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Characterizing liver sinusoidal endothelial cell fenestrae on soft substrates upon AFM imaging and deep learning 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2020, 卷号: 1864, 期号: 12, 页码: 9
Authors:  Li PW(李培文);  Zhou J(周瑾);  Li W(李旺);  Wu H(吴欢);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Lv SQ(吕守芹);  Pan J;  Zhang CY;  Li N(李宁);  Long M(龙勉)
Adobe PDF(4976Kb)  |  Favorite  |  View/Download：683/386  |  Submit date：2020/11/30
Liver sinusoidal endothelial cells  Fenestrae  Atomic force microscopy  Imaging recognition  Fully convolutional networks  Substrate stiffness  
Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(1108Kb)  |  Favorite  |  View/Download：479/178  |  Submit date：2020/04/07
beta(2) integrin  Ligands  Calcium transients  Bond strength  Mechanotransduction  Shear stress  
Cells' Flow and Immune Cell Priming under alternating g-forces in Parabolic Flight 期刊论文
SCIENTIFIC REPORTS, 2019, 卷号: 9, 页码: 11
Authors:  Moser D;  Sun SJ(孙树津);  Li N(李宁);  Biere K;  Hoerl M;  Matzel S;  Feuerecker M;  Buchheim JI;  Strewe C;  Thiel CS;  Gao YX(高宇欣);  Wang CZ(王成之);  Ullrich O;  Long M(龙勉);  Chouker A
View  |  Adobe PDF(2234Kb)  |  Favorite  |  View/Download：205/40  |  Submit date：2019/09/10
Impact of real-time shedding on binding kinetics of membrane-remaining L-selectin to PSGL-1 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2019, 卷号: 316, 期号: 5, 页码: C678-C689
Authors:  Peng S(彭爽);  Chen SB(陈深宝);  Li LD(李林达);  Tong CF(佟春芳);  Li N(李宁);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(2200Kb)  |  Favorite  |  View/Download：405/207  |  Submit date：2019/12/02
binding kinetics  competitive binding  L-selectin  modeling  real-time shedding  
An integration design of gas exchange, bubble separation, and flow control in a space cell culture system on board the SJ-10 satellite 期刊论文
REVIEW OF SCIENTIFIC INSTRUMENTS, 2019, 卷号: 90, 期号: 7, 页码: 12
Authors:  Sun SJ(孙树津);  Wang CZ(王成之);  Bi YZ(毕于振);  Li N(李宁);  Lv DY(吕东媛);  Chen Q(陈琴);  Chen J(陈娟);  Long M(龙勉)
View  |  Adobe PDF(9094Kb)  |  Favorite  |  View/Download：339/184  |  Submit date：2019/09/09
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
Authors:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
View  |  Adobe PDF(865Kb)  |  Favorite  |  View/Download：413/195  |  Submit date：2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Microgravity-Induced Alterations of Inflammation-Related Mechanotransduction in Endothelial Cells on Board SJ-10 Satellite 期刊论文
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9, 页码: 1025
Authors:  Li N(李宁);  Wang CZ(王成之);  Sun SJ(孙树津);  Zhang C(张晨);  Lv DY(吕东媛);  Chen Q(陈琴);  Long M(龙勉)
View  |  Adobe PDF(3456Kb)  |  Favorite  |  View/Download：622/423  |  Submit date：2018/10/19
Microgravity  Sj-10 Satellite  Endothelial Cells  Adhesive Molecules  Cytoskeleton  Mechanotransduction  Nitric Oxide  Exosome Rna  
Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling 期刊论文
MOLECULAR BIOLOGY OF THE CELL, 2018, 卷号: 29, 期号: 4, 页码: 408-418
Authors:  Li N(李宁);  Yang H(杨浩);  Wang ML;  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
View  |  Adobe PDF(1832Kb)  |  Favorite  |  View/Download：433/104  |  Submit date：2018/10/30
Liver sinusoid on a chip 期刊论文
MICROFLUIDICS IN CELL BIOLOGY, PT A: MICROFLUIDICS FOR MULTICELLULAR SYSTEMS, 2018, 卷号: 146, 页码: 105-134
Authors:  Du Y(杜宇);  Li N(李宁);  Long M(龙勉)
View  |  Adobe PDF(3794Kb)  |  Favorite  |  View/Download：565/280  |  Submit date：2019/05/30
Neutrophil adhesion and crawling dynamics on liver sinusoidal endothelial cells under shear flow 期刊论文
EXPERIMENTAL CELL RESEARCH, 2017, 卷号: 351, 期号: 1, 页码: 91-99
Authors:  Yang H(杨浩);  Li N(李宁);  Du Y(杜宇);  Tong CF(佟春芳);  Lv SQ(吕守芹);  Hu JR;  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100190, Peoples R China.
View  |  Adobe PDF(2025Kb)  |  Favorite  |  View/Download：717/281  |  Submit date：2017/07/24
Neutrophils  Liver Sinusoids  Shear Flow  Adhesive Molecules  Kupffer Cells