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Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Wu Y(武亿);  Li W(李旺);  Zhang XY(张晓宇);  Li PW(李培文);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1359Kb)  |  Favorite  |  View/Download：425/118  |  Submit date：2021/05/06
Liver sinusoidal endothelial cell  Shear stress  Mechanical stretch  Extracellular matrix  Stiffness  
Characterizing liver sinusoidal endothelial cell fenestrae on soft substrates upon AFM imaging and deep learning 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2020, 卷号: 1864, 期号: 12, 页码: 9
Authors:  Li PW(李培文);  Zhou J(周瑾);  Li W(李旺);  Wu H(吴欢);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Lv SQ(吕守芹);  Pan J;  Zhang CY;  Li N(李宁);  Long M(龙勉)
Adobe PDF(4976Kb)  |  Favorite  |  View/Download：719/395  |  Submit date：2020/11/30
Liver sinusoidal endothelial cells  Fenestrae  Atomic force microscopy  Imaging recognition  Fully convolutional networks  Substrate stiffness  
Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(1108Kb)  |  Favorite  |  View/Download：508/191  |  Submit date：2020/04/07
beta(2) integrin  Ligands  Calcium transients  Bond strength  Mechanotransduction  Shear stress  
Cells' Flow and Immune Cell Priming under alternating g-forces in Parabolic Flight 期刊论文
SCIENTIFIC REPORTS, 2019, 卷号: 9, 页码: 11
Authors:  Moser D;  Sun SJ(孙树津);  Li N(李宁);  Biere K;  Hoerl M;  Matzel S;  Feuerecker M;  Buchheim JI;  Strewe C;  Thiel CS;  Gao YX(高宇欣);  Wang CZ(王成之);  Ullrich O;  Long M(龙勉);  Chouker A
View  |  Adobe PDF(2234Kb)  |  Favorite  |  View/Download：222/50  |  Submit date：2019/09/10
Impact of real-time shedding on binding kinetics of membrane-remaining L-selectin to PSGL-1 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2019, 卷号: 316, 期号: 5, 页码: C678-C689
Authors:  Peng S(彭爽);  Chen SB(陈深宝);  Li LD(李林达);  Tong CF(佟春芳);  Li N(李宁);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(2200Kb)  |  Favorite  |  View/Download：431/216  |  Submit date：2019/12/02
binding kinetics  competitive binding  L-selectin  modeling  real-time shedding  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
Authors:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
View  |  Adobe PDF(865Kb)  |  Favorite  |  View/Download：433/203  |  Submit date：2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling 期刊论文
MOLECULAR BIOLOGY OF THE CELL, 2018, 卷号: 29, 期号: 4, 页码: 408-418
Authors:  Li N(李宁);  Yang H(杨浩);  Wang ML;  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
View  |  Adobe PDF(1832Kb)  |  Favorite  |  View/Download：474/110  |  Submit date：2018/10/30
Liver sinusoid on a chip 期刊论文
MICROFLUIDICS IN CELL BIOLOGY, PT A: MICROFLUIDICS FOR MULTICELLULAR SYSTEMS, 2018, 卷号: 146, 页码: 105-134
Authors:  Du Y(杜宇);  Li N(李宁);  Long M(龙勉)
View  |  Adobe PDF(3794Kb)  |  Favorite  |  View/Download：590/285  |  Submit date：2019/05/30
Neutrophil adhesion and crawling dynamics on liver sinusoidal endothelial cells under shear flow 期刊论文
EXPERIMENTAL CELL RESEARCH, 2017, 卷号: 351, 期号: 1, 页码: 91-99
Authors:  Yang H(杨浩);  Li N(李宁);  Du Y(杜宇);  Tong CF(佟春芳);  Lv SQ(吕守芹);  Hu JR;  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100190, Peoples R China.
View  |  Adobe PDF(2025Kb)  |  Favorite  |  View/Download：756/294  |  Submit date：2017/07/24
Neutrophils  Liver Sinusoids  Shear Flow  Adhesive Molecules  Kupffer Cells  
Mechanical remodeling of normally sized mammalian cells under a gravity vector 期刊论文
FASEB JOURNAL, 2017, 卷号: 31, 期号: 2, 页码: 802-813
Authors:  Zhang C;  Zhou LW(周吕文);  Zhang F(张帆);  Lv DY(吕东媛);  Li N(李宁);  Zheng L;  Xu YH(徐艳红);  Li Z;  Sun SJ(孙树津);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
View  |  Adobe PDF(3686Kb)  |  Favorite  |  View/Download：521/163  |  Submit date：2017/07/24
Gravity-directed  Mechanosensing  Nucleus Translocation  Cytoskeletal Remodeling  Fac Reorganization