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Multi-scale molecular dynamics simulations and applications on mechanosensitive proteins of integrins* 期刊论文
CHINESE PHYSICS B, 2021, 卷号: 30, 期号: 3, 页码: 8
Authors:  Lv SQ(吕守芹);  Ding QH(丁奇寒);  Zhang MK(张明坤);  Long M(龙勉)
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molecular dynamics simulations  mechanosensitive protein  allosteric dynamics  integrin  
Mechanochemical modeling of neutrophil migration based on four signaling layers, integrin dynamics, and substrate stiffness 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2018, 卷号: 17, 期号: 6, 页码: 1611-1630
Authors:  Feng SL(冯世亮);  Zhou LW(周吕文);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(3483Kb)  |  Favorite  |  View/Download：416/145  |  Submit date：2019/05/30
Chemotaxis  Cytoskeletal remodeling  Mathematical model  Biochemical  Biomechanical  
Binding of intercellular adhesion molecule 1 to beta(2)-integrin regulates distinct cell adhesion processes on hepatic and cerebral endothelium 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2018, 卷号: 315, 期号: 3, 页码: C409-C421
Authors:  Tong CF(佟春芳);  Zhang Y(章燕);  Lv SQ(吕守芹);  Li N(李宁);  Gong YX(龚一心);  Yang H;  Feng SL;  Du Y;  Huang DD;  Long M(龙勉)
View  |  Adobe PDF(1593Kb)  |  Favorite  |  View/Download：569/275  |  Submit date：2018/10/30
brain  ICAM-1  integrin  kinetics  liver  
Mechanokinetics of receptor-ligand interactions in cell adhesion 期刊论文
Acta Mechanica Sinica, 2015, 卷号: 31, 期号: 2, 页码: 248-258
Authors:  Li N(李宁);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Ctr Biomech & Bioengn, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100190, Peoples R China.
View  |  Adobe PDF(809Kb)  |  Favorite  |  View/Download：546/166  |  Submit date：2015/07/21
Receptor-ligand Interactions  Selectins  Beta(2) Integrins  2d Binding Kinetics  
Combined modeling of cell aggregation and adhesion mediated by receptor-ligand interactions under shear flow 期刊论文
Theoretical and Applied Mechanics Letters, 2015, 卷号: 5, 期号: 6, 页码: 216-221
Authors:  Du Y(杜宇);  Peng S(彭爽);  Cui Yuhong;  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
View  |  Adobe PDF(961Kb)  |  Favorite  |  View/Download：378/59  |  Submit date：2017/09/26
Cell Adhesion  Aggregation  Kinetics  Shear Flow  
Mechanomics: an emerging field between biology and biomechanics 期刊论文
Protein & Cell, 2014, 卷号: 5, 期号: 7, 页码: 518-531
Authors:  Wang JW;  Lv DY(吕东媛);  Mao DB(毛德斌);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Ctr Biomech & Bioengn, Beijing 100190, Peoples R China.
View  |  Adobe PDF(587Kb)  |  Favorite  |  View/Download：698/242  |  Submit date：2014/09/03
Mechanomics  Mechanobiology  Proteomics  Transcriptomics  
Spring constant regulate selectin-ligand bond dissociation 会议论文
第五届中美生物医学工程暨海内外生物力学学术研讨会, 中国北京/Beijing, China, 2013-08-01
Authors:  Zhang Y(章燕);  Sun GY(孙淦云);  Lv SQ(吕守芹);  Long M(龙勉)
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Dissociation  Regulate  Selectin  Constant  Formation  Further  Increased  Stiffness  Lifetime  Ligand  Binding  Assay  Probe  Force  Kinetics  Mainly  Reverse  Values  Well  Found  
Tyrosine replacement of PSGL-1 reduces association kinetics with P- and L-selectin on the cell membrane 期刊论文
BIOPHYSICAL JOURNAL, 2012, 卷号: 103, 期号: 4, 页码: 777-785
Authors:  Xiao BT(肖波涛);  Tong CF(佟春芳);  Jia XL(贾潇凌);  Guo R(郭瑞);  Lv SQ(吕守芹);  Zhang Y(章燕);  McEver RP;  Zhu C;  Long M(龙勉);  Long, MA;  Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100080, Peoples R China.
Adobe PDF(775Kb)  |  Favorite  |  View/Download：1036/273  |  Submit date：2013/01/18
Ligand Binding-kinetics  Glycoprotein Ligand-1  Molecular-dynamics  Adhesion  Sulfation  Proteins  Glycosulfopeptides  Identification  Dissociation  Recognition  
分子动力学模拟与分子生物力学 期刊论文
生物物理学报, 2012, 卷号: 28, 期号: 1, 页码: 6-14
Authors:  吕守芹;  龙勉
Adobe PDF(378Kb)  |  Favorite  |  View/Download：2735/573  |  Submit date：2013/01/16
分子动力学模拟  分子生物力学  微观结构动力学  结构-功能关系  
Advances in Experiments and Modeling in Micro- and Nano-Biomechanics: A Mini Review 期刊论文
Cellular and Molecular Bioengineering, 2011, 卷号: 4, 期号: 3, 页码: 327-339
Authors:  Long M(龙勉);  Sato M;  Lim CT;  Wu JH;  Adachi T;  Inoue Y;  Long, M (reprint author), Chinese Acad Sci, Key Lab Micrograv, Ctr Biomech & Bioengn, Inst Mech, Beijing 100190, Peoples R China
Adobe PDF(2481Kb)  |  Favorite  |  View/Download：1622/341  |  Submit date：2012/04/01
Cellular Mechanics  Molecular Biomechanics  Experimental Techniques  Theoretical Modeling  Computations  Fluid Shear-stress  Endothelial-cell Proliferation  Adhesive Dynamics Simulation  Ligand Binding-kinetics  Glycoprotein-ib-alpha  Von-willebrand-factor  Molecular-dynamics  Mechanical-stress  Beta-switch  2-dimensional Kinetics