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Biphasic flow dynamics and polarized mass transportation in branched hepatic sinusoids 期刊论文
BIOMICROFLUIDICS, 2022, 卷号: 16, 期号: 5, 页码: 12
Authors:  Hao, Yinjing;  Lv SQ(吕守芹);  Li W(李旺);  Long M(龙勉);  Cui, Yuhong
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Influence of microflow on hepatic sinusoid blood flow and red blood cell deformation 期刊论文
BIOPHYSICAL JOURNAL, 2021, 卷号: 120, 期号: 21, 页码: 4859-4873
Authors:  Wang, Tianhao;  Lv SQ(吕守芹);  Hao, Yinjing;  Su, Zinan;  Long M(龙勉);  Cui, Yuhong
Adobe PDF(3057Kb)  |  Favorite  |  View/Download:225/49  |  Submit date:2022/01/12
Flow field analyses of a porous membrane-separated, double-layered microfluidic chip for cell co-culture 期刊论文
ACTA MECHANICA SINICA, 2020, 页码: 14
Authors:  Chen SB(陈深宝);  Xue J(薛健);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Zhou LW(周吕文);  Feng SL(冯世亮);  Cui YH;  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(5919Kb)  |  Favorite  |  View/Download:298/141  |  Submit date:2020/08/26
Immersed boundary method  Porous membrane  Wall shear stress  Penetration velocity  Microfluidic chip  
Binding of intercellular adhesion molecule 1 to beta(2)-integrin regulates distinct cell adhesion processes on hepatic and cerebral endothelium 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2018, 卷号: 315, 期号: 3, 页码: C409-C421
Authors:  Tong CF(佟春芳);  Zhang Y(章燕);  Lv SQ(吕守芹);  Li N(李宁);  Gong YX(龚一心);  Yang H;  Feng SL;  Du Y;  Huang DD;  Long M(龙勉)
View  |  Adobe PDF(1593Kb)  |  Favorite  |  View/Download:585/282  |  Submit date:2018/10/30
brain  ICAM-1  integrin  kinetics  liver  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
Authors:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
View  |  Adobe PDF(865Kb)  |  Favorite  |  View/Download:424/200  |  Submit date:2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Mimicking liver sinusoidal structures and functions using a 3D-configured microfluidic chip 期刊论文
LAB ON A CHIP, 2017, 卷号: 17, 期号: 5, 页码: 782-794
Authors:  Du Y(杜宇);  Li N(李宁);  Yang H(杨浩);  Luo CH(罗春花);  Gong YX;  Tong CF(佟春芳);  Gao YX(高宇新);  Lv SQ(吕守芹);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Key Lab Micrograv, Natl Micrograv Lab, Ctr Biomech & Bioengn, Beijing 100190, Peoples R China.;  Long, M (reprint author), Chinese Acad Sci, Beijing Key Lab Engn Construct & Mech, Inst Mech, Beijing 100190, Peoples R China.;  Long, M (reprint author), Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China.
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Combined modeling of cell aggregation and adhesion mediated by receptor-ligand interactions under shear flow 期刊论文
Theoretical and Applied Mechanics Letters, 2015, 卷号: 5, 期号: 6, 页码: 216-221
Authors:  Du Y(杜宇);  Peng S(彭爽);  Cui Yuhong;  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
View  |  Adobe PDF(961Kb)  |  Favorite  |  View/Download:408/64  |  Submit date:2017/09/26
Cell Adhesion  Aggregation  Kinetics  Shear Flow  
Molecular dynamics simulation of shear- and stretch-induced dissociation of P-selectin/PSGL-1 complex 期刊论文
BIOPHYSICAL JOURNAL, 2012, 卷号: 102, 期号: 1, 页码: 112-120
Authors:  Kang YY(康英永);  Lv SQ(吕守芹);  Ren P(任鹏);  Huo B(霍波);  Long M(龙勉);  Huo, B (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100080, Peoples R China.
Adobe PDF(1143Kb)  |  Favorite  |  View/Download:985/201  |  Submit date:2013/01/18
Selectin Glycoprotein Ligand-1  Granule Membrane-protein  P-selectin  Cell-adhesion  Beta-switch  Endothelial-cells  Catch Bonds  Ib-alpha  Flow  Transition  
Probe stiffness regulates receptor-ligand bond lifetime under force 期刊论文
Science China-Physics Mechanics & Astronomy, 2011, 卷号: 54, 期号: 5, 页码: 923-929
Authors:  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100190, Peoples R China
Adobe PDF(534Kb)  |  Favorite  |  View/Download:1377/265  |  Submit date:2012/04/01
Probe Stiffness  Bond Lifetime  Optical Trap  Selectin Glycoprotein Ligand-1  P-selectin  Cell-adhesion  Binding-kinetics  Leukocytes  Molecule  Psgl-1  Flow  
Low Spring Constant Regulates P-Selectin-Psgl-1 Bond Rupture 期刊论文
Biophysical Journal, 2008, 页码: 5439-5448
Authors:  Zhang Y(章燕);  Sun GY(孙淦云);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Natl Micrograv Lab, Beijing 100190, Peoples R China.
Adobe PDF(634Kb)  |  Favorite  |  View/Download:961/210  |  Submit date:2009/08/03
Selectin Glycoprotein Ligand-1  P-selectin  Cell-adhesion  Binding-kinetics  Force  Dissociation  Lifetime  Flow  Microscope  Leukocytes