Flow and Immune Cell Priming under alternating g-forces in Parabolic Flight 期刊论文 SCIENTIFIC REPORTS, 2019, 卷号: 9, 页码: 11 Authors: Moser D; Sun SJ(孙树津); Li N(李宁); Biere K; Hoerl M; Matzel S; Feuerecker M; Buchheim JI; Strewe C; Thiel CS; Gao YX(高宇欣); Wang CZ(王成之); Ullrich O; Long M(龙勉); Chouker A View  |  Adobe PDF(2234Kb)  |  Favorite  |  View/Download:207/41  |  Submit date:2019/09/10 |
| Impact of real-time shedding on binding kinetics of membrane-remaining L-selectin to PSGL-1 期刊论文 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2019, 卷号: 316, 期号: 5, 页码: C678-C689 Authors: Peng S(彭爽); Chen SB(陈深宝); Li LD(李林达); Tong CF(佟春芳); Li N(李宁); Lv SQ(吕守芹); Long M(龙勉) View  |  Adobe PDF(2200Kb)  |  Favorite  |  View/Download:408/208  |  Submit date:2019/12/02 binding kinetics competitive binding L-selectin modeling real-time shedding |
| Microgravity-induced hepatogenic differentiation of rBMSCs on board the SJ-10 satellite 期刊论文 FASEB JOURNAL, 2019, 卷号: 33, 期号: 3, 页码: 4273-4286 Authors: Lv DY(吕东媛); Sun SJ(孙树津); Zhang F(张帆); Luo CH(罗春花); Zheng L; Wu Y(武毅); Li N(李宁); Zhang C; Wang CZ; Chen Q; Long M(龙勉) View  |  Adobe PDF(3477Kb)  |  Favorite  |  View/Download:320/100  |  Submit date:2019/04/11 mesenchymal stem cells mechanotransduction hepatocyte signaling pathway |