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Two Complementary Signaling Pathways Depict Eukaryotic Chemotaxis: A Mechanochemical Coupling Model 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9, 页码: 12
Authors:  Zhou LW(周吕文);  Feng SL(冯世亮);  Li L(李龙);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
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chemotaxis  cytoskeletal remodeling  mathematical model  biochemical  biomechanical  
E-selectin negatively regulates polymorphonuclear neutrophil transmigration through altered endothelial junction integrity 期刊论文
FASEB JOURNAL, 2021, 卷号: 35, 期号: 5, 页码: 15
Authors:  Huang DD(黄丹丹);  Ding QH(丁奇寒);  Chen SB(陈深宝);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(2008Kb)  |  Favorite  |  View/Download:286/91  |  Submit date:2021/08/03
cytoskeletal remodeling  endothelial integrity  E-selectin  neutrophil  transmigration  
Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(1108Kb)  |  Favorite  |  View/Download:503/190  |  Submit date:2020/04/07
beta(2) integrin  Ligands  Calcium transients  Bond strength  Mechanotransduction  Shear stress  
E-选择素调控白细胞跨内皮转运中内皮细胞骨架重组动力学 期刊论文
医用生物力学, 2019, 卷号: 34, 期号: S1, 页码: 143-144
Authors:  黄丹丹;  龚一心;  章燕;  龙勉
View  |  Adobe PDF(143Kb)  |  Favorite  |  View/Download:363/51  |  Submit date:2019/09/12
E-选择素  Arp2/3  细胞骨架重组  低阻抗区  白细胞迁移  
Mechanochemical modeling of neutrophil migration based on four signaling layers, integrin dynamics, and substrate stiffness 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2018, 卷号: 17, 期号: 6, 页码: 1611-1630
Authors:  Feng SL(冯世亮);  Zhou LW(周吕文);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(3483Kb)  |  Favorite  |  View/Download:437/155  |  Submit date:2019/05/30
Chemotaxis  Cytoskeletal remodeling  Mathematical model  Biochemical  Biomechanical  
Binding of intercellular adhesion molecule 1 to beta(2)-integrin regulates distinct cell adhesion processes on hepatic and cerebral endothelium 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2018, 卷号: 315, 期号: 3, 页码: C409-C421
Authors:  Tong CF(佟春芳);  Zhang Y(章燕);  Lv SQ(吕守芹);  Li N(李宁);  Gong YX(龚一心);  Yang H;  Feng SL;  Du Y;  Huang DD;  Long M(龙勉)
View  |  Adobe PDF(1593Kb)  |  Favorite  |  View/Download:588/283  |  Submit date:2018/10/30
brain  ICAM-1  integrin  kinetics  liver  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
Authors:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
View  |  Adobe PDF(865Kb)  |  Favorite  |  View/Download:429/202  |  Submit date:2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling 期刊论文
MOLECULAR BIOLOGY OF THE CELL, 2018, 卷号: 29, 期号: 4, 页码: 408-418
Authors:  Li N(李宁);  Yang H(杨浩);  Wang ML;  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
View  |  Adobe PDF(1832Kb)  |  Favorite  |  View/Download:466/107  |  Submit date:2018/10/30
Neutrophil adhesion and crawling dynamics on liver sinusoidal endothelial cells under shear flow 期刊论文
EXPERIMENTAL CELL RESEARCH, 2017, 卷号: 351, 期号: 1, 页码: 91-99
Authors:  Yang H(杨浩);  Li N(李宁);  Du Y(杜宇);  Tong CF(佟春芳);  Lv SQ(吕守芹);  Hu JR;  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100190, Peoples R China.
View  |  Adobe PDF(2025Kb)  |  Favorite  |  View/Download:751/292  |  Submit date:2017/07/24
Neutrophils  Liver Sinusoids  Shear Flow  Adhesive Molecules  Kupffer Cells  
Analyses of movement and contact of two nucleated cells using a gas-driven micropipette aspiration technique 期刊论文
JOURNAL OF IMMUNOLOGICAL METHODS, 2016, 卷号: 428, 页码: 20-29
Authors:  Yang H;  Tong CF;  Fu CL;  Xu YH;  Liu XF;  Chen Q;  Zhang Y(章燕);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100190, Peoples R China.
View  |  Adobe PDF(1237Kb)  |  Favorite  |  View/Download:939/563  |  Submit date:2016/03/21
Nucleated Cells  Movement  Contact  Adhesion  Pipette